7-DEAZA-2'-DEOXYGUANOSINE
- Product Name
- 7-DEAZA-2'-DEOXYGUANOSINE
- CAS No.
- 86392-75-8
- Chemical Name
- 7-DEAZA-2'-DEOXYGUANOSINE
- Synonyms
- 7-Deaza-2'-dG;7-deaza-2´7-DEAZE-2'-Deoxyguanosine;7-DEAZA-2'-DEOXYGUANOSINE;7-Deaza-2'-deoxy-D-guanosine;7-DEAZA-2'-DEOXYGUANOSINE USP/EP/BP;7-Deaza-2′-deoxyguanosine, CAS 86392-75-8;1,4-dichloro-2-methyl-5-propan-2-ylbenzene;2-Amino-7-(2-deoxy--D-ribofuranosyl)-7H-pyrrolo[2,3-d]pyrimidin-4(3H)-one;2-Amino-7-(2-deoxy-b-D-ribofuranosyl)-7H-pyrrolo[2,3-d]pyrimidin-4(3H)-one
- CBNumber
- CB3110038
- Molecular Formula
- C11H14N4O4
- Formula Weight
- 266.25
- MOL File
- 86392-75-8.mol
7-DEAZA-2'-DEOXYGUANOSINE Property
- Melting point:
- 262-265 °C
- Density
- 1.90±0.1 g/cm3(Predicted)
- storage temp.
- Keep in dark place,Sealed in dry,Store in freezer, under -20°C
- pka
- 11.29±0.20(Predicted)
- Appearance
- White to off-white Solid
- Crystal Structure
- Orthorhombic, colorless needles
- Space group
- P2₁2₁2₁
- Lattice constant
- a = 5.4146(12) Å, b = 10.969(2) Å, c = 19.968(4) Å, V = 1185.9(4) ų, Z = 4
- InChI
- InChI=1/C11H14N4O4/c12-11-13-9-5(10(18)14-11)1-2-15(9)8-3-6(17)7(4-16)19-8/h1-2,6-8,16-17H,3-4H2,(H3,12,13,14,18)/t6-,7+,8+/s3
- InChIKey
- PFCLMNDDPTZJHQ-JUCUSOLINA-N
- SMILES
- N1(C=CC2C(=O)NC(N)=NC1=2)[C@H]1C[C@H](O)[C@@H](CO)O1 |&1:11,13,15,r|
N-Bromosuccinimide Price
- Product number
- ND02887
- Product name
- 7-Deaza-2'-deoxyguanosine
- Packaging
- 25mg
- Price
- $60
- Updated
- 2021/12/16
- Product number
- ND02887
- Product name
- 7-Deaza-2'-deoxyguanosine
- Packaging
- 50mg
- Price
- $110
- Updated
- 2021/12/16
- Product number
- X7279
- Product name
- 7-Deaza-2'-deoxyguanosine
- Packaging
- 25mg
- Price
- $131
- Updated
- 2021/12/16
- Product number
- ND02887
- Product name
- 7-Deaza-2'-deoxyguanosine
- Packaging
- 100mg
- Price
- $190
- Updated
- 2021/12/16
- Product number
- ND02887
- Product name
- 7-Deaza-2'-deoxyguanosine
- Packaging
- 250mg
- Price
- $400
- Updated
- 2021/12/16
7-DEAZA-2'-DEOXYGUANOSINE Chemical Properties,Usage,Production
Description
7-Deaza-2'-deoxyguanosine is one of the most widely used modified nucleosides in the fields of chemistry, molecular biology and nanotechnology. It is known for its applications in the form of its 5'-triphosphate in Sanger DNA sequencing. As 7-deaza-2'-deoxyguanosine cannot form dG-tetramers, band compression in gel electrophoresis is reduced. Furthermore, replacing 2′-deoxyguanosine with 7-deaza-2′-deoxyguanosine enhances the sensitivity of MALDI-TOF (matrix-assisted laser desorption time-of-flight) mass spectrometry analysis of DNA fragments[1].
Definition
ChEBI: 7-Deaza-2'-deoxyguanosine is a pyrrolopyrimidine.
Synthesis
7-DEAZA-2'-DEOXYGUANOSINE was synthesized from 7‑(2‑deoxy‑β‑D‑erythro‑pentofuranosyl)‑4‑methoxy‑7H‑pyrrolo[2,3‑d]pyrimidin‑2‑amine according to the method of Winkeler & Seela (1983)[1].
References
[1] Frank Seela, Henning E., Khalil I. Shaikh. (2005). 7-Deaza-2’-deoxyguanosine. Acta Crystallographica. Section C, Crystal Structure Communications, 61 Pt 3, o151-3. https://doi.org/10.1107/S0108270105000971
7-DEAZA-2'-DEOXYGUANOSINE Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 7-DEAZA-2'-DEOXYGUANOSINE manufacturers
- Product
- 7-Deaza-2'-deoxyguanosine 86392-75-8
- Price
- US $0.00-0.00/g
- Min. Order
- 10g
- Purity
- 97%
- Supply Ability
- 100kg
- Release date
- 2025-07-28
- Product
- 7-DEAZA-2'-DEOXYGUANOSINE 86392-75-8
- Price
- US $0.00-0.00/G
- Min. Order
- 1G
- Purity
- 98%
- Supply Ability
- 2000
- Release date
- 2025-05-30
- Product
- 7-DEAZA-2'-DEOXYGUANOSINE 86392-75-8
- Price
- US $0.00-0.00/kg
- Min. Order
- 1kg
- Purity
- 98%
- Supply Ability
- 1Ton
- Release date
- 2022-09-23