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TERT-BUTYL TRIMETHYLSILYLACETATE

Product Name
TERT-BUTYL TRIMETHYLSILYLACETATE
CAS No.
41108-81-0
Chemical Name
TERT-BUTYL TRIMETHYLSILYLACETATE
Synonyms
Einecs 255-222-2;t-Butyl Trimethylsilylacetate;TERT-BUTYL TRIMETHYLSILYLACETATE;tert-butyl 2-trimethylsilylacetate;1,1-dimethylethyl trimethylsilylacetate;(Trimethylsilyl)acetic acid 1,1-dimethylethyl ester;Acetic acid, 2-(trimethylsilyl)-, 1,1-dimethylethyl ester
CBNumber
CB3110801
Molecular Formula
C9H20O2Si
Formula Weight
188.34
MOL File
41108-81-0.mol
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TERT-BUTYL TRIMETHYLSILYLACETATE Property

Boiling point:
67 °C13 mm Hg(lit.)
Density 
0.86 g/mL at 25 °C(lit.)
refractive index 
n20/D 1.417
Flash point:
42 °C
solubility 
Chloroform (Soluble), Methanol (Soluble)
form 
Oil
color 
Colourless
BRN 
1930256
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Safety

Risk Statements 
10
Safety Statements 
23-24/25
RIDADR 
UN 3272 3/PG 3
WGK Germany 
3
10-21
HazardClass 
3.2
PackingGroup 
III
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H226Flammable liquid and vapour

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
92759
Product name
tert-Butyl trimethylsilylacetate
Purity
≥95.0% (GC)
Packaging
5ml
Price
$66.2
Updated
2022/05/15
TRC
Product number
B693870
Product name
tert-Butyl trimethylsilylacetate
Packaging
25g
Price
$825
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
ORS0000928
Product name
TERT-BUTYL TRIMETHYLSILYLACETATE
Purity
95.00%
Packaging
5G
Price
$826.98
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
ORS0000928
Product name
TERT-BUTYL TRIMETHYLSILYLACETATE
Purity
95.00%
Packaging
5ML
Price
$975.4
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
ORS0000928
Product name
TERT-BUTYL TRIMETHYLSILYLACETATE
Purity
95.00%
Packaging
10G
Price
$1150.38
Updated
2021/12/16
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TERT-BUTYL TRIMETHYLSILYLACETATE Chemical Properties,Usage,Production

Physical properties

air stable, colorless liquid; bp 67°C/13 mmHg; n20 D 1.4184; 1H NMR (CDCl3, 90 MHz) 0.13 (s, 9H), 1.45 (s, 9H), 1.80 (s, 2H); IR 1710 cm?1.

Uses

t-Butyl Trimethylsilylacetate is used to prepare lithium enolates which can be alkylated;can be alkenated with aldehydes and ketones;can be acylated;can be reacted with Group 14 halides.
Most applications require initial formation of the enolate (1) (eq 1), which is obtained as a white solid suspended in THF, stable indefinitely at ?78°C.

Preparation

an advantage of t-butyl trimethylsilylacetate over its methyl and ethyl ester analogs is that it can be prepared by C-silylation of the lithium enolate of t-butyl acetate at ?78°C in THF (85–90% yield). Under the same conditions the enolates of methyl and ethyl acetate give primarily O-silylated products.The reagent has also been prepared by a rapid boron trifluoride etherate catalyzed reaction of trimethylsilylketene with t-butyl alcohol.

TERT-BUTYL TRIMETHYLSILYLACETATE Preparation Products And Raw materials

Raw materials

Preparation Products

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TERT-BUTYL TRIMETHYLSILYLACETATE Suppliers

CARBONE SCIENTIFIC CO.,LTD
Tel
--
Fax
--
Email
sales@carbonesci.com
Country
United Kingdom
ProdList
6666
Advantage
30

41108-81-0, TERT-BUTYL TRIMETHYLSILYLACETATERelated Search:


  • TERT-BUTYL TRIMETHYLSILYLACETATE
  • 1,1-dimethylethyl trimethylsilylacetate
  • t-Butyl Trimethylsilylacetate
  • (Trimethylsilyl)acetic acid 1,1-dimethylethyl ester
  • Einecs 255-222-2
  • tert-butyl 2-trimethylsilylacetate
  • Acetic acid, 2-(trimethylsilyl)-, 1,1-dimethylethyl ester
  • 41108-81-0
  • Building Blocks
  • C8 to C9
  • Carbonyl Compounds
  • Organic Building Blocks
  • Esters
  • C8 to C9
  • Carbonyl Compounds
  • Esters