2-Amino-pyrimidine-5-boronic acid
- Product Name
- 2-Amino-pyrimidine-5-boronic acid
- CAS No.
- 936250-22-5
- Chemical Name
- 2-Amino-pyrimidine-5-boronic acid
- Synonyms
- >=95.0%;Minimum purity 95.0%;2-Amino-5-boronopyrimidine;2-AMinopyriMidine-5-boronic;2-Aminopyrimidine-5-boron...;2-Aminopyrimidine-5-boronicaci;2-aMino-4-pyMidine boronic acid;2-AMino-5-pyriMidineboronic acid;2-Aminopyrimidine-5-boronic acid;2-Aminopyrimidine-5-ylboronic acid
- CBNumber
- CB31113135
- Molecular Formula
- C4H6BN3O2
- Formula Weight
- 138.92
- MOL File
- 936250-22-5.mol
2-Amino-pyrimidine-5-boronic acid Property
- Melting point:
- 206-211 °C
- Boiling point:
- 487.0±55.0 °C(Predicted)
- Density
- 1.44±0.1 g/cm3(Predicted)
- storage temp.
- 2-8°C
- solubility
- DMSO (Slightly, Heated), Methanol (Slightly, Heated)
- form
- Solid
- pka
- 2.58±0.11(Predicted)
- color
- Off-White
- Stability:
- Hygroscopic
- InChI
- 1S/C4H6BN3O2/c6-4-7-1-3(2-8-4)5(9)10/h1-2,9-10H,(H2,6,7,8)
- InChIKey
- CGHYQZASLKERLV-UHFFFAOYSA-N
- SMILES
- Nc1ncc(cn1)B(O)O
Safety
- Hazard Codes
- Xi
- Risk Statements
- 36/37/38
- Safety Statements
- 26-36/37/39
- WGK Germany
- 2
- HS Code
- 2933599590
- Storage Class
- 11 - Combustible Solids
- Hazard Classifications
- Eye Irrit. 2
Skin Irrit. 2
STOT SE 3
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P271Use only outdoors or in a well-ventilated area.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- 706221
- Product name
- 2-Aminopyrimidine-5-boronic acid
- Purity
- ≥95.0%
- Packaging
- 250mg
- Price
- $66.3
- Updated
- 2026/04/30
- Product number
- 706221
- Product name
- 2-Aminopyrimidine-5-boronic acid
- Purity
- ≥95.0%
- Packaging
- 1g
- Price
- $246
- Updated
- 2026/04/30
- Product number
- A2900
- Product name
- 2-Aminopyrimidine-5-boronic Acid (contains varying amounts of Anhydride)
- Packaging
- 1g
- Price
- $51
- Updated
- 2026/04/30
- Product number
- A629258
- Product name
- 2-Aminopyrimidine-5-boronic acid
- Packaging
- 100mg
- Price
- $45
- Updated
- 2021/12/16
- Product number
- A629258
- Product name
- 2-Aminopyrimidine-5-boronic acid
- Packaging
- 500mg
- Price
- $60
- Updated
- 2021/12/16
2-Amino-pyrimidine-5-boronic acid Chemical Properties,Usage,Production
Uses
2-Aminopyrimidine-5-boronic acid is used as pharmaceutical intermediates.
Uses
May contain varying amounts of anhydride
Synthesis
883231-25-2
936250-22-5
Example 17 Synthesis of 2-aminopyrimidin-5-ylboronic acid III: [2-[(tert-butoxycarbonyl)amino]pyrimidin-5-yl]boronic acid (40.0 kg, 49 wt%, HPLC purity 82.0 mol) was dissolved in water (245 kg), and concentrated hydrochloric acid (39.6 L) was added slowly while keeping the temperature below 30°C. The reaction mixture was stirred for 12 hours and then cooled to 10°C. Subsequently, the pH of the mixture was adjusted to 6.5 with 50% aqueous sodium hydroxide solution while controlling the temperature below 15 °C and stirring was continued for 1 hour. After adding water (69.0 kg), the mixture was aged for 30 minutes. The resulting slurry was filtered and the filter cake was dried under vacuum at 50 °C to afford the target product 2-aminopyrimidin-5-ylboronic acid III (10.2 kg, 90% yield). The structure of the product was confirmed by 1H NMR (300 MHz, DMSO-d6): δ 8.50 (s, 2H), 7.97 (s, 2H), 6.74 (s, 2H).
References
[1] Patent: US2014/100366, 2014, A1. Location in patent: Page/Page column
2-Amino-pyrimidine-5-boronic acid Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 2-Amino-pyrimidine-5-boronic acid manufacturers
- Product
- 2-Amino-pyrimidine-5-boronic acid 936250-22-5
- Price
- US $0.00/kg
- Min. Order
- 1kg
- Purity
- 98%
- Supply Ability
- 1000kg
- Release date
- 2025-07-08
- Product
- 2-Amino-pyrimidine-5-boronic acid 936250-22-5
- Price
- US $0.00-0.00/KG
- Min. Order
- 1KG
- Purity
- 98%
- Supply Ability
- 1Ton
- Release date
- 2022-10-13
- Product
- 2-Amino-pyrimidine-5-boronic acid 936250-22-5
- Price
- US $0.00-0.00/kg
- Min. Order
- 1kg
- Purity
- 98.0%
- Supply Ability
- 1000kg
- Release date
- 2023-04-05