ChemicalBook > CAS DataBase List > 2-Amino-pyrimidine-5-boronic acid

2-Amino-pyrimidine-5-boronic acid

Product Name
2-Amino-pyrimidine-5-boronic acid
CAS No.
936250-22-5
Chemical Name
2-Amino-pyrimidine-5-boronic acid
Synonyms
>=95.0%;Minimum purity 95.0%;2-Amino-5-boronopyrimidine;2-AMinopyriMidine-5-boronic;2-Aminopyrimidine-5-boron...;2-Aminopyrimidine-5-boronicaci;2-aMino-4-pyMidine boronic acid;2-AMino-5-pyriMidineboronic acid;2-Aminopyrimidine-5-boronic acid;2-Aminopyrimidine-5-ylboronic acid
CBNumber
CB31113135
Molecular Formula
C4H6BN3O2
Formula Weight
138.92
MOL File
936250-22-5.mol
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2-Amino-pyrimidine-5-boronic acid Property

Melting point:
206-211 °C
Boiling point:
487.0±55.0 °C(Predicted)
Density 
1.44±0.1 g/cm3(Predicted)
storage temp. 
2-8°C
solubility 
DMSO (Slightly, Heated), Methanol (Slightly, Heated)
form 
Solid
pka
2.58±0.11(Predicted)
color 
Off-White
Stability:
Hygroscopic
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Safety

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
26-36/37/39
WGK Germany 
2
HS Code 
2933599590
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
706221
Product name
2-Aminopyrimidine-5-boronic acid
Purity
≥95.0%
Packaging
250mg
Price
$43.61
Updated
2025/07/31
Sigma-Aldrich
Product number
706221
Product name
2-Aminopyrimidine-5-boronic acid
Purity
≥95.0%
Packaging
1g
Price
$231
Updated
2025/07/31
TCI Chemical
Product number
A2900
Product name
2-Aminopyrimidine-5-boronic Acid (contains varying amounts of Anhydride)
Packaging
1g
Price
$76
Updated
2025/07/31
TRC
Product number
A629258
Product name
2-Aminopyrimidine-5-boronic acid
Packaging
100mg
Price
$45
Updated
2021/12/16
TRC
Product number
A629258
Product name
2-Aminopyrimidine-5-boronic acid
Packaging
500mg
Price
$60
Updated
2021/12/16
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2-Amino-pyrimidine-5-boronic acid Chemical Properties,Usage,Production

Uses

2-Aminopyrimidine-5-boronic acid is used as pharmaceutical intermediates.

Uses

May contain varying amounts of anhydride

Synthesis

883231-25-2

936250-22-5

Example 17 Synthesis of 2-aminopyrimidin-5-ylboronic acid III: [2-[(tert-butoxycarbonyl)amino]pyrimidin-5-yl]boronic acid (40.0 kg, 49 wt%, HPLC purity 82.0 mol) was dissolved in water (245 kg), and concentrated hydrochloric acid (39.6 L) was added slowly while keeping the temperature below 30°C. The reaction mixture was stirred for 12 hours and then cooled to 10°C. Subsequently, the pH of the mixture was adjusted to 6.5 with 50% aqueous sodium hydroxide solution while controlling the temperature below 15 °C and stirring was continued for 1 hour. After adding water (69.0 kg), the mixture was aged for 30 minutes. The resulting slurry was filtered and the filter cake was dried under vacuum at 50 °C to afford the target product 2-aminopyrimidin-5-ylboronic acid III (10.2 kg, 90% yield). The structure of the product was confirmed by 1H NMR (300 MHz, DMSO-d6): δ 8.50 (s, 2H), 7.97 (s, 2H), 6.74 (s, 2H).

References

[1] Patent: US2014/100366, 2014, A1. Location in patent: Page/Page column

2-Amino-pyrimidine-5-boronic acid Preparation Products And Raw materials

Raw materials

Preparation Products

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2-Amino-pyrimidine-5-boronic acid Suppliers

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View Lastest Price from 2-Amino-pyrimidine-5-boronic acid manufacturers

Shaanxi Dideu New Materials Co. Ltd
Product
2-Amino-pyrimidine-5-boronic acid 936250-22-5
Price
US $0.00/kg
Min. Order
1kg
Purity
98%
Supply Ability
1000kg
Release date
2025-07-08
Henan Aochuang Chemical Co.,Ltd.
Product
2-Amino-pyrimidine-5-boronic acid 936250-22-5
Price
US $0.00-0.00/KG
Min. Order
1KG
Purity
98%
Supply Ability
1Ton
Release date
2022-10-13
LY Global chemicals co.,ltd .
Product
2-Amino-pyrimidine-5-boronic acid 936250-22-5
Price
US $0.00-0.00/kg
Min. Order
1kg
Purity
98.0%
Supply Ability
1000kg
Release date
2023-04-05

936250-22-5, 2-Amino-pyrimidine-5-boronic acidRelated Search:

2-Morpholinopyrimidin-5-ylboronic acid 2-Amino-pyrimidine-5-boronic acid 2-Aminopyrimidine-5-boronic Acid Pinacol Ester 2-Aminopyrimidine 2-(4-MORPHOLINO)PYRIMIDINE-5-BORONIC ACID PINACOL ESTER [2-(2,5-DIMETHYL-1H-PYRROL-1-YL)PYRIMIDIN-5-YL]BORONIC ACID 2-(PIPERIDIN-1-YL)PYRIMIDINE-5-BORONIC ACID PINACOL ESTER 2-Dimethylamino-pyrimidine-5-boronic acid pinacol ester 1-[5-(4,4,5,5-TETRAMETHYL-[1,3,2]DIOXABOROLAN-2-YL)-PYRIMIDIN-2-YL]-PIPERIDINE-4-CARBOXYLIC ACID (2-[(2-METHOXYETHYL)AMINO]PYRIMIDIN-5-YL)BORONIC ACID (2-PIPERIDIN-1-YLPYRIMIDIN-5-YL)BORONIC ACID (2-PIPERAZIN-1-YLPYRIMIDIN-5-YL)BORONIC ACID [2-(BENZYLAMINO)PYRIMIDIN-5-YL]BORONIC ACID (2-[(4-METHOXYBENZOYL)AMINO]PYRIMIDIN-5-YL)BORONIC ACID (2-([3-(1H-IMIDAZOL-1-YL)PROPYL]AMINO)PYRIMIDIN-5-YL)BORONIC ACID 1-[5-(DIHYDROXYBORYL)PYRIMIDIN-2-YL]PIPERIDINE-3-CARBOXYLIC ACID 1-[5-(4,4,5,5-TETRAMETHYL-[1,3,2]DIOXABOROLAN-2-YL)-PYRIMIDIN-2-YL]-1H-PYRROLE-2-CARBALDEHYDE 2-(4-[5-(4,4,5,5-TETRAMETHYL-[1,3,2]DIOXABOROLAN-2-YL)-PYRIMIDIN-2-YL]-PIPERAZIN-1-YL)-ETHANOL

  • 2-Aminopyrimidine-5-boronic acid
  • 2-Aminopyrimidine-5-ylboronic acid
  • 2-aminopyrimidin-5-yl-5-boronic acid
  • (2-amino-5-pyrimidinyl)boronic acid
  • 2-Aminopyrimidine-5-boron...
  • 2-AMinopyriMidine-5-boronic
  • 2-Amino-5-boronopyrimidine
  • 2-AMino-5-pyriMidineboronic acid
  • 2-aMino-4-pyMidine boronic acid
  • >=95.0%
  • 2-Aminopyrimidine-5-boronic acid >=95.0%
  • (2-aminopyrimidin-5-yl)boronic acid, 2-amino-pyrimidine-5-boronic acid, 2-aminopyrimidin-5-ylboronic acid, 2-aminopyrimidine-5-boronic acid, 2-amino-5-pyrimidylboronic acid, 2-amino-pyrimidin-5-yl-boronic acid, pyrimidin-2-ylamine-4-boronic acid
  • 2-Aminopyrimidine-5-boronic Acid (contains varying amounts of Anhydride)
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  • Minimum purity 95.0%
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  • StandardMixtureofn-Paraffins(consistsofC17,C18,C19andC20)[StandardMaterialforGC]&gt
  • Galβ(1-3)GalNAcβ(1-3)Galα(1-4)Galβ(1-4)Glc-β-pNP &gt
  • Neu5Ac[1Me,4789Ac]α(2-6)Gal[24Bz,3Bn]-β-MP &gt
  • Boronic acid, B-(2-amino-5-pyrimidinyl)-
  • 2-Aminopyrimidine-5-boronicaci
  • 2-Amino-pyrimidine-5-boronic acid ISO 9001：2015 REACH
  • 2-Aminopyrimidine-5-boronic acid - [A0080]
  • 936250-22-5
  • Organic boronic acid