Sodium 4-Aminophenylarsonate
- Product Name
- Sodium 4-Aminophenylarsonate
- CAS No.
- 127-85-5
- Chemical Name
- Sodium 4-Aminophenylarsonate
- Synonyms
- soamin;sonate;ATOXYL;arsamin;nuarsol;protoxyl;trypoxyl;nci-c61176;Chebi:36049;arsinosolvin
- CBNumber
- CB3111606
- Molecular Formula
- C6H6AsNNa2O3
- Formula Weight
- 261.02
- MOL File
- 127-85-5.mol
Sodium 4-Aminophenylarsonate Property
- Water Solubility
- Soluble in water
- form
- powder to crystal
- color
- Tetrahydrate: white, crystalline powder
- Odor
- odorless
- Merck
- 14,8578
- EPA Substance Registry System
- Sodium arsanilate (127-85-5)
Safety
- Risk Statements
- 26/27/28
- Safety Statements
- 26-36/37/39
- RIDADR
- 2473
- RTECS
- CF9625000
- HS Code
- 2920.90.2000
- HazardClass
- 6.1(b)
- PackingGroup
- III
- Hazardous Substances Data
- 127-85-5(Hazardous Substances Data)
- Toxicity
- LD50 scu-rat: 75 mg/kg BIZEA2 184,360,27
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Danger
- Hazard statements
-
H301Toxic if swalloed
H331Toxic if inhaled
H350May cause cancer
H400Very toxic to aquatic life
H410Very toxic to aquatic life with long lasting effects
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P270Do not eat, drink or smoke when using this product.
P271Use only outdoors or in a well-ventilated area.
P273Avoid release to the environment.
P301+P310IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.
P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P311Call a POISON CENTER or doctor/physician.
P321Specific treatment (see … on this label).
P330Rinse mouth.
P391Collect spillage. Hazardous to the aquatic environment
P403+P233Store in a well-ventilated place. Keep container tightly closed.
P405Store locked up.
P501Dispose of contents/container to..…
N-Bromosuccinimide Price
- Product number
- A0531
- Product name
- Sodium 4-Aminophenylarsonate
- Packaging
- 25G
- Price
- $71
- Updated
- 2024/03/01
- Product number
- S612008
- Product name
- Sodium 4-Aminophenylarsonate
- Packaging
- 250mg
- Price
- $45
- Updated
- 2021/12/16
- Product number
- 37556
- Product name
- Sodium4-aminophenylarsonate,98%(Assaybytitration,HPLC)
- Purity
- 98%(Assaybytitration,HPLC)
- Packaging
- 25G
- Price
- $68.32
- Updated
- 2021/12/16
- Product number
- 8978AL
- Product name
- Sodium 4-Aminophenylarsonate
- Packaging
- 25g
- Price
- $147
- Updated
- 2021/12/16
- Product number
- ING0004909
- Product name
- SODIUM ARSANILATE
- Purity
- 95.00%
- Packaging
- 25G
- Price
- $1114.7
- Updated
- 2021/12/16
Sodium 4-Aminophenylarsonate Chemical Properties,Usage,Production
Definition
ChEBI: Sodium arsanilate is an organoarsonic acid salt and an organic sodium salt. It has a role as an antisyphilitic drug. It contains an arsanilate(1-).
General Description
A white crystalline, odorless powder. Slightly denser than water. Contact may irritate skin, eyes, and mucous membranes. May be toxic by ingestion. Used to make other chemicals.
Air & Water Reactions
Soluble in water.
Health Hazard
TOXIC; inhalation, ingestion or skin contact with material may cause severe injury or death. Contact with molten substance may cause severe burns to skin and eyes. Avoid any skin contact. Effects of contact or inhalation may be delayed. Fire may produce irritating, corrosive and/or toxic gases. Runoff from fire control or dilution water may be corrosive and/or toxic and cause pollution.
Fire Hazard
Non-combustible, substance itself does not burn but may decompose upon heating to produce corrosive and/or toxic fumes. Some are oxidizers and may ignite combustibles (wood, paper, oil, clothing, etc.). Contact with metals may evolve flammable hydrogen gas. Containers may explode when heated.
Pharmaceutical Applications
Bechamp,teaching medicinal chemistry at the University of Montpellier, synthesised in 1863 a compound from aniline and arsenic acid, which became known later as Atoxyl. The name Atoxyl stems from its decreased toxicity. Bechamp characterised his compound as an anilide.
In 1905, Thomas and Breinl showed that Atoxyl was effective in the treatment of trypanosomas, mainly Trypanosoma brucei gambiense-the cause of the African sleeping sickness, which was the main health problem around that time in Africa. Nevertheless, very high doses were required to show any pronounced effect, and as a result severe side effects such as blindness and damage to the optical nerve were common issues.
Inspired by this research, Ehrlich hired the chemist Bertheim in 1905. Bertheim revised the structure of Atoxyl and the correct chemical formula was assigned. Atoxyl was identified as an p-anilinyl arsenic acid derivative on the basis of its properties to reduce Tollen’s reagent [Ag(NH3)2]+ to metallic silver and its potential use to synthesise the corresponding diazo dye.
Safety Profile
Poison by subcutaneous route. Can cause blindness. When heated to decomposition it emits very toxic fumes of As and NOx.
Sodium 4-Aminophenylarsonate Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from Sodium 4-Aminophenylarsonate manufacturers
- Product
- Sodium 4-Aminophenylarsonate 127-85-5
- Price
- US $1.10/g
- Min. Order
- 1g
- Purity
- 99.9%
- Supply Ability
- 100 Tons min
- Release date
- 2021-08-17