ChemicalBook > CAS DataBase List > 1-(Diphenylmethyl)-3-azetidinyl methanesulfonate

1-(Diphenylmethyl)-3-azetidinyl methanesulfonate

Product Name
1-(Diphenylmethyl)-3-azetidinyl methanesulfonate
CAS No.
33301-41-6
Chemical Name
1-(Diphenylmethyl)-3-azetidinyl methanesulfonate
Synonyms
1-BENZHYDRYLAZETIDIN-3-YL METHANESULFONATE;BUTTPARK 37\04-14;1-BENZHYDRYL-3-METHANESULFONATOAZETIDINE;1-(Diphenylmethyl)-3-(mesyloxy)azetidine;1-BENZHYDRYL-3-METHANESULFONYLOXY AZETIDINE;1-Benzhydryl-3-methanesulphonyloxyazetidine;1-BENZHYDRYL-3-METHANESULFONATOAZETIDINE 98%;1-Benzhydryl-3-azetidinylMethanesulfonate>1-BENZHYDRYL-3-METHANESULFONATOAZETIDINE CAS;1-DIPHENYLMETHYL-3-AZETIDINYL METHANESULFONATE
CBNumber
CB3111828
Molecular Formula
C17H19NO3S
Formula Weight
317.4
MOL File
33301-41-6.mol
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1-(Diphenylmethyl)-3-azetidinyl methanesulfonate Property

Melting point:
111-112°C
Boiling point:
459.9±34.0 °C(Predicted)
Density 
1.28±0.1 g/cm3(Predicted)
storage temp. 
Sealed in dry,Room Temperature
solubility 
Dichloromethane, Ether, Ethyl Acetate, Methanol
form 
Solid
pka
5.67±0.10(Predicted)
color 
White
InChI
InChI=1S/C17H19NO3S/c1-22(19,20)21-16-12-18(13-16)17(14-8-4-2-5-9-14)15-10-6-3-7-11-15/h2-11,16-17H,12-13H2,1H3
InChIKey
MSVZMUILYMLJCF-UHFFFAOYSA-N
SMILES
N1(C(C2=CC=CC=C2)C2=CC=CC=C2)CC(OS(C)(=O)=O)C1
CAS DataBase Reference
33301-41-6(CAS DataBase Reference)
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Safety

Safety Statements 
24/25
HazardClass 
IRRITANT
HS Code 
29339900
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P405Store locked up.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
S906700
Product name
1-(DIPHENYLMETHYL)-3-AZETIDINYL METHANESULFONATE
Purity
Aldrich
Packaging
50mg
Price
$29.8
Updated
2024/03/01
TCI Chemical
Product number
D4131
Product name
1-Benzhydryl-3-azetidinyl Methanesulfonate
Purity
>95.0%(HPLC)(T)
Packaging
1g
Price
$205
Updated
2023/06/20
Alfa Aesar
Product number
H57822
Product name
1-Benzhydryl-3-azetidinyl methanesulfonate, 95%
Packaging
500mg
Price
$18.4
Updated
2022/04/27
Alfa Aesar
Product number
H57822
Product name
1-Benzhydryl-3-azetidinyl methanesulfonate, 95%
Packaging
250mg
Price
$13.5
Updated
2021/12/16
TRC
Product number
B196875
Product name
1-Benzhydryl-3-methanesulfonatoazetidine
Packaging
10g
Price
$45
Updated
2021/12/16
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1-(Diphenylmethyl)-3-azetidinyl methanesulfonate Chemical Properties,Usage,Production

Chemical Properties

White Crystalline Solid

Uses

A proline analog and proline formation inhibitor

Synthesis

Preparation procedure of 1-(Diphenylmethyl)-3-azetidinyl methanesulfonate: To a reaction flask was charged 632 g (2.64 mol) of 1-benzhydrylazetidin- 3-ol, acetonitrile (1.9 L), and triethylamine (601 g, 1.5 equiv). The mixture was cooled in an ice-acetone bath (-5 °C). Methanesulfonyl chloride (436 g, 1.20 equiv) was added via a drop funnel while keeping the reaction temperature at less than5 °C. HPLC showed reaction completion after 15 min. Water (6.3 L) was added, and the reaction mixture was stirred for 2 h at room temperature and filtered. The filter cake was rinsed with water (2 x 1 L), pulled dry under vacuum, and directly subjected to the amination reaction in the next step. Yield 100%.

1-(Diphenylmethyl)-3-azetidinyl methanesulfonate Preparation Products And Raw materials

Raw materials

Preparation Products

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1-(Diphenylmethyl)-3-azetidinyl methanesulfonate Suppliers

Xianning Shen Lan Biomedical Research and Development Co., Ltd.
Tel
18171815831
Email
1341138380@qq.com
Country
China
ProdList
2769
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58
Shanghai Jianchao Biotechnology Co., LTD
Tel
86-1801738-3231 13621743886
Email
3366408901@qq.com
Country
China
ProdList
3821
Advantage
58
J & K SCIENTIFIC LTD.
Tel
010-82848833 400-666-7788
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
96815
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76
PharmaBlock Sciences (Nanjing),Inc.
Tel
400-0255188 4000255188
Fax
86-025-86918232
Email
sales@pharmablock.com
Country
China
ProdList
4986
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55
3B Pharmachem (Wuhan) International Co.,Ltd.
Tel
821-50328103-801 18930552037
Fax
86-21-50328109
Email
3bsc@sina.com
Country
China
ProdList
15848
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Chembest Research Laboratories Limited
Tel
021-20908456
Fax
021-58180499
Email
sales@BioChemBest.com
Country
China
ProdList
6011
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61
Alfa Aesar
Tel
400-6106006
Fax
021-67582001/03/05
Email
saleschina@alfa-asia.com
Country
China
ProdList
30132
Advantage
84
TCI (Shanghai) Development Co., Ltd.
Tel
021-67121386
Fax
021-67121385
Email
Sales-CN@TCIchemicals.com
Country
China
ProdList
24539
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81
Ark Pharm, Inc.
Tel
847-367-3680
Fax
847-367-3681
Email
sales@arkpharminc.com
Country
United States
ProdList
1670
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56
Energy Chemical
Tel
021-021-58432009 400-005-6266
Fax
021-58436166
Email
sales8178@energy-chemical.com
Country
China
ProdList
44751
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View Lastest Price from 1-(Diphenylmethyl)-3-azetidinyl methanesulfonate manufacturers

Henan Fengda Chemical Co., Ltd
Product
1-(Diphenylmethyl)-3-azetidinyl methanesulfonate 33301-41-6
Price
US $31.00-1.50/kg
Min. Order
1kg
Purity
99%
Supply Ability
g-kg-tons, free sample is available
Release date
2024-04-10
Zhuozhou Wenxi import and Export Co., Ltd
Product
1-(Diphenylmethyl)-3-azetidinyl methanesulfonate 33301-41-6
Price
US $15.00-10.00/KG
Min. Order
1KG
Purity
99%+ HPLC
Supply Ability
Monthly supply of 1 ton
Release date
2021-07-10
Zhuozhou Wenxi import and Export Co., Ltd
Product
1-(Diphenylmethyl)-3-azetidinyl methanesulfonate 33301-41-6
Price
US $15.00-10.00/KG
Min. Order
1KG
Purity
99%+ HPLC
Supply Ability
Monthly supply of 1 ton
Release date
2021-07-09

33301-41-6, 1-(Diphenylmethyl)-3-azetidinyl methanesulfonateRelated Search:


  • BUTTPARK 37\04-14
  • 1-BENZHYDRYL-3-METHANESULFONATOAZETIDINE
  • 1-BENZHYDRYL-3-METHANESULFONYLOXY AZETIDINE
  • 1-BENZHYDRYLAZETIDIN-3-YL METHANESULFONATE
  • 1-(DIPHENYLMETHYL)-3-(METHANESULFONYLOXY)AZETIDINE
  • 1-DIPHENYLMETHYL-3-AZETIDINYL METHANESULFONATE
  • 1-(diphenylmethyl)-3-(methanesulfonyloxy)azetinide
  • 1-Diphenylmethyl-3-azetidinyl Methanethiosulfonate
  • 1-Benzhydryl-3-methanesulphonyloxyazetidine
  • 1-BENZHYDRYL-3-METHANESULFONATOAZETIDINE 98%
  • Methanesulfonic acid 1-benzhydryl-azetidin-3-yl ester
  • 1-(Diphenylmethyl)-3-(mesyloxy)azetidine
  • 1-(Diphenylmethyl)-3-[(methylsulfonyl)oxy]azetidine
  • 1-(Diphenylmethyl)azetidin-3-yl methanesulfonate
  • 1-Benzhydryl-3-azetidinyl Methanesulfonate, 95%
  • methanesulfonic acid [1-[di(phenyl)methyl]-3-azetidinyl] ester
  • 1-Benzhydrylazetidin-3-yl methanesulfonate 97%
  • methanesulfonic acid [1-[di(phenyl)methyl]azetidin-3-yl] ester
  • (1-benzhydryl-2-hydroxyazetidin-3-yl)methanesulfonate
  • 1-(Diphenylmethyl)-3-azetidinyl methanesulfonate 95%
  • 1-(Diphenylmethyl)-3-azetidinyl methanesulfote
  • 1-Benzhydryl-3-azetidinylMethanesulfonate&gt
  • 3-Azetidinol, 1-(diphenylmethyl)-, 3-methanesulfonate
  • 1-BENZHYDRYL-3-METHANESULFONATOAZETIDINE CAS
  • 1-(Diphenylmethyl) azitidine-3-yl methane sulfonate
  • Methane Sulphonic acid 1-Bezhydryl Azetidine 3-yl Ester
  • 33301-41-6
  • 3301-41-6
  • C17H19NO3S
  • Aromatics
  • Heterocycles
  • MTS & Sulfhydryl Active Reagents