Gadobutrol

Product Name: Gadobutrol
CAS No.: 138071-82-6
Chemical Name: Gadobutrol
Synonyms: CL124;CS-113;gudobutrol;Gadobutrol;Gsdobutrol;Ggadobutrol;Gadobutrol Monomer;gadolinium butanol;Gadolinium cloth alcohol;Lansoprazole Impurity 76
CBNumber: CB31118291
Molecular Formula: C18H31N4O9.Gd
Formula Weight: 604.712
MOL File: 138071-82-6.mol

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Gadobutrol Property

Melting point:: >264°C (dec.)
Density: 1.3 g/mL at 37 °C
storage temp.: Refrigerator
solubility: Water (Slightly)
form: Solid
color: White to Off-White
PH: 6.6-8
InChIKey: ZPDFIIGFYAHNSK-IWEVFNEWNA-K
SMILES: N1(CCN(CC([O-])=O)CCN(CC([O-])=O)CCN(CC([O-])=O)CC1)[C@H](CO)[C@H](O)CO.[Gd+3] |&1:24,27,r|

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Safety

Toxicity: LD50 i.v. in mice: 23 mmol/kg (Vogler)

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Usbiological

Product number: 451035
Product name: Gadobutrol
Packaging: 250mg
Price: $355
Updated: 2021/12/16

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Gadobutrol Chemical Properties,Usage,Production

Description

Gadobutrol is a nonionic, paramagnetic contrast agent developed for tissue contrast enhancement in magnetic resonance imaging (MRI). It has a macrocyclic framework and is neutral. It is a water-soluble, highly hydrophilic compound with a partition coefficient between n-butanol and buffer at pH 7.6 of ~ 0.006.

Uses

Gadobutrol is a gadolinium-based MRI contrast agent (GBCA).

Uses

Gadobutrol injection is a magnetic resonance imaging (MRI) contrast agent that is used to help create a clear picture of the body during an MRI scan. MRI scans are a special kind of procedure that lets a doctor look at the inside of the body, such as the brain.

brand name

Gadobutrol is marketed by Bayer AG as Gadovist, and by Bayer HealthCare Pharmaceuticals as Gadavist. In India, it is also marketed by Vivere Imaging as Viv-butrol.

Mechanism of action

In the central nervous system, Gadobutrol works by highlighting any areas with disrupted blood brain barrier (BBB) and/or abnormal vascularity. In breast tissue, Gadobutrol exposes the presence and extent of malignant breast disease.

Side effects

Side effects of Gadobutrol are uncommon but may include: headache, nausea, vomiting, feeling unwell (malaise), dizziness, abnormal or unpleasant taste in your mouth, feeling hot, numbness or tingly feeling, itching or rash, skin redness, or injection site reactions (cold feeling, warmth, pain, or burning). Its more serious side effects include: urinating less than usual or not at all; drowsiness, confusion, mood changes, increased thirst, loss of appetite; swelling, weight gain, shortness of breath; seizures (convulsions); breathing problems; pounding heartbeats or fluttering in your chest; or severe pain, burning, or irritation around the IV needle.

Dosage

Gadobutrol is given as an infusion into a vein. The recommended dose of Gadobutrol for adult and pediatric patients (including term neonates) is 0.1 mL/kg body weight (0.1 mmol/kg).

Waste Disposal

Expired or waste pharmaceuticals shall carefully take into consideration applicable DEA, EPA, and FDA regulations. It is not appropriate to dispose by flushing the pharmaceutical down the toilet or discarding to trash. If possible return the pharmaceutical to the manufacturer for proper disposal being careful to properly label and securely package the material. Alternatively, the waste pharmaceutical shall be labeled, securely packaged and transported by a state licensed medical waste contractor to dispose by burial in a licensed hazardous or toxic waste landfill or incinerator.

Gadobutrol Preparation Products And Raw materials

Raw materials

Preparation Products

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Gadobutrol Suppliers

China 174 Germany 1 India 5 United Kingdom 1 United States 8 Global 189

BOC Sciences

Tel: 16314854226; +16314854226
Email: inquiry@bocsci.com
Country: United States
ProdList: 19741
Advantage: 58

Cckinase, Inc.

Tel: +1 (732)236-3202
Email: sales@cckinase.com
Country: United States
ProdList: 2738
Advantage: 58

Alchem Pharmtech,Inc.

Tel: 8485655694
Email: sales@alchempharmtech.com
Country: United States
ProdList: 63687
Advantage: 58

Aladdin Scientific

Tel: +1-+1(833)-552-7181
Email: sales@aladdinsci.com
Country: United States
ProdList: 57505
Advantage: 58

Protheragen-ING

Tel: +16313385890
Email: info@protheragen-ing.com
Country: United States
ProdList: 3868
Advantage: 58

United States Biological

Tel: --
Fax: --
Email: chemicals@usbio.net
Country: United States
ProdList: 6214
Advantage: 80

2A PharmaChem USA

Tel: --
Fax: --
Email: sales@2apharmachem.com
Country: United States
ProdList: 6137
Advantage: 39

3B Scientific Corporation

Tel: --
Fax: --
Email: sales@3bsc.com
Country: United States
ProdList: 6718
Advantage: 47

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View Lastest Price from Gadobutrol manufacturers

Henan Fengda Chemical Co., Ltd

Product: Gadobutrol 138071-82-6
Price: US $8.00-1.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: g-kg-tons, free sample is available
Release date: 2024-04-09

Hebei Mingeng Biotechnology Co., Ltd

Product: Gadobutrol 138071-82-6
Price: US $200.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 1000kg/Month
Release date: 2022-11-28

Changzhou Rokechem Technology Co., Ltd.

Product: Gadobutrol 138071-82-6
Price: US $0.00-0.00/KG
Min. Order: 1KG
Purity: ≥98%
Supply Ability: 1-1000KGS
Release date: 2022-11-14

138071-82-6, GadobutrolRelated Search:

Sodium edetate Meglumine Gadoteridol Cyclen Gadobutrol 1,1,4,7,10,10-HEXAMETHYLTRIETHYLENETETRAMINE

Gadobutrol

GadoliniuM,[10-[2,3-dihydroxy-1-(hydroxyMethyl)propyl]-1,4,7,10-tetraazacyclododecane-1,4,7-triacetato(3-)-kN1,kN4,kN7,kN10,kO1,kO4,kO7]-

gallium 10-(1,3,4-trihydroxybutan-2-yl)-1,4,7,10-tetraazacyclododecane-1,4,7-tricarboxylate

CL124

gadolinium(III) 2,2',2''-(10-((2R,3S)-1,3,4-trihydroxybutan-2-yl)-1,4,7,10-tetraazacyclododecane-1,4,7-triyl)triacetate

CS-113

gudobutrol

Ggadobutrol

Gsdobutrol

Gadolinium cloth alcohol

Gadobutrol Monomer

gadolinium butanol

Lansoprazole Impurity 76

138071-82-6

C18H31GdN4O9

C18H31GaN4O9

API