ChemicalBook > CAS DataBase List > 3-Hydroxyglutaric Acid

3-Hydroxyglutaric Acid

Product Name: 3-Hydroxyglutaric Acid
CAS No.: 638-18-6
Chemical Name: 3-Hydroxyglutaric Acid
Synonyms: b-Hydroxyglutaric Aci;3-Hydroxyglutaric Acid;2,4-Dideoxypentaric Acid;3-Hydroxy-pentanedioic Acid;Pentanedioic acid,3-hydroxy-;3-Hydroxyglutaric acid,Endogenous Metabolite,3 Hydroxyglutaric acid,inhibit,Inhibitor,3Hydroxyglutaric acid
CBNumber: CB31175748
Molecular Formula: C5H8O5
Formula Weight: 148.11
MOL File: 638-18-6.mol

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3-Hydroxyglutaric Acid Property

Melting point:: 94-96°C
Boiling point:: 365.0±32.0 °C(Predicted)
Density: 1.508±0.06 g/cm3(Predicted)
storage temp.: -20°C Freezer
solubility: Methanol (Slightly), Water (Slightly)
form: Solid
pka: 3.93±0.10(Predicted)
color: White to Pale Orange
InChI: InChI=1S/C5H8O5/c6-3(1-4(7)8)2-5(9)10/h3,6H,1-2H2,(H,7,8)(H,9,10)
InChIKey: ZQHYXNSQOIDNTL-UHFFFAOYSA-N
SMILES: C(O)(=O)CC(O)CC(O)=O

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P321Specific treatment (see … on this label).

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P362Take off contaminated clothing and wash before reuse.

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N-Bromosuccinimide Price

Cayman Chemical

Product number: 16334
Product name: 3-Hydroxyglutaric Acid
Purity: ≥95%
Packaging: 1mg
Price: $36
Updated: 2024/03/01

Cayman Chemical

Product number: 16334
Product name: 3-Hydroxyglutaric Acid
Purity: ≥95%
Packaging: 5mg
Price: $117
Updated: 2024/03/01

Cayman Chemical

Product number: 16334
Product name: 3-Hydroxyglutaric Acid
Purity: ≥95%
Packaging: 10mg
Price: $162
Updated: 2024/03/01

Cayman Chemical

Product number: 16334
Product name: 3-Hydroxyglutaric Acid
Purity: ≥95%
Packaging: 25mg
Price: $357
Updated: 2024/03/01

TRC

Product number: H942580
Product name: 3-HydroxyglutaricAcid
Packaging: 50mg
Price: $795
Updated: 2021/12/16

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3-Hydroxyglutaric Acid Chemical Properties,Usage,Production

Chemical Properties

Off-White to Light Pink Solid

Uses

3-Hydroxyglutaric Acid (cas# 638-18-6) is a compound useful in organic synthesis.

Definition

ChEBI: 3-hydroxyglutaric acid is a 3 hydroxy carboxylic acid that is glutaric acid which is substituted by a hydroxy group at position 3. It is a diagnostic marker for glutaric aciduria type I. It has a role as a human urinary metabolite and a human blood serum metabolite. It is a 3-hydroxy carboxylic acid and an alpha,omega-dicarboxylic acid. It is functionally related to a glutaric acid. It is a conjugate acid of a 3-hydroxyglutarate(2-).

Biological Activity

3-Hydroxyglutaric acid is a glutaric acid derivative which is the byproduct of glutaric acidemia type I. Glutaric aciduria type I (glutaryl-CoA dehydrogenase deficiency) is an inborn error of metabolism th at usually manifests in infancy by an acute encephalopathic crisis and often results in permanent motor handicap. Studies indicate th at 3-hydroxyglutaric acid can be used as biomarker for GCDH (glutaryl-CoA dehydrogenase) deficiency. It is believed th at the excretion of 3-hydroxyglutaric acid is increased during ketosis, which occurs during glutaryl-CoA dehydrogenase deficiency. Studies on striatal cultures show th at IGF-1 and FGF-2 (bFGF) reduces 3-hydroxyglutaric acid toxicity in striatal neurons.

IC 50

Human Endogenous Metabolite

3-Hydroxyglutaric Acid Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from 3-Hydroxyglutaric Acid manufacturers

Henan Aochuang Chemical Co.,Ltd.

Product: 3-Hydroxyglutaric Acid 638-18-6
Price: US $0.00-0.00/kg
Min. Order: 1kg
Purity: 98%
Supply Ability: 1Ton
Release date: 2022-09-28

Career Henan Chemical Co

Product: 3-Hydroxyglutaric Acid 638-18-6
Price: US $1.00/KG
Min. Order: 1KG
Purity: 98%
Supply Ability: 200kg
Release date: 2019-08-30

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638-18-6

HOOCCD2CDOHCD2COOH

Aliphatics