Alverine citrate

Product Name: Alverine citrate
CAS No.: 5560-59-8
Chemical Name: Alverine citrate
Synonyms: GaMatran;CalMabel;Spacolin;SpasMona;NSC 35459;Profenine;Prophelan;Proverine;AntispasMin;SpasMaverine
CBNumber: CB3303160
Molecular Formula: C26H35NO7
Formula Weight: 473.57
MOL File: 5560-59-8.mol

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Alverine citrate Property

Melting point:: 100-102°
storage temp.: 2-8°C
solubility: Slightly soluble in water and in methylene chloride, sparingly soluble in ethanol (96 per cent).
color: White to Off-White
InChIKey: RYHCACJBKCOBTJ-UHFFFAOYSA-N
CAS DataBase Reference: 5560-59-8(CAS DataBase Reference)

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Safety

Safety Statements: 24/25
WGK Germany: 3
HS Code: 29214990

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: Y0000687
Product name: Alverine citrate salt
Purity: European Pharmacopoeia (EP) Reference Standard
Packaging: y0000687
Price: $223
Updated: 2024/03/01

Sigma-Aldrich

Product number: A0424
Product name: Alverine citrate salt
Packaging: 5g
Price: $215.6
Updated: 2024/03/01

Cayman Chemical

Product number: 26892
Product name: Alverine (citrate)
Packaging: 1g
Price: $32
Updated: 2024/03/01

Cayman Chemical

Product number: 26892
Product name: Alverine (citrate)
Packaging: 5g
Price: $63
Updated: 2024/03/01

TRC

Product number: A575780
Product name: AlverineCitrate
Packaging: 10g
Price: $65
Updated: 2021/12/16

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Alverine citrate Chemical Properties,Usage,Production

Chemical Properties

White or almost white, crystalline powder.

Originator

Alverine citrate,Kemikos

Uses

Used for studies of pharmacological activity including:

Synergism with fluconazole against Saccharomyces cerevisiae and Candida albicans
Efficacy of combination with simeticone on abdominal pain associated with irritable bowel syndrome
Nutrient-sensitized screening for drugs that shift energy metabolism from mitochondrial respiration to glycolysis
Drug effects viewed from a signal transduction network perspective
Enhanced cytotoxic effect of proteasome inhibitor MG132
Mechanism of action on phasic smooth muscles

Uses

An adrenergic-β3 receptor agonist. Antispasmodic.

Uses

anticholinergic

Definition

ChEBI: The citrate salt of alverine, resulting from the reaction of equimolar amounts of alvarine and citric acid. An antispasmodic that acts directly on intestinal and uterine smooth muscle, it is used in the treatment of irritable bowel syndrome.

Manufacturing Process

2 Methods of producing of alverine:
1. 3-Phenylpropylchloride reacted with ethylamine in the presence potassium hydroxide and N-ethyl-3,3'-diphenyldipropylamine (alverine) was obtained.
2. 3-Phenylpropenal reacted with ethylamine in the presence hydrogen and Pt as catalyst and BaSO4 and N-ethyl-3,3'-diphenyldipropylamine (alverine) was obtained.
In practice it is usually used as citrate.

Therapeutic Function

Anticholinergic, Spasmolytic

Alverine citrate Preparation Products And Raw materials

Raw materials

Preparation Products

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Alverine citrate Suppliers

Canada 1 China 139 Europe 3 France 1 Germany 2 India 6 Japan 1 Slovakia 1 Switzerland 1 United Kingdom 3 United States 26 Global 184

YUANSHU PHARMACEUTICAL TECHNOLOGY CO.,LTD

Tel: 025-84823350转8002 18251967190
Fax: 025-84823632
Email: sales1@a-starchemical.com
Country: China
ProdList: 67
Advantage: 58

J & K SCIENTIFIC LTD.

Tel: 010-82848833 400-666-7788
Fax: 86-10-82849933
Email: jkinfo@jkchemical.com
Country: China
ProdList: 94838
Advantage: 76

3B Pharmachem (Wuhan) International Co.,Ltd.

Tel: 821-50328103-801 18930552037
Fax: 86-21-50328109
Email: 3bsc@sina.com
Country: China
ProdList: 15848
Advantage: 69

Chembest Research Laboratories Limited

Tel: 021-20908456
Fax: 021-58180499
Email: sales@BioChemBest.com
Country: China
ProdList: 6011
Advantage: 61

Energy Chemical

Tel: 021-021-58432009 400-005-6266
Fax: 021-58436166
Email: sales8178@energy-chemical.com
Country: China
ProdList: 44751
Advantage: 61

Nanjing Chemlin Chemical Co., Ltd

Tel: 025-83697070
Fax: +86-25-83453306
Email: info@chemlin.com.cn
Country: China
ProdList: 17988
Advantage: 64

Chemsky（shanghai）International Co.,Ltd.

Tel: 021-50135380
Email: shchemsky@sina.com
Country: China
ProdList: 32344
Advantage: 50

BOC Sciences

Tel: 1-631-485-4226; 16314854226
Email: info@bocsci.com
Country: United States
ProdList: 14059
Advantage: 65

S.Z. PhyStandard Bio-Tech. Co., Ltd.

Tel: 0755-83725681-603
Fax: +86 755 28094224
Country: China
ProdList: 4505
Advantage: 50

Beijing HuaMeiHuLiBiological Chemical

Tel: 010-56205725
Fax: 010-65763397
Email: waley188@sohu.com
Country: China
ProdList: 12338
Advantage: 58

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View Lastest Price from Alverine citrate manufacturers

Shanghai Joiny Pharmaceutical Co.,LTD

Product: Alverine citrate 5560-59-8
Price: US $0.00/kg
Min. Order: 1kg
Purity: 99.0~101.0%
Supply Ability: 2000kg
Release date: 2024-03-21

Henan Aochuang Chemical Co.,Ltd.

Product: Alverine citrate 5560-59-8
Price: US $0.00-0.00/KG
Min. Order: 1KG
Purity: 98%
Supply Ability: 1Ton
Release date: 2022-10-13

Baoji Guokang Healthchem co.,ltd

Product: Alverine citrate 5560-59-8
Price: US $396.00/KG
Min. Order: 1Kg/Bag
Purity: 99
Supply Ability: 6000kg
Release date: 2021-06-04

5560-59-8, Alverine citrateRelated Search:

Ethyl acetate Sodium citrate BISMUTH POTASSIUM CITRATE Calcium citrate Citric acid monohydrate Potassium Citrate Ethanol Ethylparaben Sildenafil citrate Alverine TAMOXIFEN CITRATE(RG) D/L-AMPHETAMINE HYDROCHLORIDE 3-METHYLGLUTARIC ACID Citric acid TRICARBALLYLIC ACID (S)-(+)-CITRAMALIC ACID 2-Hydroxyisobutyric acid (R)-(-)-CITRAMALIC ACID

Alverine base or citrate

alverine dihydrogen citrate

Profenil citrate

AntispasMin

CalMabel

n-ethyl-3,3'-diphenyldipropylamine citrate

N-ETHYL-3,3'-DIPHENYLDIPROPYLAMINE CITRATE SALT

N-ETHYL-3,3-DIPHENYLDIPROPYLAMINE CITRATE SALT

GaMatran

N-Ethyl-N-(3-phenylpropyl)benzenepropanaMine 2-Hydroxy-1,2,3- propanetricarboxylate

NSC 35459

Profenine

Prophelan

Proverine

Spacolin

SpasMaverine

SpasMona

Alverine citrate iMpurity

Benzenepropanamine, N-ethyl-N-(3-phenylpropyl)-, 2-hydroxy-1,2,3-propanetricarboxylate (1:1)

N-Ethyl-3-phenyl-N-(3-phenylpropyl)propan-1-amine citrate

Alverine Citric Acid

Alverine Citrate Imp. (EP)

BIS-GAMMA-PHENYLPROPYLETHYLAMINE DIHYDROGEN CITRATE

ALVERINE CITRATE

ALVERINE CITRATE SALT

Alverine Citric Acid-D5

Alverine citrate CRS

Alverine citrate ISO 9001：2015 REACH

Alverine Citrate (NSC 35459)

Alverine citrate EP9.0

N-Ethyl-3-phenyl-N-(3-phenylpropyl)propan-1-amine 2-hydroxypropane-1,2,3-tricarboxylate

5560-59-8

C26H35NO7

C20H27NC6H8O7

Organic Building Blocks

Nitrogen Compounds

Building Blocks

Amine Salts

Pharmaceutical intermediates

SPASMAVERINE

Amines

Aromatics

Intermediates & Fine Chemicals

Pharmaceuticals