2-Hydroxyisobutyric acid

Product Name: 2-Hydroxyisobutyric acid
CAS No.: 594-61-6
Chemical Name: 2-Hydroxyisobutyric acid
Synonyms: 2-HYDROXY-2-METHYLPROPANOIC ACID;2-hydroxyisobutyrate;ALPHA-HYDROXYISOBUTYRIC ACID;α-Hydroxyisobutyric acid;|á-Hydroxyisobutyric acid;2-HYDROXY-2-METHYLPROPIONIC ACID;Propanoic acid, 2-hydroxy-2-methyl-;(CH3)2COHCOOH;METHYL LACTIC ACID;RARECHEM AL BO 0199
CBNumber: CB0379920
Molecular Formula: C4H8O3
Formula Weight: 104.1
MOL File: 594-61-6.mol

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2-Hydroxyisobutyric acid Property

Melting point:: 76-80 °C(lit.)
Boiling point:: 84 °C1.5 mm Hg(lit.)
Density: 11412
refractive index: 1.4761 (estimate)
Flash point:: 114°C/12mm
storage temp.: Sealed in dry,Room Temperature
solubility: water: soluble10%, clear to very slightly hazy, colorless
pka: pK1:3.717 (25°C,μ=0.1)
form: Solid
color: White to Off-White
Water Solubility: Soluble in water, ether, alcohol, methanol and hot benzene.
BRN: 1744739
Cosmetics Ingredients Functions: FRAGRANCE
InChI: 1S/C4H8O3/c1-4(2,7)3(5)6/h7H,1-2H3,(H,5,6)
InChIKey: BWLBGMIXKSTLSX-UHFFFAOYSA-N
SMILES: CC(C)(O)C(O)=O
LogP: -0.360
CAS DataBase Reference: 594-61-6(CAS DataBase Reference)
NIST Chemistry Reference: Propanoic acid, 2-hydroxy-2-methyl-(594-61-6)
EPA Substance Registry System: Propanoic acid, 2-hydroxy-2-methyl- (594-61-6)

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Safety

Hazard Codes: Xi
Risk Statements: 37/38-41-36/37/38
Safety Statements: 26-39-25-36
WGK Germany: 3
Hazard Note: Irritant
TSCA: TSCA listed
HS Code: 29181980
Storage Class: 11 - Combustible Solids
Hazard Classifications: Eye Dam. 1
Skin Irrit. 2
STOT SE 3

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H315Causes skin irritation

H318Causes serious eye damage

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P403+P233Store in a well-ventilated place. Keep container tightly closed.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 323594
Product name: α-Hydroxyisobutyric acid
Purity: 99%
Packaging: 25g
Price: $22.4
Updated: 2025/07/31

Sigma-Aldrich

Product number: 164976
Product name: α-Hydroxyisobutyric acid
Purity: 98%
Packaging: 25g
Price: $40.75
Updated: 2025/07/31

TCI Chemical

Product number: M0360
Product name: 2-Hydroxyisobutyric Acid
Purity: >98.0%(T)
Packaging: 25g
Price: $25
Updated: 2025/07/31

TCI Chemical

Product number: M0360
Product name: 2-Hydroxyisobutyric Acid
Purity: >98.0%(T)
Packaging: 100g
Price: $62
Updated: 2025/07/31

Sigma-Aldrich

Product number: 323594
Product name: α-Hydroxyisobutyric acid
Purity: 99%
Packaging: 100g
Price: $68.7
Updated: 2025/07/31

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2-Hydroxyisobutyric acid Chemical Properties,Usage,Production

Chemical Properties

white to off-white needle-like crystals or

Uses

2-Hydroxyisobutyric acid is used as an electrolyte in the separation of the metal ions by on-line cyclic voltammetry. It is also used as a building block for the synthesis of polymers. Its conjugate base, 2-hydroxybutyrate is utilized to catabolize L-threonine as well as synthesize glutathione. Further, it is used as an indicator for the early detection insulin resistance in non-diabetic subjects.

Uses

α-Hydroxyisobutyric acid was used as background electrolyte for separation and detection of the metal ions by on-line cyclic voltammetry.

Uses

2-Hydroxyisobutyric acid is used as background electrolyte for separation and detection of the metal ions by on-line cyclic voltammetry.

Definition

ChEBI: A 2-hydroxy monocarboxylic acid that is isobutyric acid bearing a hydroxy substituent at position 2. It is a metabolite of methyl tertiary-butyl ether.

Synthesis Reference(s)

The Journal of Organic Chemistry, 23, p. 1488, 1958 DOI: 10.1021/jo01104a022

General Description

α-Hydroxyisobutyric acid (2-hydroxyisobutyric acid) is the building block for polymer synthesis. It forms complexes with Eu(III) and has been studied by time resolved fluorescence spectroscopy.

2-Hydroxyisobutyric acid Preparation Products And Raw materials

Raw materials

Preparation Products

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2-Hydroxyisobutyric acid Suppliers

Americas 1 Austria 1 Belgium 1 Canada 1 China 322 Czech Republic 2 Europe 2 France 2 Germany 5 India 10 Japan 7 Slovakia 1 Switzerland 6 Ukraine 1 United Kingdom 13 United States 49 USA 1 Global 425

Wuhan Xinyangruihe Chemical Technology Co., Ltd.

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View Lastest Price from 2-Hydroxyisobutyric acid manufacturers

Shandong Vital Biotechnology Co., Ltd.

Product: 2-Hydroxyisobutyric acid 594-61-6
Price: US $0.00-0.00/kg
Min. Order: 1kg
Purity: 98%
Supply Ability: 100tons
Release date: 2025-11-19

RongNa Biotechnology Co.,Ltd

Product: 2-Hydroxyisobutyric acid 594-61-6
Price: US $10.00/ASSAYS
Min. Order: 1ASSAYS
Purity: 99%
Supply Ability: 1 ton
Release date: 2025-08-16

ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD

Product: 2-Hydroxyisobutyric acid 594-61-6
Price: US $50.00-10.00/kg
Min. Order: 1kg
Purity: 99%，Electronic grade(Single metal impurity≤ 10ppb)
Supply Ability: 100kg
Release date: 2025-07-17

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|á-Hydroxyisobutyric acid

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2-HydroxyisobutyricAcid&gt

α-Hydroxyisobutyric acid

2-hydroxyisobutyrate

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594-61-6

C4H8O3

CH32CHOHCOOH

Building Blocks

Carboxylic Acids

Carbonyl Compounds

C1 to C5

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Chemical Synthesis

Organic Building Blocks

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