2-Hydroxyisobutyric acid

Product Name: 2-Hydroxyisobutyric acid
CAS No.: 594-61-6
Chemical Name: 2-Hydroxyisobutyric acid
Synonyms: 2-HYDROXY-2-METHYLPROPANOIC ACID;2-hydroxyisobutyrate;ALPHA-HYDROXYISOBUTYRIC ACID;α-Hydroxyisobutyric acid;|á-Hydroxyisobutyric acid;2-HYDROXY-2-METHYLPROPIONIC ACID;Propanoic acid, 2-hydroxy-2-methyl-;(CH3)2COHCOOH;METHYL LACTIC ACID;RARECHEM AL BO 0199
CBNumber: CB0379920
Molecular Formula: C4H8O3
Formula Weight: 104.1
MOL File: 594-61-6.mol

More

Less

2-Hydroxyisobutyric acid Property

Melting point:: 76-80 °C(lit.)
Boiling point:: 84 °C1.5 mm Hg(lit.)
Density: 11412
refractive index: 1.4761 (estimate)
Flash point:: 114°C/12mm
storage temp.: Sealed in dry,Room Temperature
solubility: water: soluble10%, clear to very slightly hazy, colorless
pka: pK1:3.717 (25°C,μ=0.1)
form: Solid
color: White to Off-White
Water Solubility: Soluble in water, ether, alcohol, methanol and hot benzene.
BRN: 1744739
LogP: -0.360
CAS DataBase Reference: 594-61-6(CAS DataBase Reference)
NIST Chemistry Reference: Propanoic acid, 2-hydroxy-2-methyl-(594-61-6)
EPA Substance Registry System: Propanoic acid, 2-hydroxy-2-methyl- (594-61-6)

More

Less

Safety

Hazard Codes: Xi
Risk Statements: 37/38-41-36/37/38
Safety Statements: 26-39-25-36
WGK Germany: 3
Hazard Note: Irritant
TSCA: Yes
HS Code: 29181980

More

Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H315Causes skin irritation

H318Causes serious eye damage

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P403+P233Store in a well-ventilated place. Keep container tightly closed.

More

Less

N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 323594
Product name: α-Hydroxyisobutyric acid
Purity: 99%
Packaging: 25g
Price: $22.4
Updated: 2025/07/31

Sigma-Aldrich

Product number: 164976
Product name: α-Hydroxyisobutyric acid
Purity: 98%
Packaging: 25g
Price: $40.75
Updated: 2025/07/31

TCI Chemical

Product number: M0360
Product name: 2-Hydroxyisobutyric Acid
Purity: >98.0%(T)
Packaging: 25g
Price: $25
Updated: 2025/07/31

TCI Chemical

Product number: M0360
Product name: 2-Hydroxyisobutyric Acid
Purity: >98.0%(T)
Packaging: 100g
Price: $62
Updated: 2025/07/31

Sigma-Aldrich

Product number: 323594
Product name: α-Hydroxyisobutyric acid
Purity: 99%
Packaging: 100g
Price: $68.7
Updated: 2025/07/31

More

Less

2-Hydroxyisobutyric acid Chemical Properties,Usage,Production

Chemical Properties

white to off-white needle-like crystals or

Uses

2-Hydroxyisobutyric acid is used as an electrolyte in the separation of the metal ions by on-line cyclic voltammetry. It is also used as a building block for the synthesis of polymers. Its conjugate base, 2-hydroxybutyrate is utilized to catabolize L-threonine as well as synthesize glutathione. Further, it is used as an indicator for the early detection insulin resistance in non-diabetic subjects.

Uses

α-Hydroxyisobutyric acid was used as background electrolyte for separation and detection of the metal ions by on-line cyclic voltammetry.

Uses

2-Hydroxyisobutyric acid is used as background electrolyte for separation and detection of the metal ions by on-line cyclic voltammetry.

Definition

ChEBI: A 2-hydroxy monocarboxylic acid that is isobutyric acid bearing a hydroxy substituent at position 2. It is a metabolite of methyl tertiary-butyl ether.

Synthesis Reference(s)

The Journal of Organic Chemistry, 23, p. 1488, 1958 DOI: 10.1021/jo01104a022

General Description

α-Hydroxyisobutyric acid (2-hydroxyisobutyric acid) is the building block for polymer synthesis. It forms complexes with Eu(III) and has been studied by time resolved fluorescence spectroscopy.

2-Hydroxyisobutyric acid Preparation Products And Raw materials

Raw materials

Preparation Products

More

Less

2-Hydroxyisobutyric acid Suppliers

Americas 1 Austria 1 Belgium 1 Canada 1 China 322 Czech Republic 2 Europe 2 France 2 Germany 5 India 10 Japan 7 Slovakia 1 Switzerland 6 Ukraine 1 United Kingdom 13 United States 49 USA 1 Global 425

Wuhan Xinyangruihe Chemical Technology Co., Ltd.

Tel: 13720274133
Fax: 027-83850377
Email: 2395204132@qq.com
Country: China
ProdList: 1038
Advantage: 58

Hubei Bojie Biotechnology Co., Ltd

Tel: 0713-2060728 15629612610
Email: 825477621@qq.com
Country: China
ProdList: 500
Advantage: 58

SHANGHAI BANGCHENG CHEMICAL Co.,Ltd.

Tel: 021-69106960 13701823733
Fax: 021-69106780
Email: 13701823733@163.com
Country: China
ProdList: 4641
Advantage: 60

Weifang QianJin Fine Chemical Co., Ltd.

Tel: 18753684562
Fax: 0536-8897109
Email: 1577399715@qq.COM
Country: China
ProdList: 1735
Advantage: 55

Shanghai Huishen Chemical Co., Ltd

Tel: 021-021-56354726 15317631096
Email: 2936900186@qq.com
Country: China
ProdList: 46
Advantage: 58

J & K SCIENTIFIC LTD.

Tel: 18210857532; 18210857532
Fax: 86-10-82849933
Email: jkinfo@jkchemical.com
Country: China
ProdList: 96815
Advantage: 76

Meryer (Shanghai) Chemical Technology Co., Ltd.

Tel: 4006356688 18621169109
Fax: 86-21-61259102
Email: market03@meryer.com
Country: China
ProdList: 40228
Advantage: 62

3B Pharmachem (Wuhan) International Co.,Ltd.

Tel: 821-50328103-801 18930552037
Fax: 86-21-50328109
Email: 3bsc@sina.com
Country: China
ProdList: 15838
Advantage: 69

Alfa Aesar

Tel: 400-6106006
Fax: 021-67582001/03/05
Email: saleschina@alfa-asia.com
Country: China
ProdList: 30123
Advantage: 84

TAIYUAN RHF CO.,LTD.

Tel: +86 351 7031519
Fax: +86 351 7031519
Email: sales@RHFChem.com
Country: China
ProdList: 2338
Advantage: 56

More

Less

View Lastest Price from 2-Hydroxyisobutyric acid manufacturers

Shandong Vital Biotechnology Co., Ltd.

Product: 2-Hydroxyisobutyric acid 594-61-6
Price: US $0.00-0.00/kg
Min. Order: 1kg
Purity: 98%
Supply Ability: 100tons
Release date: 2025-11-19

RongNa Biotechnology Co.,Ltd

Product: 2-Hydroxyisobutyric acid 594-61-6
Price: US $10.00/ASSAYS
Min. Order: 1ASSAYS
Purity: 99%
Supply Ability: 1 ton
Release date: 2025-08-16

ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD

Product: 2-Hydroxyisobutyric acid 594-61-6
Price: US $50.00-10.00/kg
Min. Order: 1kg
Purity: 99%，Electronic grade(Single metal impurity≤ 10ppb)
Supply Ability: 100kg
Release date: 2025-07-17

594-61-6, 2-Hydroxyisobutyric acidRelated Search:

Lactic acid Ethyl 2-(Chlorosulfonyl)acetate Isobutyric acid 3-Hydroxybenzaldehyde 2-(4-Chlorophenoxy)-2-methylpropionic acid 3-(4-Hydroxyphenyl)propionic acid CHLOROPHOSPHONAZO III Folic acid Methyl (R)-(-)-3-hydroxybutyrate Hydroxy silicone oil Dimethyl 2,2'-azobis(2-methylpropionate) Sucrose acetate isobutyrate 2,2-Bis(hydroxymethyl)propionic acid L(+)-Lactic acid 2,3-Dibromopropionic acid Methyl 2-bromo-2-methylpropionate Citric acid Ascoric Acid

Propanoic acid, 2-methyl-2-hydroxy-

A-HYDROXY-ISO-BUTYRIC ACID

2-MethyllaCLic Acid

alpha-Hydroxyisobutyric acid 98%

2-Hydroxyisobutyric acid for synthesis

RARECHEM AL BO 0199

alpha-Hydroxyisobutanoic acid

Hydroxydimethylacetic acid

Hydroxyisobutyricacid

Lactic acid, 2-methyl-

Lactic acid, 2-methyl-, L-

(CH3)2COHCOOH

2-hydroxy-2-methyl-propanoicaci

ALPHA-HYDROXYISOBUTYRIC ACID

2,2-DIMETHYLGLYCOLIC ACID

2-HYDROXY-2-METHYLPROPIONIC ACID

2-HYDROXY-2-METHYLPROPANOIC ACID

2-HYDROXYISOBUTYRIC ACID

2-METHYLLACTIC ACID

METHYL LACTIC ACID

2-Hydroxy-#niso-butyric acid

2 2-Hydroxyisobutyric Acid

Propanoic acid, 2-hydroxy-2-methyl-

2,4-dichlorodibenzoyl peroxide

2-hydroxy-2-methylpropanoate

2-HYDROXYISOBUTYRIC ACID (2-HYDROXY-2-METHYLPROPIONIC ACID)

2-Hydroxyisobutyricacid,99%

PROPANOICACID,2-HYDROXY-2-

Hydroxy-2-methylpropanoic acid, 2-: (2-Methyllactic acid)

2-Hydroxy-2-methylpropionic acid, 2-Methyllactic acid

2-Hydroxyisobutyric acid,98%

α-Hydroxyisobutyric acid,2-Hydroxy-2-methylpropionic acid, 2-Methyllactic acid

2-Hydroxyisobutanoic acid

2-Hydroxyisobutyric acid, 99% (dry wt.), water <2%

2-Hydroxyisobutyric

|á-Hydroxyisobutyric acid

2-Hydroxyisobutyric acid, 98% 25GR

2-HydroxyisobutyricAcid&gt

α-Hydroxyisobutyric acid

2-hydroxyisobutyrate

2-hydroxyisobutyricaci

2-methyl-2-hydroxypropanoic acid

2-Hydroxyisobutyric Acid, ≥ 98.0%

2-Methyl-2-hydroxypropionic acid

2-Hydroxyisobutyric acid - [H72872]

594-61-6

C4H8O3

CH32CHOHCOOH

Building Blocks

Carboxylic Acids

Carbonyl Compounds

C1 to C5

Organic Building Blocks

Carboxylic Acids

Chemical Synthesis

Organic Building Blocks

FINE Chemical & INTERMEDIATES

Organic acids