2-AMINO-5-BROMOPHENOL
Uses- Product Name
- 2-AMINO-5-BROMOPHENOL
- CAS No.
- 38191-34-3
- Chemical Name
- 2-AMINO-5-BROMOPHENOL
- Synonyms
- 2-AMino-5-broMphenol;2-AMINO-5-BROMOPHENOL;Phenol,2-amino-5-bromo-;4-Bromo-2-hydroxyaniline;2-Amino-5-bromophenol 99%;4-Bromo-2-hydroxylaniline;4-Bromo-2-hydroxylbenzenamine
- CBNumber
- CB3121649
- Molecular Formula
- C6H6BrNO
- Formula Weight
- 188.02
- MOL File
- 38191-34-3.mol
2-AMINO-5-BROMOPHENOL Property
- Melting point:
- 146-147 °C
- Boiling point:
- 265.0±25.0 °C(Predicted)
- Density
- 1.768±0.06 g/cm3(Predicted)
- storage temp.
- under inert gas (nitrogen or Argon) at 2–8 °C
- form
- powder
- pka
- 8.79±0.10(Predicted)
- color
- brown
- InChI
- InChI=1S/C6H6BrNO/c7-4-1-2-5(8)6(9)3-4/h1-3,9H,8H2
- InChIKey
- DRQWUAAWZFIVTF-UHFFFAOYSA-N
- SMILES
- C1(O)=CC(Br)=CC=C1N
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H332Harmful if inhaled
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- A602058
- Product name
- 2-Amino-5-bromophenol
- Packaging
- 100mg
- Price
- $45
- Updated
- 2021/12/16
- Product number
- A602058
- Product name
- 2-Amino-5-bromophenol
- Packaging
- 500mg
- Price
- $65
- Updated
- 2021/12/16
- Product number
- J98859
- Product name
- 2-Amino-5-bromophenol
- Packaging
- 1g
- Price
- $14
- Updated
- 2021/12/16
- Product number
- 074218
- Product name
- 2-Amino-5-bromophenol
- Purity
- 95+%
- Packaging
- 1g
- Price
- $24
- Updated
- 2021/12/16
- Product number
- 4656-9-X0
- Product name
- 2-Amino-5-bromophenol
- Purity
- 98%
- Packaging
- 1g
- Price
- $29
- Updated
- 2021/12/16
2-AMINO-5-BROMOPHENOL Chemical Properties,Usage,Production
Uses
2-Amino-5-bromophenol is used as an intermediate in organic synthesis and pharmaceuticals.
Chemical Properties
white to light yellow solid
Synthesis
27684-84-0
38191-34-3
General procedure for the synthesis of 2-amino-5-bromophenol from 5-bromo-2-nitrophenol: 5-bromo-2-nitrophenol (0.292 g, 1.34 mmol) was dissolved in 0.5% aqueous sodium hydroxide solution (30 mL) and stirred until completely dissolved. Sodium bisulfite (2.00 g, 85% pure, 9.76 mmol) was added to the reaction system and the reaction was stirred at room temperature for 15 minutes. After completion of the reaction, the reaction mixture was slowly acidified with dilute hydrochloric acid to pH 5. Subsequently, the reaction mixture was extracted with diethyl ether (40 mL) in three portions, the organic phases were combined and dried over anhydrous sodium sulfate. The organic phase was concentrated under reduced pressure to give the crude product 2-amino-5-bromophenol (0.533 g, melting point 99.5-100.5 °C). The crude product was recrystallized by mixed solvent recrystallization from ether/hexane to give the pure product 2-amino-5-bromophenol (0.151 g, 0.80 mmol, 60% yield; melting point 125-127 °C (decomposition), melting point reported in the literature as 149.5-150.5 °C (Boyland, E et al., 1954)). The structure of the product was confirmed by 1H NMR (CD3CN, 500 MHz) and IR (KBr): 1H NMR δ 7.08 (bs, 1H), 6.82 (d, 1H, J=2Hz), 6.78 (dd, 1H, J=8.2Hz), 6.56 (d, 1H, J=8Hz), 4.03 (bs, 2H); IR 3496 (wide) 3377, 3298, 1598, 1502, 1431, 1269, 1210, 916, 877 cm-1.
References
[1] Journal of Organic Chemistry, 1990, vol. 55, # 9, p. 2736 - 2742
[2] Chemistry - A European Journal, 2011, vol. 17, # 33, p. 9076 - 9082
[3] ACS Medicinal Chemistry Letters, 2014, vol. 5, # 5, p. 592 - 597
[4] MedChemComm, 2015, vol. 6, # 7, p. 1375 - 1380
[5] Bioorganic and Medicinal Chemistry, 2005, vol. 13, # 16, p. 4960 - 4971
2-AMINO-5-BROMOPHENOL Preparation Products And Raw materials
Raw materials
Preparation Products
2-AMINO-5-BROMOPHENOL Suppliers
- Tel
- 0371-55676069 18137782046
- Fax
- 0371-55676069
- 1821614734@qq.com
- Country
- China
- ProdList
- 398
- Advantage
- 58
- Tel
- 15150528611
- Fax
- 151-5052-8611
- 779881375@qq.com
- Country
- China
- ProdList
- 66
- Advantage
- 58
- Tel
- 0717-6855399 15377615856
- sales@sndswyy.cn
- Country
- China
- ProdList
- 67
- Advantage
- 58
- Tel
- 0573-85609002 18367600069;
- zhejia01@163.com
- Country
- China
- ProdList
- 8887
- Advantage
- 58
- Tel
- 021-34979681; 17701870669
- Fax
- 021-34979681
- 41513101@qq.com
- Country
- China
- ProdList
- 1785
- Advantage
- 55
- Tel
- 86-18539896799 18539896799
- 71889632@qq.com
- Country
- China
- ProdList
- 182
- Advantage
- 58
- Tel
- 18210857532; 18210857532
- Fax
- 86-10-82849933
- jkinfo@jkchemical.com
- Country
- China
- ProdList
- 96815
- Advantage
- 76
- Tel
- 4006356688 18621169109
- Fax
- 86-21-61259102
- market03@meryer.com
- Country
- China
- ProdList
- 40228
- Advantage
- 62
- Tel
- +86 (0) 571 85 58 67 18
- Fax
- 0086-571-85864795
- Country
- China
- ProdList
- 18207
- Advantage
- 66
- Tel
- 13817811078
- Fax
- 86-021-50426522,50426273
- sales@jingyan-chemical.com
- Country
- China
- ProdList
- 9976
- Advantage
- 60
- Tel
- 0573-85285100 18627885956
- Fax
- 0573-85285100
- isenchem@163.com
- Country
- China
- ProdList
- 9309
- Advantage
- 66
- Tel
- 21-57721279
- Fax
- QQ：14057904
- sales@shydchem.com.cn
- Country
- China
- ProdList
- 998
- Advantage
- 56
- Tel
- 28-83379370 13880556291
- Fax
- 028-87747383
- tcy@tcypharm.com
- Country
- China
- ProdList
- 510
- Advantage
- 57
- Tel
- 021-50795510 4000665055
- Fax
- 021-50795055
- sales@accelachem.com
- Country
- China
- ProdList
- 11035
- Advantage
- 64
- Tel
- 021-58099652-8005 13585536065
- Fax
- 021-58099609
- bin.wu@shlschem.com
- Country
- China
- ProdList
- 9883
- Advantage
- 59
- Tel
- 021-31038972,31038973 17321035817
- Fax
- +86-21-51385350
- sales@harvest-chem.com
- Country
- China
- ProdList
- 2816
- Advantage
- 64
- Tel
- 025-83697070
- Fax
- +86-25-83453306
- info@chemlin.com.cn
- Country
- China
- ProdList
- 16077
- Advantage
- 64
- Tel
- 021-54306202 13764082696
- info@hanhongsci.com
- Country
- China
- ProdList
- 42934
- Advantage
- 64
- Tel
- 010-59484199 18611897322
- sales@eternalchem.com
- Country
- China
- ProdList
- 4383
- Advantage
- 60
- Tel
- 18270980682
- Fax
- 021 51613951
- mlcheng@sunwaypharm.cn
- Country
- China
- ProdList
- 8669
- Advantage
- 57
- Tel
- Please Send Email 18652950785
- Fax
- 025-87193546
- chemweiao@163.com
- Country
- China
- ProdList
- 4378
- Advantage
- 65
- Tel
- 021-56491756 13512199871
- Fax
- 021-5649-1756
- 2819742715@qq.com
- Country
- China
- ProdList
- 3997
- Advantage
- 55
- Tel
- 18986259541
- Fax
- 027-87840182
- sales@3stc.com
- Country
- China
- ProdList
- 3764
- Advantage
- 58
- Tel
- 022-58013646 13011382049
- Fax
- 022-23854368
- sales@jinyudachem.com
- Country
- China
- ProdList
- 1930
- Advantage
- 55
- Tel
- 027-86697669 13986148687
- Fax
- 86-027-86697669
- sales@tcaschem.com
- Country
- China
- ProdList
- 4127
- Advantage
- 55
- Tel
- 13598610367 0373-7129549
- Fax
- 0373-8369699
- 2468833170@qq.com
- Country
- China
- ProdList
- 932
- Advantage
- 58
- Tel
- 021-58170097
- info@topbiochem.com
- Country
- China
- ProdList
- 9510
- Advantage
- 58
- Tel
- +86 21 61551611
- Fax
- +86 21 50676805
- Country
- China
- ProdList
- 9891
- Advantage
- 58
- Tel
- 13524892556
- Fax
- (86) 21 51969655， QQ： 263541193
- sales-cn@potentpharm.com
- Country
- China
- ProdList
- 1011
- Advantage
- 55
- Tel
- 4009209199
- Fax
- 86-021-52271987
- sales@9dingchem.com
- Country
- China
- ProdList
- 18209
- Advantage
- 56
- Tel
- +86-512-86881668
- Fax
- +86-512-62956001
- Country
- China
- ProdList
- 100
- Advantage
- 58
- Tel
- +86 (21) 6715-7650
- Fax
- +86 (21) 6715-7651
- sheepchem@163.com
- Country
- China
- ProdList
- 994
- Advantage
- 60
- Tel
- 027-027-87342388 18086026008
- Fax
- 027-87342388
- sales@kaymke.com
- Country
- China
- ProdList
- 3731
- Advantage
- 55
- Tel
- 021-62960152
- Fax
- 021-52212593
- 934678158@qq.com
- Country
- China
- ProdList
- 9899
- Advantage
- 55
- Tel
- +86-021-50935922
- Fax
- +86-021-33847795
- Country
- China
- ProdList
- 7865
- Advantage
- 55
- Tel
- 021-61995394 18916691159
- chemicalsea@163.com
- Country
- China
- ProdList
- 1972
- Advantage
- 58
- Tel
- 0512-56316828 4008675858
- Fax
- +86-512-56316826
- sales@amateksci.com
- Country
- China
- ProdList
- 9874
- Advantage
- 55
- Tel
- 021-60549325 18616193163
- Fax
- 021-33250306
- Country
- China
- ProdList
- 4526
- Advantage
- 56
- Tel
- 010-57495520 13521095525
- zhw512@foxmail.com
- Country
- China
- ProdList
- 488
- Advantage
- 55
- Tel
- 400-164-7117 13681763483
- Fax
- +86-21-61629029
- product02@bidepharm.com
- Country
- China
- ProdList
- 39966
- Advantage
- 60
- Tel
- 86-21-51086038
- Fax
- 86-21-51861608
- Country
- China
- ProdList
- 2930
- Advantage
- 58
- Tel
- 400-008-9730,021-54359730 400-008-9730
- Fax
- 021-54353864
- info@chemxyz.com
- Country
- China
- ProdList
- 3057
- Advantage
- 60
- Tel
- 0371-0371-13526885213 15637198702
- Fax
- 0371-63709726
- hsyykjchem@163.com
- Country
- China
- ProdList
- 3852
- Advantage
- 58
- Tel
- 021-60345187 13671753212
- Fax
- 021-34702061
- lzz841106@aliyun.com
- Country
- China
- ProdList
- 10263
- Advantage
- 55
- Tel
- 02161555100
- Fax
- -
- Country
- China
- ProdList
- 820
- Advantage
- 58
- Tel
- 0571-87396432
- Fax
- 0571-87396431
- sales@jhechem.com
- Country
- China
- ProdList
- 14912
- Advantage
- 59
- Tel
- 13598610367
- Fax
- QQ:2468833170
- 2841375912@qq.com
- Country
- China
- ProdList
- 2789
- Advantage
- 52
- Tel
- 010-1234567 18521000990
- Fax
- 86-021-33275113
- sonyuanchemical@163.com
- Country
- China
- ProdList
- 6479
- Advantage
- 50
- Tel
- 025-66028182 18626450290
- yftan@aikonchem.com
- Country
- China
- ProdList
- 16679
- Advantage
- 50
- Tel
- +86 (21) 61124340
- Fax
- +86 (21) 6129-4103
- Country
- China
- ProdList
- 9756
- Advantage
- 58
View Lastest Price from 2-AMINO-5-BROMOPHENOL manufacturers
- Product
- 2-Amino-5-bromophenol 38191-34-3
- Price
- US $0.00-0.00/kg
- Min. Order
- 1kg
- Purity
- 98%
- Supply Ability
- 1Ton
- Release date
- 2022-09-27
- Product
- 2-Amino-5-bromophenol 38191-34-3
- Price
- US $1.00/kg
- Min. Order
- 1kg
- Purity
- 95%-99%
- Supply Ability
- as request
- Release date
- 2018-12-25