Uses
ChemicalBook > CAS DataBase List > 3-AMINO-4-BROMOPHENOL

3-AMINO-4-BROMOPHENOL

Uses
Product Name
3-AMINO-4-BROMOPHENOL
CAS No.
100367-37-1
Chemical Name
3-AMINO-4-BROMOPHENOL
Synonyms
3-AMINO-4-BROMOPHENO;3-AMINO-4-BROMOPHENOL;4-BroMo-3-aMinophenol;Phenol, 3-aMino-4-broMo-;3-amino-4-bromophenol, 98%min
CBNumber
CB31484529
Molecular Formula
C6H6BrNO
Formula Weight
188.02
MOL File
100367-37-1.mol
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3-AMINO-4-BROMOPHENOL Property

Boiling point:
300.1±22.0 °C(Predicted)
Density 
1.768
storage temp. 
Keep in dark place,Sealed in dry,Room Temperature
pka
9.45±0.18(Predicted)
Appearance
Off-white to light brown Solid
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Safety

HazardClass 
IRRITANT
HS Code 
2922290090
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P321Specific treatment (see … on this label).

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P362Take off contaminated clothing and wash before reuse.

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N-Bromosuccinimide Price

TRC
Product number
A602113
Product name
3-Amino-4-bromophenol
Packaging
100mg
Price
$75
Updated
2021/12/16
AK Scientific
Product number
J98819
Product name
4-Bromo-3-aminophenol
Packaging
1g
Price
$30
Updated
2021/12/16
AK Scientific
Product number
X8496
Product name
4-Bromo-3-aminophenol
Packaging
1g
Price
$41
Updated
2021/12/16
Apolloscientific
Product number
OR400395
Product name
3-Amino-4-bromophenol
Purity
98%
Packaging
1g
Price
$41
Updated
2021/12/16
SynQuest Laboratories
Product number
4656-9-35
Product name
3-Amino-4-bromophenol
Purity
98%
Packaging
1g
Price
$48
Updated
2021/12/16
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3-AMINO-4-BROMOPHENOL Chemical Properties,Usage,Production

Uses

3-Amino-4-bromophenol is a phenolic derivative that can be used as a pharmaceutical intermediate.

Synthesis

78137-76-5

100367-37-1

(3) Reduction reaction: 13.1 g of 3-nitro-4-bromophenol and 66 g of anhydrous ethanol were added to a 250 mL three-necked flask and stirred until completely dissolved. Subsequently, 1.3 g of iron oxide catalyst and 11.3 g of 80% (w/w) hydrazine hydrate solution were added. A reflux condensing unit was installed, heated to reflux and kept for 1.5 hours. Upon completion of the reaction, complete consumption of the feedstock was confirmed by TLC monitoring, the heating was stopped and the filtration was carried out after cooling to room temperature. The filtrate was concentrated to dryness under reduced pressure, 16 mL of deionized water was added to the residue, and the pH was slowly adjusted with 10% hydrochloric acid solution under stirring to 7. At this point, a solid precipitated, and the crude product was collected by filtration, with a wet weight of about 15 g. The crude product was purified by recrystallization: the crude product was dissolved in 17 g of ethanol preheated to 60 °C until just soluble, followed by the addition of 17 g of deionized water, and stirring for 10 min. After standing at room temperature for 30 min, it was transferred to an ice water bath and continued cooling for 30 min to promote crystallization. The crystals were collected by filtration to give 8.0 g of light pink needle-like crystals (3-amino-4-bromophenol), which were analyzed by HPLC for 99% purity and 70.9% yield.

References

[1] Patent: CN102060717, 2017, B. Location in patent: Paragraph 0007; 0019; 0020

3-AMINO-4-BROMOPHENOL Preparation Products And Raw materials

Raw materials

Preparation Products

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3-AMINO-4-BROMOPHENOL Suppliers

Meryer (Shanghai) Chemical Technology Co., Ltd.
Tel
4006356688 18621169109
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86-21-61259102
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market03@meryer.com
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China
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40228
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62
JinYan Chemicals(ShangHai) Co.,Ltd.
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13817811078
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86-021-50426522,50426273
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sales@jingyan-chemical.com
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China
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9976
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Adamas Reagent, Ltd.
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400-6009262 16621234537
Fax
021-64823266
Email
chenyj@titansci.com
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China
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14101
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Shanghai Hanhong Scientific Co.,Ltd.
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021-54306202 13764082696
Email
info@hanhongsci.com
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China
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42934
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XiaoGan ShenYuan ChemPharm co,ltd
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15527768836
Email
1791901229@qq.com
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China
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6950
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PSN Pharmaceutical Technology Co., Ltd.
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86-25-57062118
Fax
86-25-57065896
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sales@jspsn.com
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China
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NovoChemy Ltd.
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021-31261262/ 49 (0)17662837245
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(0)21-33250524
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sales@novochemy.com
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Germany
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Shanghai Topbiochem Technology Co., Ltd
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021-58170097
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info@topbiochem.com
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China
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Shanghai T&W Pharmaceutical Co., Ltd.
Tel
+86 21 61551611
Fax
+86 21 50676805
Country
China
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9891
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58
Jiangsu Aikon Biopharmaceutical R&D co.,Ltd.
Tel
025-66113011 17798518460
Fax
(1)02557626880
Email
cfzhang@aikonchem.com
Country
China
ProdList
19913
Advantage
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View Lastest Price from 3-AMINO-4-BROMOPHENOL manufacturers

Hebei Chuanghai Biotechnology Co,.LTD
Product
3-AMINO-4-BROMOPHENOL 100367-37-1
Price
US $9.00/KG
Min. Order
1KG
Purity
99.9
Supply Ability
1 ton
Release date
2024-08-21
Career Henan Chemical Co
Product
3-Amino-4-bromophenol 100367-37-1
Price
US $1.00/KG
Min. Order
1KG
Purity
98%
Supply Ability
100KG
Release date
2018-12-25