ChemicalBook > CAS DataBase List > 1-O-HEXADECYL-2-O-ETHYL-SN-GLYCERO-3-PHOSPHORYLCHOLINE

1-O-HEXADECYL-2-O-ETHYL-SN-GLYCERO-3-PHOSPHORYLCHOLINE

Product Name
1-O-HEXADECYL-2-O-ETHYL-SN-GLYCERO-3-PHOSPHORYLCHOLINE
CAS No.
78858-42-1
Chemical Name
1-O-HEXADECYL-2-O-ETHYL-SN-GLYCERO-3-PHOSPHORYLCHOLINE
Synonyms
E-PAF;2-O-ETHYL-PAF;2-O-ETHYL PAF C-16;LPHUUVMLQFHHQG-AREMUKBSSA-N;1-O-HEXADECYL-2-O-ETHYL-SN-GLYCERO-3-PHOSPHORYLCHOLINE;1-O-HEXADECYL-2-O-ETHYL-SN-GLYCERYL-3-PHOSPHORYLCHOLINE
CBNumber
CB3122934
Molecular Formula
C26H56NO6P
Formula Weight
509.7
MOL File
78858-42-1.mol
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1-O-HEXADECYL-2-O-ETHYL-SN-GLYCERO-3-PHOSPHORYLCHOLINE Property

solubility 
DMF: >125 μg/ml; DMSO: <20 μg/ml; Ethanol: >10 mg/ml; PBS pH 7.2: >11 mg/ml
form 
A lyophilized powder
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P312Call a POISON CENTER or doctor/physician if you feel unwell.

P321Specific treatment (see … on this label).

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P337+P313IF eye irritation persists: Get medical advice/attention.

P403+P233Store in a well-ventilated place. Keep container tightly closed.

P405Store locked up.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Cayman Chemical
Product number
60925
Product name
2-O-ethyl PAF C-16
Purity
≥98%
Packaging
5mg
Price
$70
Updated
2024/03/01
Cayman Chemical
Product number
60925
Product name
2-O-ethyl PAF C-16
Purity
≥98%
Packaging
10mg
Price
$120
Updated
2024/03/01
Cayman Chemical
Product number
60925
Product name
2-O-ethyl PAF C-16
Purity
≥98%
Packaging
1mg
Price
$36
Updated
2024/03/01
Cayman Chemical
Product number
60925
Product name
2-O-ethyl PAF C-16
Purity
≥98%
Packaging
25mg
Price
$257
Updated
2024/03/01
American Custom Chemicals Corporation
Product number
BAR0000940
Product name
2-O-ETHYL PAF C-16
Purity
95.00%
Packaging
5MG
Price
$667.02
Updated
2021/12/16
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1-O-HEXADECYL-2-O-ETHYL-SN-GLYCERO-3-PHOSPHORYLCHOLINE Chemical Properties,Usage,Production

Description

2-O-ethyl PAF C-16 is a synthetic PAF analog which contains an ethyl group, attached by an ether linkage, at the sn-2 position. It is a less potent agonist than methylcarbamyl PAF C-16 in the induction of platelet aggregation in both human and rabbit PRP. 2-O-ethyl PAF C-16 causes aggregation of neutrophils in the presence of divalent cations and a desensitization to aggregation in the absence of divalent cations.

Uses

2-O-Ethyl PAF C-16 is a homolog of PAF and a competitive ligand for PAF receptor (Platelet-activating Factor Receptor (PAFR)). 2-O-Ethyl PAF C-16 inhibits the binding of the PAF antagonist WEB 2086 (HY-108634) to the PAF receptor with an IC50 of 21 nM[1].

Definition

ChEBI: 2-O-ethyl PAF C-16 is a glycerophosphocholine and an ether lipid.

References

[1] Aoki Y, et al. A radioreceptor binding assay for platelet-activating factor (PAF) using membranes from CHO cells expressing human PAF receptor. J Immunol Methods. 1995 Oct 26;186(2):225-31. DOI:10.1016/0022-1759(95)00147-3

1-O-HEXADECYL-2-O-ETHYL-SN-GLYCERO-3-PHOSPHORYLCHOLINE Preparation Products And Raw materials

Raw materials

Preparation Products

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1-O-HEXADECYL-2-O-ETHYL-SN-GLYCERO-3-PHOSPHORYLCHOLINE Suppliers

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78858-42-1, 1-O-HEXADECYL-2-O-ETHYL-SN-GLYCERO-3-PHOSPHORYLCHOLINERelated Search:

1,2-DIPALMITOYL-SN-GLYCERO-3-PHOSPHOCHOLINE 1-OCTADECANOYL-2-[(CIS,CIS,CIS,CIS)-5,8,11,14-EICOSATETRAENOYL]-SN-GLYCERO-3-PHOSPHOCHOLINE 1,2-DIEICOSANOYL-SN-GLYCERO-3-PHOSPHOCHOLINE 1,2-DIHEXADECYL-SN-GLYCERO-3-PHOSPHOCHOLINE DIHYDRATE 1,2-Distearoyl-sn-glycero-3-phosphocholine 1,2-DIHEPTADECANOYL-SN-GLYCERO-3-PHOSPHATIDYLCHOLINE phosphorylcholine 1-Palmitoyl-2-oleoyl-sn-glycerol-3-phosphocholine 1-OCTADECANOYL-2-[CIS-9-OCTADECENOYL]-SN-GLYCERO-3-PHOSPHOCHOLINE 1-O-HEXADECYL-2-ARACHIDONYL-SN-GLYCERO-3-PHOSPHOCHOLINE 1,2-DIDOCOSANOYL-SN-GLYCERO-3-PHOSPHOCHOLINE 1-O-HEXADECYL-2-ACETYL-SN-GLYCERO-3-PHOSPHOCHOLINE PAF (C18) 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE 1-O-HEXADECYL-(7,7,8,8-D4)-2-O-ACETYL-SN-GLYCERYL-3-PHOSPHORYLCHOLINE 1-PALMITOYL-2-PYRENEDECANOYLPHOSPHATIDYLCHOLINE POPC 1,2-DIPALMITOYL-SN-GLYCERO-3-PHOSPHO-CHO LINE MONOHYDRATE

  • 1-O-HEXADECYL-2-O-ETHYL-SN-GLYCERO-3-PHOSPHORYLCHOLINE
  • 1-O-HEXADECYL-2-O-ETHYL-SN-GLYCERYL-3-PHOSPHORYLCHOLINE
  • 2-O-ETHYL-PAF
  • 2-O-ETHYL PAF C-16
  • E-PAF
  • LPHUUVMLQFHHQG-AREMUKBSSA-N
  • 78858-42-1