Yangambin

ChemicalBook > CAS DataBase List > Yangambin

Product Name: Yangambin
CAS No.: 13060-14-5
Chemical Name: Yangambin
Synonyms: C10894;YANGAMBIN;(+)-Yangabin;Yangambin, 10 mM in DMSO;Lrioresinol B dimethyl ether;Lirioresinol B dimethyl ether;(+)-O,O-Dimethyl lirioresinol B;yangambin/Lrioresinol B dimethyl ether;inhibit,Calcium Channel,Yangambin,Ca channels,Ca2+ channels,Inhibitor;(1β,5β)-2β,6β-Bis(3,4,5-trimethoxyphenyl)-3,7-dioxabicyclo[3.3.0]octane
CBNumber: CB31246402
Molecular Formula: C24H30O8
Formula Weight: 446.49
MOL File: 13060-14-5.mol

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Yangambin Property

Melting point:: 105-106 °C
Boiling point:: 556.1±50.0 °C(Predicted)
Density: 1.183±0.06 g/cm3(Predicted)
storage temp.: Store at -20°C
solubility: Soluble in DMSO
form: Solid
color: White to off-white

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

ChemScene

Product number: CS-0032586
Product name: Yangambin
Packaging: 5mg
Price: $880
Updated: 2021/12/16

ChemScene

Product number: CS-0032586
Product name: Yangambin
Packaging: 10mg
Price: $1500
Updated: 2021/12/16

Arctom

Product number: CFN96416
Product name: Yangambin
Purity: ≥98%
Packaging: 5mg
Price: $398
Updated: 2021/12/16

Crysdot

Product number: CD32002589
Product name: Yangambin
Purity: 95+%
Packaging: 5mg
Price: $723
Updated: 2021/12/16

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Yangambin Chemical Properties,Usage,Production

Uses

Yangambin is one of the active ingredients of Radix Stellerae Chamaejasmes, which is bitter in nature and taste, and is highly toxic. It has the effects of severe diarrhea, prevent decay, and swelling. It is clinically used for erysipelas, mammary carbuncle, swollen mumps (mumps), yellow water sores, and acne.

Definition

ChEBI: Yangambin is a lignan.

Biological Activity

Yangambin is a furofuran lignan that has been isolated from plants such as the Annonaceae family, including: R. pickeli, R. exalbida and R. mucosa and Magnolia biondii. Yangambin is a selective PAF receptor antagonist that inhibits Ca2+ influx by modulating Ca2+ channels, resulting in a decrease in [Ca2+] in vascular smooth muscle cells and subsequent peripheral vasodilation. Yangambin exhibits anti-allergic activity against β-hexosaminidase with IC50 of 33.8 μM and anti-inflammatory activity with IC50 of 37.4 μM.

Yangambin Preparation Products And Raw materials

Raw materials

Preparation Products

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13060-14-5, YangambinRelated Search:

Bromothymol Blue CPNQ Hydroxytyrosol Acetate Ellagic acid Chebulinic acid 10-Gingerol 3,4-Dimethoxybenzyl alcohol Chebulic Acid Hydroxytyrosol chebulagic acid (4E,6E)-1,7-Diphenyl-4,6-heptadien-3-one 3,4-Dimethoxybenzoic acid 2-AMINO-1-BUTANOL Butyl stearate 1b Boron PHENOL-FORMALDEHYDE RESIN

Lrioresinol B dimethyl ether

(1S,3aR,4S,6aR)-Tetrahydro-1,4-bis(3,4,5-trimethoxyphenyl)-1H,3H-furo[3,4-c]furan

(+)-Yangabin

C10894

YANGAMBIN

(+)-O,O-Dimethyl lirioresinol B

(1S)-1β,4β-Bis(3,4,5-trimethoxyphenyl)-3aβ,4,6,6aβ-tetrahydro-1H,3H-furo[3,4-c]furan

(1β,5β)-2β,6β-Bis(3,4,5-trimethoxyphenyl)-3,7-dioxabicyclo[3.3.0]octane

[1S,(+)]-3aβ,4,6,6aβ-Tetrahydro-1β,4β-bis(3,4,5-trimethoxyphenyl)-1H,3H-furo[3,4-c]furan

Lirioresinol B dimethyl ether

1H,3H-Furo[3,4-c]furan, tetrahydro-1,4-bis(3,4,5-trimethoxyphenyl)-, (1S,3aR,4S,6aR)-

yangambin/Lrioresinol B dimethyl ether

(3S,3aR,6S,6aR)-3,6-bis(3,4,5-trimethoxyphenyl)-1,3,3a,4,6,6a-hexahydrofuro[3,4-c]furan

inhibit,Calcium Channel,Yangambin,Ca channels,Ca2+ channels,Inhibitor

Yangambin, 10 mM in DMSO

13060-14-5

13060-54-5