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HEXAMETHONIUM CHLORIDE

Product Name
HEXAMETHONIUM CHLORIDE
CAS No.
60-25-3
Chemical Name
HEXAMETHONIUM CHLORIDE
Synonyms
depressin;hexonchloride;hiohexchloride;hexonechloride;esomidchloride;methiumchloride;chloor-hexaviet;bistriumchloride;hestriumchloride;hexametonchloride
CBNumber
CB3125713
Molecular Formula
C12H30Cl2N2
Formula Weight
273.29
MOL File
60-25-3.mol
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HEXAMETHONIUM CHLORIDE Property

Melting point:
292°C(dec.)(lit.)
Boiling point:
423.36°C (rough estimate)
Density 
1.0558 (rough estimate)
refractive index 
1.6400 (estimate)
solubility 
H2O: soluble
form 
solid (hygroscopic)
color 
white
Water Solubility 
almost transparency
BRN 
3714806
CAS DataBase Reference
60-25-3
EPA Substance Registry System
1,6-Hexanediaminium, N,N,N,N',N',N'-hexamethyl-, dichloride (60-25-3)
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Safety

WGK Germany 
3
RTECS 
BQ8650000
HS Code 
2923.90.0100
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
H2138
Product name
Hexamethonium chloride
Purity
solid (hygroscopic)
Packaging
5g
Price
$33.9
Updated
2024/03/01
Sigma-Aldrich
Product number
H2138
Product name
Hexamethonium chloride
Purity
solid (hygroscopic)
Packaging
25g
Price
$84
Updated
2024/03/01
TCI Chemical
Product number
H0090
Product name
Hexamethonium Chloride Dihydrate
Purity
>99.0%(T)
Packaging
25g
Price
$99
Updated
2023/01/07
TCI Chemical
Product number
H0090
Product name
Hexamethonium Chloride Dihydrate
Purity
>99.0%(T)
Packaging
100g
Price
$249
Updated
2023/01/07
TCI Chemical
Product number
H0090
Product name
Hexamethonium Chloride Dihydrate
Purity
>99.0%(T)
Packaging
500g
Price
$754
Updated
2023/01/07
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HEXAMETHONIUM CHLORIDE Chemical Properties,Usage,Production

Chemical Properties

White, crystalline, hygroscopic powder; faint odor. Very soluble in water; soluble in alcohol, methanol, and n-propanol; insoluble in chloroform and ether. Available commercially as unhydrated form or as dihydrate.

Uses

Hexamethonium Chloride is a ganglionic nicotinic receptor blocker.

Uses

Hexamethonium chloride has been used to block the responses of nicotinic receptors towards it agonists. It has also been used to study the mechanosensitivity of viscerofugal neurons.

Uses

Medicine (antihypertensive).

General Description

Nicotinic acetylcholine receptor (nAChR) forms a ligand-gated ion channel made up of four different subunits. Each subunit contains an extracellular amino-terminal domain (hydrophilic) and carboxylic terminal domain and four transmembrane domains. nAChR is an allosteric and transmembrane protein localized to the neuromuscular junction.

Biochem/physiol Actions

Hexamethonium chloride preferentially blocks nicotinic receptors at autonomic ganglia, crosses blood-brain barrier only at high doses. Nicotinic acetylcholine receptor (nAChR) is responsible for cognitive functions. Blocking this receptor results in cognitive impairment. nAChR antagonist is used to study the effect of loss of receptor function. Hexamethonium has a peripheral action over blocking the nAChR.

HEXAMETHONIUM CHLORIDE Preparation Products And Raw materials

Raw materials

Preparation Products

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HEXAMETHONIUM CHLORIDE Suppliers

J & K SCIENTIFIC LTD.
Tel
010-82848833 400-666-7788
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
94837
Advantage
76
Meryer (Shanghai) Chemical Technology Co., Ltd.
Tel
021-61259108 18621169109
Fax
86-21-61259102
Email
market03@meryer.com
Country
China
ProdList
40240
Advantage
62
3B Pharmachem (Wuhan) International Co.,Ltd.
Tel
821-50328103-801 18930552037
Fax
86-21-50328109
Email
3bsc@sina.com
Country
China
ProdList
15848
Advantage
69
TCI (Shanghai) Development Co., Ltd.
Tel
021-67121386
Fax
021-67121385
Email
Sales-CN@TCIchemicals.com
Country
China
ProdList
24539
Advantage
81
Energy Chemical
Tel
021-021-58432009 400-005-6266
Fax
021-58436166
Email
sales8178@energy-chemical.com
Country
China
ProdList
44700
Advantage
61
Syntechem Co.,Ltd
Tel
Fax
E-Mail Inquiry
Email
info@syntechem.com
Country
China
ProdList
12990
Advantage
57
Maya High Purity Chemicals
Tel
+86 (573) 82222445 (0)18006601000 452520369
Fax
+86 (573) 82222643
Email
sales@maya-r.com
Country
China
ProdList
11714
Advantage
57
Spectrum Chemical Manufacturing Corp.
Tel
021-021-021-67601398-809-809-809 15221380277
Fax
021-57711696
Email
marketing_china@spectrumchemical.com
Country
China
ProdList
9664
Advantage
60
TOKYO CHEMICAL INDUSTRY CO., LTD.
Tel
03-36680489
Fax
03-3668-0520
Email
Sales-JP@TCIchemicals.com
Country
Japan
ProdList
28398
Advantage
80
TCI Europe
Tel
320-37350700
Fax
+32 (0)37350701
Email
sales@tcieurope.eu
Country
Europe
ProdList
23680
Advantage
75
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View Lastest Price from HEXAMETHONIUM CHLORIDE manufacturers

Hebei Duling International Trade Co. LTD
Product
HEXAMETHONIUM CHLORIDE 60-25-3
Price
US $9.90/kg
Min. Order
1kg
Purity
99%
Supply Ability
5000 tons
Release date
2023-01-15
WUHAN FORTUNA CHEMICAL CO., LTD
Product
Hexamethonium chloride 60-25-3
Price
US $0.00/KG
Min. Order
1KG
Purity
98%min
Supply Ability
30tons/month
Release date
2023-01-17
Henan Aochuang Chemical Co.,Ltd.
Product
HEXAMETHONIUM CHLORIDE 60-25-3
Price
US $0.00-0.00/kg
Min. Order
1kg
Purity
98%
Supply Ability
1Ton
Release date
2022-10-10

60-25-3, HEXAMETHONIUM CHLORIDERelated Search:


  • 6-hexanediaminium,n,n,n,n’,n’,n’-hexamethyl-dichloride
  • hexonchloride
  • hexonechloride
  • hiohexchloride
  • methiumchloride
  • A,W-BIS(TRIMETHYLAMMONIUM)HEXANE DICHLORIDE
  • HEXAMETHYLENEBIS[TRIMETHYLAMMONIUM CHLORIDE]
  • HEXAMETHONIUM CHLORIDE
  • HEXAMETHONIUM DICHLORIDE
  • HEXANE-1,6-BIS[TRIMETHYLAMMONIUM CHLORIDE]
  • ALPHA OMEGA-BIS(TRIMETHYLAMMONIUM)HEXANE DICHLORIDE
  • n,n,n,n',n',n'-hexamethyl-1,6-hexanediammonium dichloride
  • bistriumchloride
  • chloor-hexaviet
  • depressin
  • esomidchloride
  • hestriumchloride
  • hexamethioniumchloride
  • hexamethylenebis(trimethyl-ammoniudichloride
  • hexametonchloride
  • Hexamethonium dichloride, N,N,N,Nμ,Nμ,Nμ-Hexamethyl-1,6-hexanediaminium dichloride, N,N,N,Nμ,Nμ,Nμ-Hexamethylhexamethylenediammonium dichloride
  • Hexamethylenebis(trimethylaminium)·dichloride
  • N,N,N,N',N',N'-Hexamethyl-1,6-hexanediaminium dichloride
  • N,N,N,N',N',N'-Hexamethylhexamethylenediammonium dichloride
  • Hexamethylenebis(trimethylammonium Chloride) N,N,N,N',N',N'-Hexamethyl-1,6-hexanediammonium Dichloride Hexane-1,6-bis(trimethylammonium Chloride)
  • HexaMethoniuM Chloride&nbsp
  • N1,N1,N1,N6,N6,N6-hexaMethylhexane-1,6-diaMiniuM chloride
  • 1,6-Hexanediaminium, N1,N1,N1,N6,N6,N6-hexamethyl-, chloride (1:2)
  • HexamethoniumChlorideDihydrate&gt
  • Trimethyl-[6-(trimethylazaniumyl)hexyl]azanium Dichloride
  • Hexamethonium Chloride hydrate
  • 60-25-3
  • CH33NClCH26NClCH33
  • C12H30Cl2N2
  • C12H30Cl2N22H2O
  • Ammonium Chlorides (Quaternary)
  • Quaternary Ammonium Compounds