HEXAMETHONIUM CHLORIDE
- Product Name
- HEXAMETHONIUM CHLORIDE
- CAS No.
- 60-25-3
- Chemical Name
- HEXAMETHONIUM CHLORIDE
- Synonyms
- depressin;hexonchloride;hiohexchloride;hexonechloride;esomidchloride;methiumchloride;chloor-hexaviet;bistriumchloride;hestriumchloride;hexametonchloride
- CBNumber
- CB3125713
- Molecular Formula
- C12H30Cl2N2
- Formula Weight
- 273.29
- MOL File
- 60-25-3.mol
HEXAMETHONIUM CHLORIDE Property
- Melting point:
- 292°C(dec.)(lit.)
- Boiling point:
- 423.36°C (rough estimate)
- Density
- 1.0558 (rough estimate)
- refractive index
- 1.6400 (estimate)
- solubility
- H2O: soluble
- form
- solid (hygroscopic)
- color
- white
- Water Solubility
- almost transparency
- BRN
- 3714806
- CAS DataBase Reference
- 60-25-3
- EPA Substance Registry System
- 1,6-Hexanediaminium, N,N,N,N',N',N'-hexamethyl-, dichloride (60-25-3)
Safety
- WGK Germany
- 3
- RTECS
- BQ8650000
- HS Code
- 2923.90.0100
N-Bromosuccinimide Price
- Product number
- H2138
- Product name
- Hexamethonium chloride
- Purity
- solid (hygroscopic)
- Packaging
- 5g
- Price
- $33.9
- Updated
- 2024/03/01
- Product number
- H2138
- Product name
- Hexamethonium chloride
- Purity
- solid (hygroscopic)
- Packaging
- 25g
- Price
- $84
- Updated
- 2024/03/01
- Product number
- H0090
- Product name
- Hexamethonium Chloride Dihydrate
- Purity
- >99.0%(T)
- Packaging
- 25g
- Price
- $99
- Updated
- 2023/01/07
- Product number
- H0090
- Product name
- Hexamethonium Chloride Dihydrate
- Purity
- >99.0%(T)
- Packaging
- 100g
- Price
- $249
- Updated
- 2023/01/07
- Product number
- H0090
- Product name
- Hexamethonium Chloride Dihydrate
- Purity
- >99.0%(T)
- Packaging
- 500g
- Price
- $754
- Updated
- 2023/01/07
HEXAMETHONIUM CHLORIDE Chemical Properties,Usage,Production
Chemical Properties
White, crystalline, hygroscopic powder; faint odor. Very soluble in water; soluble in alcohol, methanol, and n-propanol; insoluble in chloroform and ether. Available commercially as unhydrated form or as dihydrate.
Uses
Hexamethonium Chloride is a ganglionic nicotinic receptor blocker.
Uses
Hexamethonium chloride has been used to block the responses of nicotinic receptors towards it agonists. It has also been used to study the mechanosensitivity of viscerofugal neurons.
Uses
Medicine (antihypertensive).
General Description
Nicotinic acetylcholine receptor (nAChR) forms a ligand-gated ion channel made up of four different subunits. Each subunit contains an extracellular amino-terminal domain (hydrophilic) and carboxylic terminal domain and four transmembrane domains. nAChR is an allosteric and transmembrane protein localized to the neuromuscular junction.
Biochem/physiol Actions
Hexamethonium chloride preferentially blocks nicotinic receptors at autonomic ganglia, crosses blood-brain barrier only at high doses. Nicotinic acetylcholine receptor (nAChR) is responsible for cognitive functions. Blocking this receptor results in cognitive impairment. nAChR antagonist is used to study the effect of loss of receptor function. Hexamethonium has a peripheral action over blocking the nAChR.
HEXAMETHONIUM CHLORIDE Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from HEXAMETHONIUM CHLORIDE manufacturers
- Product
- Hexamethonium chloride 60-25-3
- Price
- US $0.00/KG
- Min. Order
- 1KG
- Purity
- 98%min
- Supply Ability
- 30tons/month
- Release date
- 2023-01-17
- Product
- HEXAMETHONIUM CHLORIDE 60-25-3
- Price
- US $0.00-0.00/kg
- Min. Order
- 1kg
- Purity
- 98%
- Supply Ability
- 1Ton
- Release date
- 2022-10-10