ChemicalBook > CAS DataBase List > HEXAMETHONIUM CHLORIDE

HEXAMETHONIUM CHLORIDE

Product Name
HEXAMETHONIUM CHLORIDE
CAS No.
60-25-3
Chemical Name
HEXAMETHONIUM CHLORIDE
Synonyms
depressin;hexonchloride;hiohexchloride;hexonechloride;esomidchloride;methiumchloride;chloor-hexaviet;bistriumchloride;hestriumchloride;hexametonchloride
CBNumber
CB3125713
Molecular Formula
C12H30Cl2N2
Formula Weight
273.29
MOL File
60-25-3.mol
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HEXAMETHONIUM CHLORIDE Property

Melting point:
292°C(dec.)(lit.)
Boiling point:
423.36°C (rough estimate)
Density 
1.0558 (rough estimate)
refractive index 
1.6400 (estimate)
solubility 
H2O: soluble
form 
solid (hygroscopic)
color 
white
Water Solubility 
almost transparency
BRN 
3714806
CAS DataBase Reference
60-25-3
EPA Substance Registry System
1,6-Hexanediaminium, N,N,N,N',N',N'-hexamethyl-, dichloride (60-25-3)
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Safety

WGK Germany 
3
RTECS 
BQ8650000
HS Code 
2923.90.0100
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
H2138
Product name
Hexamethonium chloride
Purity
solid (hygroscopic)
Packaging
5g
Price
$33.9
Updated
2024/03/01
Sigma-Aldrich
Product number
H2138
Product name
Hexamethonium chloride
Purity
solid (hygroscopic)
Packaging
25g
Price
$84
Updated
2024/03/01
TCI Chemical
Product number
H0090
Product name
Hexamethonium Chloride Dihydrate
Purity
>99.0%(T)
Packaging
25g
Price
$99
Updated
2023/01/07
TCI Chemical
Product number
H0090
Product name
Hexamethonium Chloride Dihydrate
Purity
>99.0%(T)
Packaging
100g
Price
$249
Updated
2023/01/07
TCI Chemical
Product number
H0090
Product name
Hexamethonium Chloride Dihydrate
Purity
>99.0%(T)
Packaging
500g
Price
$754
Updated
2023/01/07
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HEXAMETHONIUM CHLORIDE Chemical Properties,Usage,Production

Chemical Properties

White, crystalline, hygroscopic powder; faint odor. Very soluble in water; soluble in alcohol, methanol, and n-propanol; insoluble in chloroform and ether. Available commercially as unhydrated form or as dihydrate.

Uses

Hexamethonium Chloride is a ganglionic nicotinic receptor blocker.

Uses

Hexamethonium chloride has been used to block the responses of nicotinic receptors towards it agonists. It has also been used to study the mechanosensitivity of viscerofugal neurons.

Uses

Medicine (antihypertensive).

General Description

Nicotinic acetylcholine receptor (nAChR) forms a ligand-gated ion channel made up of four different subunits. Each subunit contains an extracellular amino-terminal domain (hydrophilic) and carboxylic terminal domain and four transmembrane domains. nAChR is an allosteric and transmembrane protein localized to the neuromuscular junction.

Biochem/physiol Actions

Hexamethonium chloride preferentially blocks nicotinic receptors at autonomic ganglia, crosses blood-brain barrier only at high doses. Nicotinic acetylcholine receptor (nAChR) is responsible for cognitive functions. Blocking this receptor results in cognitive impairment. nAChR antagonist is used to study the effect of loss of receptor function. Hexamethonium has a peripheral action over blocking the nAChR.

HEXAMETHONIUM CHLORIDE Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from HEXAMETHONIUM CHLORIDE manufacturers

WUHAN FORTUNA CHEMICAL CO., LTD
Product
Hexamethonium chloride 60-25-3
Price
US $0.00/KG
Min. Order
1KG
Purity
98%min
Supply Ability
30tons/month
Release date
2023-01-17
Henan Aochuang Chemical Co.,Ltd.
Product
HEXAMETHONIUM CHLORIDE 60-25-3
Price
US $0.00-0.00/kg
Min. Order
1kg
Purity
98%
Supply Ability
1Ton
Release date
2022-10-10

60-25-3, HEXAMETHONIUM CHLORIDERelated Search:


  • 6-hexanediaminium,n,n,n,n’,n’,n’-hexamethyl-dichloride
  • hexonchloride
  • hexonechloride
  • hiohexchloride
  • methiumchloride
  • A,W-BIS(TRIMETHYLAMMONIUM)HEXANE DICHLORIDE
  • HEXAMETHYLENEBIS[TRIMETHYLAMMONIUM CHLORIDE]
  • HEXAMETHONIUM CHLORIDE
  • HEXAMETHONIUM DICHLORIDE
  • HEXANE-1,6-BIS[TRIMETHYLAMMONIUM CHLORIDE]
  • ALPHA OMEGA-BIS(TRIMETHYLAMMONIUM)HEXANE DICHLORIDE
  • n,n,n,n',n',n'-hexamethyl-1,6-hexanediammonium dichloride
  • bistriumchloride
  • chloor-hexaviet
  • depressin
  • esomidchloride
  • hestriumchloride
  • hexamethioniumchloride
  • hexamethylenebis(trimethyl-ammoniudichloride
  • hexametonchloride
  • Hexamethonium dichloride, N,N,N,Nμ,Nμ,Nμ-Hexamethyl-1,6-hexanediaminium dichloride, N,N,N,Nμ,Nμ,Nμ-Hexamethylhexamethylenediammonium dichloride
  • Hexamethylenebis(trimethylaminium)·dichloride
  • N,N,N,N',N',N'-Hexamethyl-1,6-hexanediaminium dichloride
  • N,N,N,N',N',N'-Hexamethylhexamethylenediammonium dichloride
  • Hexamethylenebis(trimethylammonium Chloride) N,N,N,N',N',N'-Hexamethyl-1,6-hexanediammonium Dichloride Hexane-1,6-bis(trimethylammonium Chloride)
  • HexaMethoniuM Chloride&nbsp
  • N1,N1,N1,N6,N6,N6-hexaMethylhexane-1,6-diaMiniuM chloride
  • 1,6-Hexanediaminium, N1,N1,N1,N6,N6,N6-hexamethyl-, chloride (1:2)
  • HexamethoniumChlorideDihydrate&gt
  • Trimethyl-[6-(trimethylazaniumyl)hexyl]azanium Dichloride
  • Hexamethonium Chloride hydrate
  • 60-25-3
  • CH33NClCH26NClCH33
  • C12H30Cl2N2
  • C12H30Cl2N22H2O
  • Ammonium Chlorides (Quaternary)
  • Quaternary Ammonium Compounds