ChemicalBook > CAS DataBase List > 2-Cyano-3-chloropyridine

2-Cyano-3-chloropyridine

Product Name
2-Cyano-3-chloropyridine
CAS No.
38180-46-0
Chemical Name
2-Cyano-3-chloropyridine
Synonyms
3-Chloropicolinonitrile;oro-2-cyanopyridine;2-Cyano-3-chloropyri;3-CHLORO-2-CYANOPYRIDINE;2-CYANO-3-CHLOROPYRIDINE;3-Chloro-2-cyanopyridine >3-Chloro-2-cyanopyridine ,95%;3-CHLOROPYRIDINE-2-CARBONITRILE;3-CHLORO-2-PYRIDINECARBONITRILE;2-Pyridinecarbonitrile, 3-chloro-
CBNumber
CB3127818
Molecular Formula
C6H3ClN2
Formula Weight
138.55
MOL File
38180-46-0.mol
More
Less

2-Cyano-3-chloropyridine Property

Melting point:
81-83°C
Boiling point:
100°C/3mmHg(lit.)
Density 
1.33±0.1 g/cm3(Predicted)
storage temp. 
Inert atmosphere,Room Temperature
solubility 
Methanol
pka
-2.60±0.10(Predicted)
form 
Solid
color 
Light Yellow
InChI
InChI=1S/C6H3ClN2/c7-5-2-1-3-9-6(5)4-8/h1-3H
InChIKey
YDPLFBIGFQFIDB-UHFFFAOYSA-N
SMILES
C1(C#N)=NC=CC=C1Cl
CAS DataBase Reference
38180-46-0(CAS DataBase Reference)
More
Less

Safety

Hazard Codes 
T,Xi
Risk Statements 
25-36/37/38-20/21/22
Safety Statements 
45-36/37-22
RIDADR 
2811
HazardClass 
6.1
HazardClass 
IRRITANT-HARMFUL
PackingGroup 
Ⅲ
HS Code 
29333990
More
Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H301Toxic if swalloed

H302Harmful if swallowed

H311Toxic in contact with skin

H315Causes skin irritation

H319Causes serious eye irritation

H332Harmful if inhaled

H335May cause respiratory irritation

Precautionary statements

P301+P310IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P309IF exposed or if you feel unwell:

P310Immediately call a POISON CENTER or doctor/physician.

More
Less

N-Bromosuccinimide Price

TCI Chemical
Product number
C3022
Product name
3-Chloro-2-cyanopyridine
Purity
>98.0%(GC)
Packaging
1g
Price
$16
Updated
2025/07/31
TCI Chemical
Product number
C3022
Product name
3-Chloro-2-cyanopyridine
Purity
>98.0%(GC)
Packaging
5g
Price
$42
Updated
2025/07/31
Usbiological
Product number
C8397-02
Product name
2-Cyano-3-chloropyridine
Packaging
250mg
Price
$425
Updated
2021/12/16
TRC
Product number
C962500
Product name
2-Cyano-3-chloropyridine
Packaging
1g
Price
$195
Updated
2021/12/16
TRC
Product number
C962500
Product name
2-Cyano-3-chloropyridine
Packaging
5g
Price
$880
Updated
2021/12/16
More
Less

2-Cyano-3-chloropyridine Chemical Properties,Usage,Production

Chemical Properties

Light Yellow Solid

Uses

2-Cyano-3-chloropyridine (cas# 38180-46-0) is a compound useful in organic synthesis.

Synthesis

7677-24-9

38180-46-0

3-Chloro-2-cyanopyridine (44A, 2.59 g, 20 mmol) was used as starting material and mixed with trimethylmethylsilyl cyanide (5.95 g, 60 mmol), triethylamine (Et3N, 4.05 g, 40 mmol), and acetonitrile (20 mL) in a 250 mL three-necked round-bottom flask. The reaction mixture was refluxed under nitrogen protection for 6 h. Complete consumption of raw materials was confirmed by HPLC analysis. Upon completion of the reaction, the cooled reaction mixture was concentrated under reduced pressure to give a brown semi-solid. The semi-solid was extracted by partitioning with 3N Na2CO3 aqueous solution and dichloromethane (CH2Cl2). The organic layer was washed sequentially with water and brine, dried over anhydrous magnesium sulfate (MgSO4), filtered and concentrated under reduced pressure. The resulting residue was purified by fast chromatography using 5% ether (Et2O)/dichloromethane (CH2Cl2) as eluent, and the target product 44B was finally obtained as a white crystalline solid (1.84 g, 67% yield). The structure of the product was confirmed by 1H NMR (CDCl3): δ 7.37 (dd, J = 4.7, 8.4 Hz, 1H), 7.73 (dd, J = 1.4, 8.2 Hz, 1H), 8.47 (dd, J = 1.3, 4.6 Hz, 1H); LC/MS analysis showed m/z 139 [M + H]+.

References

[1] Patent: US2004/19063, 2004, A1
[2] Patent: US2004/181064, 2004, A1

2-Cyano-3-chloropyridine Preparation Products And Raw materials

Raw materials

Trimethylsilyl cyanide Acetonitrile Hydrogen peroxide 3-Chloropyridine Potassium carbonate Triethylamine Acetic acid

Preparation Products

More
Less

2-Cyano-3-chloropyridine Suppliers

Americas 1 Canada 2 China 217 Europe 1 France 2 Germany 8 India 10 Japan 1 Switzerland 1 The Netherlands 1 United Kingdom 12 United States 36 Global 292
Jinan LuoHe PharmaTech Co., Ltd.
Tel
86-0531-68658065 15726150375
Fax
0531-68658065
Email
1071018499@qq.com
Country
China
ProdList
525
Advantage
58
J & K SCIENTIFIC LTD.
Tel
18210857532; 18210857532
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
96815
Advantage
76
Meryer (Shanghai) Chemical Technology Co., Ltd.
Tel
4006356688 18621169109
Fax
86-21-61259102
Email
market03@meryer.com
Country
China
ProdList
40228
Advantage
62
3B Pharmachem (Wuhan) International Co.,Ltd.
Tel
821-50328103-801 18930552037
Fax
86-21-50328109
Email
3bsc@sina.com
Country
China
ProdList
15838
Advantage
69
Alfa Aesar
Tel
400-6106006
Fax
021-67582001/03/05
Email
saleschina@alfa-asia.com
Country
China
ProdList
30123
Advantage
84
TCI (Shanghai) Development Co., Ltd.
Tel
021-67121386
Fax
021-67121385
Email
Sales-CN@TCIchemicals.com
Country
China
ProdList
24529
Advantage
81
Energy Chemical
Tel
021-021-58432009 400-005-6266
Fax
021-58436166
Email
sales8178@energy-chemical.com
Country
China
ProdList
44801
Advantage
61
Wuhan Chemwish Technology Co., Ltd
Tel
86-027-67849912
Fax
86-027-87531808
Email
sales@chemwish.com
Country
China
ProdList
35896
Advantage
56
Capot Chemical Co., Ltd
Tel
+86 (0) 571 85 58 67 18
Fax
0086-571-85864795
Country
China
ProdList
18207
Advantage
66
JinYan Chemicals(ShangHai) Co.,Ltd.
Tel
13817811078
Fax
86-021-50426522,50426273
Email
sales@jingyan-chemical.com
Country
China
ProdList
9976
Advantage
60
Shanghai Sinch Parmaceuticals Tech. Co. Ltd.
Tel
+86-21-54098501
Fax
+86-21-54096319
Email
sales@sinch.com.cn
Country
China
ProdList
11598
Advantage
64
Jia Xing Isenchem Co.,Ltd
Tel
0573-85285100 18627885956
Fax
0573-85285100
Email
isenchem@163.com
Country
China
ProdList
9309
Advantage
66
Adamas Reagent, Ltd.
Tel
400-6009262 16621234537
Fax
021-64823266
Email
chenyj@titansci.com
Country
China
ProdList
14101
Advantage
59
Shanghai Hanhong Scientific Co.,Ltd.
Tel
021-54306202 13764082696
Email
info@hanhongsci.com
Country
China
ProdList
42934
Advantage
64
Chemsky（shanghai）International Co.,Ltd.
Tel
021-50135380
Email
shchemsky@sina.com
Country
China
ProdList
32321
Advantage
50
Nanjing Lynsci Chemical Co., Ltd
Tel
+86-025-83208253 +86-13851694729
Fax
0086-25-83208253
Email
layefe@163.com
Country
China
ProdList
231
Advantage
62
skychemical Co.Ltd
Tel
021-20958197 20965099
Fax
021-20960837
Email
sales@skychemical.com
Country
China
ProdList
1183
Advantage
57
Nanjing Vital Chemical Co., Ltd.
Tel
Please Send Email 18652950785
Fax
025-87193546
Email
chemweiao@163.com
Country
China
ProdList
4378
Advantage
65
Tianjin Jinyuda Chemical Co., Ltd.
Tel
022-58013646 13011382049
Fax
022-23854368
Email
sales@jinyudachem.com
Country
China
ProdList
1930
Advantage
55
Shanghai ZaiQi Bio-Tech Co., Ltd.
Tel
021-54824098, 021-37212705 021-37212706, 13391256916
Fax
021-54824069
Email
sales@chemzq.com
Country
China
ProdList
570
Advantage
55
Shanghai civi chemical technology co.,Ltd
Tel
86-21-34053660
Fax
86-21-34053661
Email
sale@labgogo.com
Country
China
ProdList
9865
Advantage
52
Suzhou Sibian Chemical Technology Co.,Ltd.
Tel
0512-65617459 18915409046
Fax
0512-65617459
Email
sales@sibian-chem.com
Country
China
ProdList
1922
Advantage
55
Shanghai Topbiochem Technology Co., Ltd
Tel
+86-21-60341587
Fax
+86-21-61294319
Email
sales@topbiochem.com
Country
China
ProdList
6175
Advantage
58
Nanjing Norris-Pharm Technology Co., Ltd
Tel
18652989687
Fax
+86-25-52131256
Email
sales@norris-pharm.com
Country
China
ProdList
8878
Advantage
55
Jiangsu Aikon Biopharmaceutical R&D co.,Ltd.
Tel
025-66113011 17798518460
Fax
(1)02557626880
Email
cfzhang@aikonchem.com
Country
China
ProdList
19913
Advantage
55
SuZhou ShiYa Biopharmaceuticals, Inc.
Tel
86(512)5235 8471 17715136450
Fax
86(512)5235 6881
Email
sales@shiyabiopharm.com
Country
China
ProdList
4169
Advantage
58
Candia Thamtech Company Limited
Tel
0371-86615086 18203638366 0371-86159066 13526786601
Fax
0371-86159066
Country
China
ProdList
2015
Advantage
60
9ding chemical ( Shanghai) Limited
Tel
4009209199
Fax
86-021-52271987
Email
sales@9dingchem.com
Country
China
ProdList
18209
Advantage
56
Shanghai Aladdin Bio-Chem Technology Co.,LTD
Tel
400-6206333 13167063860
Fax
021-50323701
Email
anhua.mao@aladdin-e.com
Country
China
ProdList
25003
Advantage
65
Bsisun HK Imoprt And Export Company Limited
Tel
+86-18068513926
Fax
0086-519-85153711
Country
China
ProdList
1277
Advantage
55
Cantotech Chemicals, Ltd.
Tel
86-0755-86635001
Fax
86-0755-22642228
Email
cantotech@126.com
Country
China
ProdList
4566
Advantage
55
Shanghai Yolne Chemical Co., Ltd.
Tel
021-62960152
Fax
021-52212593
Email
934678158@qq.com
Country
China
ProdList
9899
Advantage
55
Chengdu AstaTech Trading Co., Ltd./AstaTech (Chengdu) Pharma. Co., Ltd.
Tel
+86-28-85122536 85324413
Fax
+86-28-85326443
Email
market@astatech.cn
Country
China
ProdList
8026
Advantage
55
Tianjin Chempharmatech Co.,Ltd.
Tel
022-66211079 13212288319
Fax
qq1405432731
Email
sales@chempharmatech.com
Country
China
ProdList
918
Advantage
55
Chimica Laboratories Co., Ltd
Tel
0086-573-82585213
Fax
0086-573-82585233
Email
bai@chimicalabs.com
Country
China
ProdList
861
Advantage
64
Aloespharm Co., Ltd.
Tel
021-20960837
Fax
021-20960837
Email
market@aloespharm.com
Country
China
ProdList
1302
Advantage
55
Shanghai Meishui Chemical Technology Co., Ltd
Tel
021-60549325 18616193163
Fax
021-33250306
Country
China
ProdList
4526
Advantage
56
Bide Pharmatech Ltd.
Tel
400-164-7117 13681763483
Fax
+86-21-61629029
Email
product02@bidepharm.com
Country
China
ProdList
39966
Advantage
60
Shanghai Worldyang Chemical Co.,Ltd.
Tel
021-021-56795766
Fax
+86-21-56795266
Email
sales@worldyachem.com
Country
China
ProdList
9476
Advantage
58
Chengdu HuaXia Chemical Reagent Co. Ltd
Tel
400-1166-196 13458535857
Fax
QQ：800101999
Email
cdhxsj@163.com
Country
China
ProdList
13350
Advantage
58
Wuxi Zhongkun Biochemical Technology Co., Ltd.
Tel
0510-85629785 18013409632
Fax
051085625359
Email
sales@reading-chemicals.com
Country
China
ProdList
15178
Advantage
58
Finetech Industry Limited
Tel
027-87465837 19945049750
Fax
027-8777-2287
Email
sales@finetechnology-ind.com
Country
China
ProdList
9637
Advantage
58
Modachem Shanghai Co., Ltd
Tel
+86 (0)21 51320687 51371369 1744605818
Fax
+86 (0)21 51371369
Country
China
ProdList
1578
Advantage
58
Credit-Chem Co., Ltd.
Tel
400-821-5857 021-64326257
Fax
021-64393586 QQ;2798200800
Email
credit-chem@foxmail.com
Country
China
ProdList
5219
Advantage
58
Shanghai YuLue Chemical Co., Ltd.
Tel
021-60345187 13671753212
Fax
021-34702061
Email
lzz841106@aliyun.com
Country
China
ProdList
10263
Advantage
55
Shanghai Jovan Biochemical Technology Co. Ltd.
Tel
+86-021-61654350
Fax
+86-021-61654350
Email
1245958370@qq.com
Country
China
ProdList
2982
Advantage
50
Shanghai Song Yuan Chemical Technology Co., Ltd.
Tel
010-1234567 18521000990
Fax
86-021-33275113
Email
sonyuanchemical@163.com
Country
China
ProdList
6479
Advantage
50
Nanjing Chalf-Pharm Technology Co., Ltd.
Tel
025-57018978 18251899859
Fax
025-57018008
Email
sales@chalf-pharm.com
Country
China
ProdList
5674
Advantage
50
Credit Asia Chemical Co., Ltd.
Tel
+86 (21) 61124340
Fax
+86 (21) 6129-4103
Country
China
ProdList
9756
Advantage
58
Cool Pharm, Ltd
Tel
021-60455363 18019463053
Fax
50966098
Email
sales@coolpharm.com
Country
China
ProdList
12346
Advantage
58
More
Less

View Lastest Price from 2-Cyano-3-chloropyridine manufacturers

Dideu Industries Group Limited
Product
2-Cyano-3-chloropyridine 38180-46-0
Price
US $1.10/g
Min. Order
1g
Purity
99.00%
Supply Ability
100 Tons Min
Release date
2021-10-14
Career Henan Chemical Co
Product
2-Cyano-3-chloropyridine 38180-46-0
Price
US $3.00/KG
Min. Order
1KG
Purity
98%
Supply Ability
1kg,5kg,50kg
Release date
2020-01-18
Career Henan Chemical Co
Product
2-Cyano-3-chloropyridine
Price
US $1.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
10000KGS
Release date
2020-01-02

38180-46-0, 2-Cyano-3-chloropyridineRelated Search:

2-Chloro-5-chloromethylpyridine Methylene dithiocyanate Clopidol 3-Aminopyridine ETHYL 2-CYANOACRYLATE Pentachloropyridine Epichlorohydrin 2-Cyanopyridine 3-Hydroxypyridine 3,5-Dichloro-2-cyanopyridine 5-Bromo-3-nitropyridine-2-carbonitrile 2-Cyano-3-fluoropyridine 5-bromo-3-methylpicolinonitrile 2-Cyano-3,5-difluoropyridine 3-bromo-5-chloropyridine-2-carbonitrile 5-bromo-3-chloropyridine-2-carbonitrile 5-Bromo-3-fluoro-pyridine-2-carbonitrile 2-Cyano-3-trifluoromethylpyridine

  • 2-Cyano-3-chloropyri
  • 3-Chloropicolinonitrile
  • 3-Chloro-2-cyanopyridine ,95%
  • 3-Chloro-2-cyanopyridine, 3-Chloropicolinonitrile
  • 3-CHLORO-2-PYRIDINECARBONITRILE
  • 3-CHLORO-2-CYANOPYRIDINE
  • 3-CHLOROPYRIDINE-2-CARBONITRILE
  • 2-CYANO-3-CHLORO PYRIDINE / 3-CHLORO-2-CYANOPYRIDINE
  • 2-CYANO-3-CHLOROPYRIDINE
  • 3-Chloro-2-cyanopyridine &gt
  • oro-2-cyanopyridine
  • 2-Pyridinecarbonitrile, 3-chloro-
  • 2-Cyano-3-chloropyridine ISO 9001：2015 REACH
  • 38180-46-0
  • Heterocycle-Pyridine series
  • Nucleotides and Nucleosides
  • Pyridines
  • Bases & Related Reagents
  • Pyridines, Pyrimidines, Purines and Pteredines
  • pharmacetical
  • Pyridine series
  • Pyridine
  • Nucleotides