2-Cyano-3-fluoropyridine

Product Name: 2-Cyano-3-fluoropyridine
CAS No.: 97509-75-6
Chemical Name: 2-Cyano-3-fluoropyridine
Synonyms: 3-FLUOROPICOLINONITRILE;3-Fluoropyridine-2-carbonitrile;3-FLUORO-2-PYRIDINECARBONITRILE;Rebamipide salt;2-CYANO-3-FLUOROPYRIDINE;2-Cyano-3-fluoropyridine >2-Cyano-3-fluoropyridine, 97+%;2-Pyridinecarbonitrile,3-fluoro-;3-Fluoropyridine-2-carbonitrile97%;3-Fluoropyridine-2-carbonitrile 97%
CBNumber: CB1765018
Molecular Formula: C6H3FN2
Formula Weight: 122.1
MOL File: 97509-75-6.mol

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2-Cyano-3-fluoropyridine Property

Melting point:: 27-30°C
Boiling point:: 120-125 °C(Press: 17 Torr)
Density: 1.24±0.1 g/cm3(Predicted)
Flash point:: 104 °C
storage temp.: Inert atmosphere,Room Temperature
solubility: Chloroform (Sparingly), DMSO (Slightly)
form: Solid
pka: -2.74±0.10(Predicted)
color: White to Off-White
InChI: InChI=1S/C6H3FN2/c7-5-2-1-3-9-6(5)4-8/h1-3H
InChIKey: VZFPSCNTFBJZHB-UHFFFAOYSA-N
SMILES: C1(C#N)=NC=CC=C1F
CAS DataBase Reference: 97509-75-6(CAS DataBase Reference)

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Safety

Hazard Codes: T,Xi,Xn
Risk Statements: 20/21/22-36/37/38-41-37/38
Safety Statements: 26-36/37/39-23
RIDADR: 3276
WGK Germany: 3
Hazard Note: Toxic
HazardClass: 6.1
PackingGroup: III
HS Code: 29333990

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H315Causes skin irritation

H318Causes serious eye damage

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 697109
Product name: 3-Fluoro-2-pyridinecarbonitrile
Purity: 96%
Packaging: 5g
Price: $75.6
Updated: 2025/07/31

Sigma-Aldrich

Product number: 697109
Product name: 3-Fluoro-2-pyridinecarbonitrile
Purity: 96%
Packaging: 1g
Price: $28.5
Updated: 2023/06/20

TCI Chemical

Product number: C2655
Product name: 2-Cyano-3-fluoropyridine
Purity: >98.0%(GC)
Packaging: 1g
Price: $17
Updated: 2025/07/31

TCI Chemical

Product number: C2655
Product name: 2-Cyano-3-fluoropyridine
Purity: >98.0%(GC)
Packaging: 5g
Price: $55
Updated: 2025/07/31

TRC

Product number: F621220
Product name: 3-Fluoropicolinonitrile
Packaging: 25g
Price: $225
Updated: 2021/12/16

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2-Cyano-3-fluoropyridine Chemical Properties,Usage,Production

Chemical Properties

Light yellow Cryst

Uses

2-Cyano-3-fluoropyridine is an organic intermediate that can be prepared from 3-fluoropyridine in three steps.

Synthesis

695-37-4

7677-24-9

97509-75-6

Using 3-fluoropyridine-N-oxide (Intermediate A, 2.85 g, 25.2 mmol) and trimethylcyanosilane (10.0 mL, 75.6 mmol) as raw materials, Intermediate A was dissolved in dichloromethane (25 ml) at room temperature, followed by addition of trimethylcyanosilane. The reaction mixture was heated to reflux for 10 hours. After completion of the reaction, it was cooled to room temperature and the reaction was quenched by the addition of saturated aqueous sodium bicarbonate solution (30 mL). The reaction mixture was extracted with dichloromethane (3 x 150 mL), the organic phases were combined and dried over anhydrous sodium sulfate. After filtration, the organic phase was concentrated under reduced pressure to give a light brown oily crude product (4.60 g). The crude product was purified by rapid column chromatography on silica gel, the eluent was hexane solution of 30% ethyl acetate to give a light brown oil, which solidified to light brown solid product B (2.48 g, 84% yield) after standing. The product was analyzed by HPLC with a retention time of 1.03 min.

References

[1] Patent: WO2003/90912, 2003, A1. Location in patent: Page/Page column 65
[2] Chemical and Pharmaceutical Bulletin, 1985, vol. 33, # 2, p. 565 - 571
[3] Patent: WO2006/12374, 2006, A1. Location in patent: Page/Page column 213
[4] Patent: US2004/77605, 2004, A1
[5] Patent: US2003/232842, 2003, A1. Location in patent: Page 7-8

2-Cyano-3-fluoropyridine Preparation Products And Raw materials

Raw materials

Preparation Products

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2-Cyano-3-fluoropyridine Suppliers

Americas 1 Belgium 2 Canada 1 China 247 Europe 2 France 1 Germany 6 India 9 Italy 1 Japan 2 Switzerland 1 The Netherlands 1 United Kingdom 7 United States 42 Global 323

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Energy Chemical

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View Lastest Price from 2-Cyano-3-fluoropyridine manufacturers

Shaanxi Dideu New Materials Co. Ltd

Product: 2-Cyano-3-fluoropyridine 97509-75-6
Price: US $0.00-0.00/KG
Min. Order: 1KG
Purity: 98.0%
Supply Ability: 10000KGS
Release date: 2025-06-04

WUHAN FORTUNA CHEMICAL CO., LTD

Product: 2-Cyano-3-fluoropyridine 97509-75-6
Price: US $0.00/KG
Min. Order: 1KG
Purity: 98%min
Supply Ability: 30tons/month
Release date: 2023-02-21

Shaanxi Dideu Medichem Co. Ltd

Product: 2-Cyano-3-fluoropyridine 97509-75-6
Price: US $1.10/g
Min. Order: 1g
Purity: 99.0% min
Supply Ability: 100 tons min
Release date: 2021-04-30

97509-75-6, 2-Cyano-3-fluoropyridineRelated Search:

2-Cyano-3,5-difluoropyridine 2-Fluoropyridine 3-Methylpicolinonitrile 3-Fluoropyridine Methylene dithiocyanate 3-Aminopyridine Sodium cyanoborohydride 2-Cyanopyridine 5-Bromo-3-fluoro-pyridine-2-carbonitrile 5-Bromo-3-nitropyridine-2-carbonitrile 5-bromo-3-methylpicolinonitrile 2-Cyano-3-chloropyridine 3-bromo-5-chloropyridine-2-carbonitrile 5-bromo-3-chloropyridine-2-carbonitrile 2-Cyano-3-trifluoromethylpyridine 5-Chloro-3-nitropyridine-2-carbonitrile 3,5-Dichloro-2-cyanopyridine 3-Bromo-5-methylpyridine-2-carbonitrile

3-FLUORO-2-PYRIDINECARBONITRILE

3-FLUOROPICOLINONITRILE

2-CYANO-3-FLUOROPYRIDINE

3-Fluoropyridine-2-carbonitrile

3-Fluoropyridine-2-carbonitrile 97%

3-Fluoropyridine-2-carbonitrile97%

2-CYANO-3-FLUOROPYRIDINE,3-FLUORO-2-PYRIDINECARBONITRILE

2-Cyano-3-fluoropyridine, 97+%

2-Pyridinecarbonitrile,3-fluoro-

3-Fluoro-2-pyridinecarbonitrile 96%

2-Cyano-3-fluoropyridine, 3-Fluoropicolinonitrile

2-Cyano-3-fluoropyridine &gt

2-Cyano-3-fluoropyridine ISO 9001：2015 REACH

97509-75-6 2-Cyano-3-fluoropyridine

Rebamipide salt

97509-75-6

975097-75-6

153126-31-3

Building Blocks

C5 to C6

C6 to C7

Chemical Synthesis

Fluorinated Building Blocks

Halogenated Heterocycles

Heterocyclic Building Blocks

Heterocyclic Fluorinated Building Blocks

Other Fluorinated Heterocycles

Pyridines

Pyridine series

cyanide| alkyl Fluorine