Synthesis
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2-Fluoropyridine

Synthesis
Product Name
2-Fluoropyridine
CAS No.
372-48-5
Chemical Name
2-Fluoropyridine
Synonyms
2-CYANOPHENYLBORONIC ACID;2-Fluoropyride;2-Fluorpyridin;2-FLUOROPYRIDINE;2-fluoro-pyridin;o-fluoropyridine;2-Fluoroypyridine;2-Fluorpyridin CAS;2-fluoride pyridine;Pyridine, 2-fluoro-
CBNumber
CB1461659
Molecular Formula
C5H4FN
Formula Weight
97.09
MOL File
372-48-5.mol
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2-Fluoropyridine Property

Boiling point:
126 °C/753 mmHg (lit.)
Density 
1.128 g/mL at 25 °C (lit.)
refractive index 
n20/D 1.466(lit.)
Flash point:
83 °F
storage temp. 
Inert atmosphere,2-8°C
form 
Liquid
pka
-0.44(at 25℃)
color 
Clear colorless to light yellow
Specific Gravity
1.13
Water Solubility 
Soluble in water.
BRN 
1515
Dielectric constant
37.289999999999999
InChI
InChI=1S/C5H4FN/c6-5-3-1-2-4-7-5/h1-4H
InChIKey
MTAODLNXWYIKSO-UHFFFAOYSA-N
SMILES
C1(F)=NC=CC=C1
CAS DataBase Reference
372-48-5(CAS DataBase Reference)
NIST Chemistry Reference
2-Fluoropyridine(372-48-5)
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Safety

Hazard Codes 
Xi,F,Xn
Risk Statements 
10-36/37/38-20/21/22
Safety Statements 
26-36-36/37/39-16
RIDADR 
UN 1993 3/PG 3
WGK Germany 
3
RTECS 
UT3900000
Hazard Note 
Flammable/Irritant
HazardClass 
3
PackingGroup 
III
HS Code 
29333999
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H226Flammable liquid and vapour

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P210Keep away from heat/sparks/open flames/hot surfaces. — No smoking.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
F15250
Product name
2-Fluoropyridine
Purity
98%
Packaging
10g
Price
$37.1
Updated
2024/03/01
Sigma-Aldrich
Product number
F15250
Product name
2-Fluoropyridine
Purity
98%
Packaging
100g
Price
$228
Updated
2024/03/01
TCI Chemical
Product number
F0217
Product name
2-Fluoropyridine
Purity
>98.0%(GC)
Packaging
25g
Price
$62
Updated
2024/03/01
TCI Chemical
Product number
F0217
Product name
2-Fluoropyridine
Purity
>98.0%(GC)
Packaging
100g
Price
$183
Updated
2024/03/01
Alfa Aesar
Product number
A11627
Product name
2-Fluoropyridine, 99%
Packaging
10g
Price
$36.65
Updated
2024/03/01
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2-Fluoropyridine Chemical Properties,Usage,Production

Synthesis

A rare example of fluorodenitration of a heterocyclic system was provided by 2- nitropyridine, which was converted to 2-fluoropyridine.

Chemical Properties

CLEAR COLOURLESS TO LIGHT YELLOW LIQUID

Uses

2-Fluoropyridine is a useful precursor of 2,3-disubstituted pyridines which is made by the possibility of metallation at C-3, together with the ready nucleophilic displacement of the activated fluorine. It can also react with thiophene to get 2-thiophen-2-yl-pyridine. It is used in the synthesis of aminopyridines.

2-Fluoropyridine Preparation Products And Raw materials

Raw materials

Preparation Products

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2-Fluoropyridine Suppliers

Shandong Vantage Specialty Chemicals Biotechnology Co., Ltd.
Tel
133-96369453 18678026865
Fax
0536-2101172
Email
sdfantai@163.com
Country
China
ProdList
852
Advantage
58
Chongqing Xingcan Pharmaceutical Technology Co., Ltd.
Tel
15523000485
Email
xingcanyaoye@sina.com
Country
China
ProdList
1686
Advantage
58
Fuxin Xin Kaida Fluorine Chemistry Co., Ltd.
Tel
0418-6566789 13464830066
Email
sales@xkdchem.com
Country
China
ProdList
169
Advantage
58
J & K SCIENTIFIC LTD.
Tel
010-82848833 400-666-7788
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
96815
Advantage
76
Meryer (Shanghai) Chemical Technology Co., Ltd.
Tel
4006608290; 18621169109
Fax
86-21-61259102
Email
market03@meryer.com
Country
China
ProdList
40241
Advantage
62
Liaoning Tianhua Chemical Co., Ltd.
Tel
0418-6530555 2855550
Fax
+86-418-6502885
Country
China
ProdList
338
Advantage
69
INTATRADE GmbH
Tel
+49 3493/605464
Fax
+49 3493/605470
Email
sales@intatrade.de
Country
Germany
ProdList
3576
Advantage
66
3B Pharmachem (Wuhan) International Co.,Ltd.
Tel
821-50328103-801 18930552037
Fax
86-21-50328109
Email
3bsc@sina.com
Country
China
ProdList
15848
Advantage
69
Alfa Aesar
Tel
400-6106006
Fax
021-67582001/03/05
Email
saleschina@alfa-asia.com
Country
China
ProdList
30132
Advantage
84
TCI (Shanghai) Development Co., Ltd.
Tel
021-67121386
Fax
021-67121385
Email
Sales-CN@TCIchemicals.com
Country
China
ProdList
24539
Advantage
81
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View Lastest Price from 2-Fluoropyridine manufacturers

Shaanxi Dideu Medichem Co. Ltd
Product
2-Fluoropyridine 372-48-5
Price
US $1.10/g
Min. Order
1g
Purity
99.0% min
Supply Ability
100 tons min
Release date
2021-05-26
LY Global chemicals co.,ltd .
Product
2-Fluoropyridine 372-48-5
Price
US $0.00-0.00/kg
Min. Order
1kg
Purity
98%
Supply Ability
500 kg
Release date
2023-03-08
Henan Aochuang Chemical Co.,Ltd.
Product
2-Fluoropyridine 372-48-5
Price
US $0.00-0.00/KG
Min. Order
1KG
Purity
98%
Supply Ability
1ton
Release date
2022-10-12

372-48-5, 2-FluoropyridineRelated Search:


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