Flupirtine

Product Name: Flupirtine
CAS No.: 56995-20-1
Chemical Name: Flupirtine
Synonyms: W2964;D-9998;W 2964;W-2964;Katadolon;Flupirtin;FLUPIRTINE;Flupirtinum;Trancopal Dolo;FLUPIRITNE MALEATE
CBNumber: CB6425140
Molecular Formula: C15H17FN4O2
Formula Weight: 304.32
MOL File: 56995-20-1.mol

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Flupirtine Property

Melting point:: 115-116°
Boiling point:: 445.15°C (rough estimate)
Density: 1.350±0.06 g/cm3(Predicted)
storage temp.: under inert gas (nitrogen or Argon) at 2–8 °C
solubility: Soluble in DMSO
form: Powder
pka: 12.19±0.70(Predicted)
Water Solubility: 1g/L(temperature not stated)

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Safety

Toxicity: LD50 orally in mice, rats: 617, 1660 mg/kg (Jakovlev)

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H312Harmful in contact with skin

H332Harmful if inhaled

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 44783
Product name: Flupirtine
Purity: analytical standard
Packaging: 25MG
Price: $265
Updated: 2022/05/15

American Custom Chemicals Corporation

Product number: API0015265
Product name: FLUPIRTINE
Purity: 95.00%
Packaging: 100G
Price: $253.05
Updated: 2021/12/16

Biorbyt Ltd

Product number: orb611670
Product name: Flupirtine
Packaging: 100mg
Price: $510
Updated: 2021/12/16

Biorbyt Ltd

Product number: orb611670
Product name: Flupirtine
Packaging: 250mg
Price: $765
Updated: 2021/12/16

Matrix Scientific

Product number: 179894
Product name: Carbamic acid
Purity: [2-oxo-2-(2-propynylamino)ethoxy]-1,1-dimethylethyl ester95%
Packaging: 1g
Price: $826
Updated: 2021/12/16

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Flupirtine Chemical Properties,Usage,Production

Chemical Properties

Crystallized from isopropanol, melting point 115-116°C. 5% ethanol solution is colorless, but turns green after exposure to air for 20h. Acute toxicity LD50 mice, rats (mg/kg): 617, 1660 oral. Flupirtine Hydrochloride (Flupirtine Hydrochloride): C15 H17FN4O2?HCl. crystallized from water, melting point 214-215°C. Flupirtine Maleate (Flupirtine Maleate): C15H17FN4O2?C4H4O4.[75507-68-5]. Colorless crystals from isopropanol, melting point 175.5 to 176°C. A mixture of crystalline A and B; preferably containing 60%-90% A.

Uses

Analgesic.

Uses

Therapeutic use of Flupirtine was discontinued due to drug induced liver injury (DILI). Since the mechanism of action is not related to its adverse effects, it is important to focus on chemical modifications.

Definition

ChEBI: N-[2-amino-6-[(4-fluorophenyl)methylamino]-3-pyridinyl]carbamic acid ethyl ester is an aminopyridine.

Clinical Use

Flupirtine maleate is an analgesic with an unknown mode of action. It is used in single doses of 100 mg orally and 150 mg rectally for the treatment of different pain conditions.

Flupirtine Preparation Products And Raw materials

Raw materials

2-Amino-6-chloro-3-nitropyridine Flupirtine maleate Maleic acid 4-Fluorobenzylamine Ethyl chloroformate

Preparation Products

Fluroxypyr

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Flupirtine Suppliers

China 63 Europe 3 Germany 1 India 5 United Kingdom 1 United States 13 Global 86

LGM Pharma

Tel: 1-(800)-881-8210
Fax: 615-250-9817
Email: inquiries@lgmpharma.com
Country: United States
ProdList: 2123
Advantage: 70

Shanghai Everchem Co., Ltd

Tel: 86-29-81325371
Fax: +86-29-81325373
Email: info@everchem.cn
Country: China
ProdList: 84
Advantage: 62

Wisdom Pharmaceutical Co., Ltd.

Tel: 0086-15189180296
Fax: 0086-513-81292226
Email: l_xu@wisdompharma.com
Country: China
ProdList: 221
Advantage: 60

Artis Chemistry (Shanghai) Co. Ltd.

Tel: 86-21-60936353
Fax: 86-21-60936352
Country: China
ProdList: 335
Advantage: 58

Shanghai T&W Pharmaceutical Co., Ltd.

Tel: +86 21 61551611
Fax: +86 21 50676805
Country: China
ProdList: 9891
Advantage: 58

Hubei XinyuanShun Chemical Co., Ltd.

Tel: 13971561712, 13995564702, 027-50664929
Fax: 027-50664927
Email: hbeixys2001@163.com
Country: China
ProdList: 3120
Advantage: 55

3B Scientific (Wuhan) Corporation Limited

Tel: 027-88063677 18971314022;
Fax: 027-88063656
Email: sales@3bsc.com
Country: China
ProdList: 294
Advantage: 58

Chizhou Kailong Import and Export Trade Co., Ltd.

Tel
Fax: -
Email: xg01_gj@163.com
Country: China
ProdList: 9484
Advantage: 50

Shanghai RenYue Chemical Technology Co., Ltd.

Tel: 021-62219190; 18321139117
Email: 316441092@qq.com
Country: China
ProdList: 2905
Advantage: 55

Shanghai YuanYe Biotechnology Co., Ltd.

Tel: 021-61312847; 18021002903
Fax: QQ:3008007432
Email: 3008007409@qq.com
Country: China
ProdList: 71826
Advantage: 60

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View Lastest Price from Flupirtine manufacturers

Moxin Chemicals

Product: Flupirtine 56995-20-1
Price: US $0.00-0.00/mg
Min. Order: 10mg
Purity: 95%+
Supply Ability: 10000000
Release date: 2025-02-24

Zhuozhou Wenxi import and Export Co., Ltd

Product: Flupirtine 56995-20-1
Price: US $15.00-10.00/KG
Min. Order: 1KG
Purity: 99%+ HPLC
Supply Ability: Monthly supply of 1 ton
Release date: 2021-07-10

Zhuozhou Wenxi import and Export Co., Ltd

Product: Flupirtine 56995-20-1
Price: US $15.00-10.00/KG
Min. Order: 1KG
Purity: 99%+ HPLC
Supply Ability: Monthly supply of 1 ton
Release date: 2021-07-09

56995-20-1, FlupirtineRelated Search:

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FLUPIRTINE

D-9998

Katadolon

Ethyl N-[2-amino-6-[(4-fluorophenyl)methylamino]pyridin-3-yl]carbamate

FLUPIRITNE MALEATE

[2-Amino-6-[[(4-fluorophenyl)methyllaminol-3-pyridinyl]carbamic acid ethyl ester

Flupirtine (D-9998)

Flupirtin

Carbamic acid, [2-amino-6-[[(4-fluorophenyl)methyl]amino]-3-pyridinyl]-, ethyl ester

Carbamic acid, N-[2-amino-6-[[(4-fluorophenyl)methyl]amino]-3-pyridinyl]-, ethyl ester

Trancopal Dolo

N-[2-Amino-6-[(p-fluorobenzyl)amino]-3-pyridinyl]carbamic acid ethyl ester

N-Acetylated Flupirtine

FlupirtineQ: What is Flupirtine Q: What is the CAS Number of Flupirtine Q: What is the storage condition of Flupirtine Q: What are the applications of Flupirtine

Flupirtinum

W 2964

W2964

W-2964

Ethyl (2-amino-6-((4-fluorobenzyl)amino)pyridin-3-yl)carbamate

56995-20-1

C15H17FN4O2