Physicochemical properties Toxicity Mechanism of action Applicable crops Prevention and control object Usage method Preparation method Analysis method
ChemicalBook > CAS DataBase List > Chlorpropham

Chlorpropham

Physicochemical properties Toxicity Mechanism of action Applicable crops Prevention and control object Usage method Preparation method Analysis method
Product Name
Chlorpropham
CAS No.
101-21-3
Chemical Name
Chlorpropham
Synonyms
CIPC;CHLOROPROPHAM;y3;Y 3;CICP;DECCO;budnip;ci-ifk;CI-IPC;Cl-IFK
CBNumber
CB3136324
Molecular Formula
C10H12ClNO2
Formula Weight
213.66
MOL File
101-21-3.mol
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Chlorpropham Property

Melting point:
41°C
Boiling point:
247°C
Density 
1.18
refractive index 
nD20 1.5388
Flash point:
247°C
storage temp. 
2-8°C
solubility 
Chloroform (Slightly), Methanol (Slightly)
form 
crystalline
pka
13.06±0.70(Predicted)
color 
light tan
Odor
faint char. odor
Water Solubility 
0.009 g/100 ml very poor
Decomposition 
247 ºC
Merck 
14,2187
BRN 
2211397
Exposure limits
An experimental carcinogen and neoplastigen
Stability:
Stable. Incompatible with strong acids, strong bases, strong oxidizing agents.
CAS DataBase Reference
101-21-3(CAS DataBase Reference)
IARC
3 (Vol. 12, Sup 7) 1987
NIST Chemistry Reference
Chlorpropham(101-21-3)
EPA Substance Registry System
Chlorpropham (101-21-3)
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Safety

Hazard Codes 
Xn,N,F
Risk Statements 
22-51/53-36-20/21/22-11
Safety Statements 
61-36/37-26-16
RIDADR 
UN 3077 9/PG 3
WGK Germany 
2
RTECS 
FD8050000
HS Code 
2924.29.4300
HazardClass 
9
PackingGroup 
III
Hazardous Substances Data
101-21-3(Hazardous Substances Data)
Toxicity
LD50 orally in rats: 1.2 g/kg (Boyd, Carsky)
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H351Suspected of causing cancer

H373May cause damage to organs through prolonged or repeated exposure

H411Toxic to aquatic life with long lasting effects

Precautionary statements

P201Obtain special instructions before use.

P202Do not handle until all safety precautions have been read and understood.

P260Do not breathe dust/fume/gas/mist/vapours/spray.

P273Avoid release to the environment.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P308+P313IF exposed or concerned: Get medical advice/attention.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
CRM43551
Product name
Chlorpropham
Purity
certified reference material, TraceCERT?
Packaging
100MG
Price
$139
Updated
2024/03/01
Sigma-Aldrich
Product number
45393
Product name
Chlorpropham
Purity
PESTANAL
Packaging
250mg
Price
$35.1
Updated
2024/03/01
TCI Chemical
Product number
C2555
Product name
Chlorpropham
Packaging
1G
Price
$36
Updated
2024/03/01
TCI Chemical
Product number
C2555
Product name
Chlorpropham
Packaging
25G
Price
$120
Updated
2024/03/01
TRC
Product number
C424905
Product name
Chlorpropham
Packaging
10g
Price
$100
Updated
2021/12/16
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Chlorpropham Chemical Properties,Usage,Production

Physicochemical properties

A solid with low melting point of 41.4 ℃. The density is d30 1.180 and the refractive index is nD20 (after cooling) 1.5395.At 25 C, the solubility in the water is 89mg/L, and the degree of melting in the oil is medium (10% in the kerosene). It can be mixed with the lower alcohols, aromatics and most organic solvents. The purity of the industrial product is 98.5%, and the melting point is 38.5 ~ 40℃. Stable at lower than 100 C, but slowly hydrolyzed in acid and alkaline medium.

Toxicity

The acute oral administration of LD50 is 5 ~ 7.5g/kg in rats, and the acute oral administration is 5g/kg in rabbits. The drug had no toxic effect on rabbit skin for 20 hours or 2g/ kg feed for rats and dogs for 2 years. The acute oral administration is LD50>2g/kg for wild ducks. The TLm (48 hours) of goldfish and carp (48 hours) is 10 ~ 40mg/L.

Mechanism of action

Mitotic inhibitor, in many perennial crops and some annual crops, it can be used alone or with other herbicides as pre-emergent selective weed removal. It is a plant growth regulator as well as a herbicide. It inhibits the activity of beta amylase, inhibits the synthesis of RNA and protein, interferes with oxidative phosphorylation and photosynthesis, and destroys cell division. Chloraniline is volatile. The steam can be absorbed by the bud in order to suppress weed bud growth. The residual effect in soil was longer than that of aniline, and the selectivity for some crops was smaller than that of aniline. In addition, it also regulates the growth of plants. It is used to inhibit the germination of potatoes during storage, flower and fruit thinning etc..

Applicable crops

Alfalfa, wheat, corn, soybean, sunflower, potato, sugar beet, rice, carrots, spinach, onions, etc..

Prevention and control object

Annual grasses and certain broadleaf weeds including ryegrass, barnyard grass, bluegrass, purslane, chickweed and Tusizi etc. annual grasses and certain broadleaf weeds.

Usage method

The amount of effective components is 2.24 ~ 4.5kg per hectare per hectare below 16 C in pre seedling soil treatment. Double the amount above 24 centigrade and mix soil after application. The post seedling treatment is 1.2 ~ 3.5kg. For the post seedling treatment, the activity of herbicide is poor. But it can control amaranth and Polygonum, chickweed and purslane in the seedling. As a growth regulator, it is used to inhibit the germination of potatoes.

Preparation method

It can be made by reaction of inter - Chloroaniline and isopropyl chloroformate or isopropanol and ISO - chlorophenyl isocyanate.

Analysis method

Determine the CO2 produced by acidolysis.
Residue determination:
(1) The H2SO4 is hydrolyzed of 1:1 by the extraction of two hydrogen methane, and the alkali is obtained. The 3- hydrogen aniline is vaporized and the colorimetric determination is carried out by the hypochlorite - phenol method.
(2) Infrared spectroscopy.

Chemical Properties

beige to brown solid

Uses

Preemergent and postemergent herbicide used to regulate plant growth and control of weeds in carrot, onion, garlic and other crops

Uses

Chlorpropham is particularly useful in agricultural settings. It is used in pesticide products for treatment of plants and soil.

Uses

Herbicide; plant growth regulator.

Definition

ChEBI: A carbamate ester that is the isopropyl ester of 3-chlorophenylcarbamic acid.

General Description

Brown chunky solid.

Air & Water Reactions

Insoluble in water.

Reactivity Profile

Chlorpropham is a carbamate ester. Carbamates are chemically similar to, but more reactive than amides. Like amides they form polymers such as polyurethane resins. Carbamates are incompatible with strong acids and bases, and especially incompatible with strong reducing agents such as hydrides. Flammable gaseous hydrogen is produced by the combination of active metals or nitrides with carbamates. Strongly oxidizing acids, peroxides, and hydroperoxides are incompatible with carbamates.

Hazard

Toxic by ingestion.

Fire Hazard

Flash point data for Chlorpropham are not available, however Chlorpropham is probably combustible.

Agricultural Uses

Herbicide, Plant growth regulator: Chlorpropham is a plant growth regulator that is used primarily in the U.S. to inhibit post-harvest potato sprouting. Other uses include pre-emergence control of grass weeds in alfalfa, beans, blueberries, cane berries, carrots, cranberries, ladino clover, garlic, seed grass, onions, spinach, sugar beets, tomatoes, safflower, soybeans, gladioli and woody nursery stock. It is used to control suckers in tobacco

Trade name

ATLAS® CIPC 40; BEET-KLEEN® (with Fenuron® and isopropyl carbanilate); BUDNIP®; CAMPBELL’S® CIPC 40%; CHLORO IPC®; ELBANIL®; FASCO® WY-HOE; FURLOE®; FURLOE® 4EC; JACK WILSON® CHLORO 51 (OIL); LIRO METOXON®; MIRVALE®; MORCRAN® (with n-1-naphthylphthalamic acid); MSS® CICP; NEXOVAL®; PREVENOL® 56; PREVENTOL®; PREVENTOL® 56; PREWEED®; RESIDUREN®; RESIDUREN® EXTRA; SPROUT NIP®; SPROUT-NIP® EC; SPUDNIC®; SPUD-NIE®; STOPGERME®-S; TATERPEX®; TRIPEC® (with carbamic acid, phenyl-, 1-methylethyl ester); TRIHERBICIDE® CIPC; UNICROP® CIPC; WAREFOG®; Y3®

Environmental Fate

Soil. Hydrolyzes in soil forming 3-chloroaniline (Bartha, 1971; Hartley and Kidd, 1987; Smith, 1988; Rajagopal et al., 1989). In soil, Pseudomonas striata Chester, a Flavobacterium sp., an Agrobacterium sp. and an Achromobacter sp. readily degraded chlorpropham to 3-chloroaniline and 2-propanol. Subsequent degradation by enzymatic hydrolysis yielded carbon dioxide, chloride ions and unidentified compounds (Kaufman, 1967; Rajagopal et al., 1989). Hydrolysis products that may form in soil and in microbial cultures include N-phenyl-3-chlorocarbamic acid, 3-chloroaniline, 2-amino-4-chlorophenol, monoisopropyl carbonate, 2-propanol, carbon dioxide and condensation products (Rajagopal et al., 1989). The reported half-lives in soil at 15 and 29°C are 65 and 30 days, respectively (Hartley and Kidd, 1987)
Plant. Chlorpropham is rapidly metabolized in plants (Ashton and Monaco, 1991). Metabolites identified in soybean plants include isopropyl-N-4-hydroxy-3-chlorophenylcarbamate, 1-hydroxy-2-propyl-3′-chlorocarbanilate and isopropyl-N-5-chloro-2-hy
Photolytic. The photodegradation rate of chlorpropham in aqueous solution was enhanced in the presence of a surfactant (TMN-10) (Tanaka et al., 1981). In a later study, Tanaka et al. (1985) studied the photolysis of chlorpropham (50 mg/L) in aque
Chemical/Physical. Emits toxic phosgene fumes when heated to decomposition (Sax and Lewis, 1987). In a 0.50 N sodium hydroxide solution at 20°C, chlorpropham was hydrolyzed to aniline derivatives. The half-life of this reaction was 3.5 days (El-Dib and Aly, 1976). Simple hydrolysis leads to the formation of 3-chlorophenylcarbamic acid and 2-propanol. The acid is very unstable and is spontaneously converted to 3-chloroaniline and carbon dioxide (Still and Herrett, 1976)

Chlorpropham Preparation Products And Raw materials

Raw materials

Preparation Products

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Chlorpropham Suppliers

Maikeshi (East) Ltd.
Tel
0571-28007828
Fax
86-513-84814078 86-571-85225083
Email
max@maxchemicals.com
Country
China
ProdList
58
Advantage
34
Wuhan Yuqing Jiaheng Pharmaceutical Co., Ltd
Tel
027-83855310 13476018176
Fax
13476018176
Email
408614617@qq.com
Country
China
ProdList
909
Advantage
58
J & K SCIENTIFIC LTD.
Tel
010-82848833 400-666-7788
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
96815
Advantage
76
TAIYUAN RHF CO.,LTD.
Tel
+86 351 7031519
Fax
+86 351 7031519
Email
sales@RHFChem.com
Country
China
ProdList
2341
Advantage
56
Energy Chemical
Tel
021-021-58432009 400-005-6266
Fax
021-58436166
Email
sales8178@energy-chemical.com
Country
China
ProdList
44751
Advantage
61
Nanjing Chemlin Chemical Co., Ltd
Tel
025-83697070 13913916777;
Fax
+86-25-83453306
Email
info@chemlin.com.cn
Country
China
ProdList
17839
Advantage
64
Shanghai Hanhong Scientific Co.,Ltd.
Tel
021-54306202 13764082696;
Email
info@hanhongsci.com
Country
China
ProdList
42982
Advantage
64
Syntechem Co.,Ltd
Tel
Fax
E-Mail Inquiry
Email
info@syntechem.com
Country
China
ProdList
12990
Advantage
57
BEST-REAGENT
Tel
400-1166-196 18981987031
Fax
028-84555506 800101999
Email
cdhxsj@163.com
Country
China
ProdList
11726
Advantage
57
China Langchem Inc.
Tel
0086-21-58956006
Fax
0086-21-58956100
Country
China
ProdList
7815
Advantage
57
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View Lastest Price from Chlorpropham manufacturers

Hebei Duling International Trade Co. LTD
Product
Chlorpropham 101-21-3
Price
US $100.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
100 tons
Release date
2023-05-15
Wuhan Boyuan Import & Export Co., LTD
Product
Chlorpropham 98.5%/99%TC,25%EC,CAS NO.101-21-3 101-21-3
Price
US $1.00/G
Min. Order
100G
Purity
99.9%
Supply Ability
50000 tons
Release date
2018-10-30
Hebei Mojin Biotechnology Co., Ltd
Product
Chlorpropham 101-21-3
Price
US $0.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
50000KG/month
Release date
2023-09-08

101-21-3, ChlorprophamRelated Search:


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