p-Anisohydrazide
- Product Name
- p-Anisohydrazide
- CAS No.
- 3290-99-1
- Chemical Name
- p-Anisohydrazide
- Synonyms
- AKOS 92185;anisichydrazide;p-anisohydrazide;anisoylhydrazine;AKOS BBS-00004504;P-ANISOYLHYDRAZINE;P-ANISIC HYDRAZIDE;anisicacidhydrazide;LABOTEST-BB LT00025103;4-METHOXYBENZHYDRAZIDE
- CBNumber
- CB3128224
- Molecular Formula
- C8H10N2O2
- Formula Weight
- 166.18
- MOL File
- 3290-99-1.mol
p-Anisohydrazide Property
- Melting point:
- 136-140 °C(lit.)
- Boiling point:
- 294.38°C (rough estimate)
- Density
- 1.2265 (rough estimate)
- refractive index
- 1.6180 (estimate)
- storage temp.
- Sealed in dry,Room Temperature
- form
- powder to crystal
- pka
- 12.65±0.10(Predicted)
- color
- White to Orange to Green
- Water Solubility
- Slightly soluble in water.
- BRN
- 389017
- InChIKey
- REKQLYUAUXYJSZ-UHFFFAOYSA-N
- CAS DataBase Reference
- 3290-99-1(CAS DataBase Reference)
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- 558346
- Product name
- 4-Methoxybenzhydrazide
- Purity
- 97%
- Packaging
- 5g
- Price
- $21.85
- Updated
- 2025/07/31
- Product number
- 558346
- Product name
- 4-Methoxybenzhydrazide
- Purity
- 97%
- Packaging
- 25g
- Price
- $78.1
- Updated
- 2025/07/31
- Product number
- M1770
- Product name
- 4-Methoxybenzohydrazide
- Purity
- >98.0%(GC)(T)
- Packaging
- 5g
- Price
- $91
- Updated
- 2025/07/31
- Product number
- M1770
- Product name
- 4-Methoxybenzohydrazide
- Purity
- >98.0%(GC)(T)
- Packaging
- 25g
- Price
- $235
- Updated
- 2025/07/31
- Product number
- M292953
- Product name
- 4-Methoxybenzhydrazide
- Packaging
- 500mg
- Price
- $45
- Updated
- 2021/12/16
p-Anisohydrazide Chemical Properties,Usage,Production
Uses
4-Methoxybenzhydrazide is used as pharmaceutical intermediates and it is also involved in a variety of organic synthesis.
Uses
4-Methoxybenzhydrazide may be used to synthesize:
- N′-[(E)-5-bromo-2-hydroxy-3-methoxybenzylidene]-4-methoxybenzohydrazide monohydrate
- 2,5-bis(4-methoxyphenyl)-1,3,4-oxadiazole
- hydrazone ligands, which readily forms ruthenium(II) hydrazone complexes via reaction with [RuHCl(CO)(PPh3)3]
Synthesis Reference(s)
Journal of Medicinal Chemistry, 27, p. 1565, 1984 DOI: 10.1021/jm00378a007
Safety Profile
Poison by intravenous route. Questionable carcinogen with experimental neoplastigenic data. When heated to decomposition it emits toxic fumes of Nox.
Synthesis
121-98-2
3290-99-1
4-Methoxybenzoic acid hydrazide was synthesized according to literature [22]. A mixture of methyl 4-methoxybenzoate (1.66 g, 10 mmol) with 80% hydrazine hydrate (3.6 mL, 60 mmol) in anhydrous ethanol (20 mL) was heated and refluxed for 6 hours. After completion of the reaction, the solvent was removed by distillation under reduced pressure to give a white precipitate. The crude product was recrystallized from anhydrous ethanol to give 4-methoxybenzohydrazide as colorless needle-like crystals. Yield 96%, melting point 138-139°C (literature values in accordance).
References
[1] Journal of the American Chemical Society, 2013, vol. 135, # 15, p. 5656 - 5668
[2] Journal of the Chilean Chemical Society, 2012, vol. 57, # 4, p. 1492 - 1496
[3] Spectrochimica Acta - Part A: Molecular and Biomolecular Spectroscopy, 2017, vol. 174, p. 272 - 278
[4] European Journal of Medicinal Chemistry, 1985, vol. 20, # 3, p. 257 - 266
[5] Bioorganic and Medicinal Chemistry, 2005, vol. 13, # 16, p. 4842 - 4850
p-Anisohydrazide Preparation Products And Raw materials
Raw materials
Preparation Products
p-Anisohydrazide Suppliers
- Tel
- --
- Fax
- --
- y.barysheva@ukrorgsynth.com
- Country
- Ukraine
- ProdList
- 6230
- Advantage
- 38
View Lastest Price from p-Anisohydrazide manufacturers
- Product
- p-Anisohydrazide 3290-99-1
- Price
- US $1.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 20T
- Release date
- 2024-07-11
- Product
- p-Anisohydrazide 3290-99-1
- Price
- US $1.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- Customized
- Release date
- 2019-07-02