curvularin

Product Name: curvularin
CAS No.: 10140-70-2
Chemical Name: curvularin
Synonyms: curvularin;(S)-Curvularin;S-Curvularin, NSC 166071;2H-3-Benzoxacyclododecin-2,10(1H)-dione, 4,5,6,7,8,9-hexahydro-11,13-dihydroxy-4-methyl-,(4S)-
CBNumber: CB31341734
Molecular Formula: C16H20O5
Formula Weight: 292.33
MOL File: 10140-70-2.mol

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curvularin Property

Melting point:: 206-206.5°
alpha: D18 -36.3° (c = 3.8 in ethanol)
Boiling point:: 557.0±29.0 °C(Predicted)
Density: 1.200±0.06 g/cm3(Predicted)
storage temp.: -20°C
solubility: DMSO: soluble1mg/mL
form: powder
pka: 7.58±0.40(Predicted)
color: Off-white

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Safety

Hazard Codes: Xn
Risk Statements: 22
WGK Germany: 3
HS Code: 29419000

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P330Rinse mouth.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: SML0772
Product name: Curvularin
Purity: from
Packaging: 5mg
Price: $205.6
Updated: 2024/03/01

Sigma-Aldrich

Product number: SML0772
Product name: Curvularin
Purity: from
Packaging: 1mg
Price: $109
Updated: 2022/05/15

Cayman Chemical

Product number: 21758
Product name: Curvularin
Purity: ≥98%
Packaging: 1mg
Price: $73
Updated: 2024/03/01

Cayman Chemical

Product number: 21758
Product name: Curvularin
Purity: ≥98%
Packaging: 5mg
Price: $270
Updated: 2024/03/01

TRC

Product number: C844503
Product name: Curvularin
Packaging: 1mg
Price: $50
Updated: 2021/12/16

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curvularin Chemical Properties,Usage,Production

Uses

Curvularin is a 12-membered macrocyclic lactone incorporating a resorcinyl moiety, produced by a number of fungal species, including Curvularia, Penicillium and Alternaria. Curvularin exhibits a distinctly different biological profile to the structurally similar resorcylic acid lactones such as the zearalenones, radicicol and LL Z1640-2. Curvularin inhibits cell division by disrupting mitotic spindle formation and is known to be phytotoxic. More recent investigations have shown that curvularin is a highly selective transcription-based inhibitor of iNOS-dependent NO production, acting on the Janus tyrosine kinase-STAT pathway. This action offers an approach to the development of drugs inhibiting iNOS overproduction associated with NO pathophysiology.

Uses

Curvularin is a potent antifungal and mycotoxin that also inhibits NO production.

storage

+4°C

curvularin Preparation Products And Raw materials

Raw materials

Preparation Products

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curvularin Suppliers

China 44 India 1 United Kingdom 2 United States 7 Global 54

Shanghai EFE Biological Technology Co., Ltd.

Tel: 021-65675885 18964387627
Fax: 021-65675885
Email: info@efebio.com
Country: China
ProdList: 9709
Advantage: 58

Lynnchem

Tel: 86-(0)29-85992781 17792393971
Email: info@lynnchem.com
Country: China
ProdList: 4587
Advantage: 58

Novachemistry

Tel: 44-20819178-90 02081917890
Fax: (0)2080432064
Email: info@novachemistry.com
Country: United Kingdom
ProdList: 4381
Advantage: 58

Shenzhen Polymeri Biochemical Technology Co., Ltd.

Tel: +86-400-002-6226 13028896684
Email: sales@rrkchem.com
Country: China
ProdList: 55896
Advantage: 58

BOC Sciences

Tel: +16314854226
Email: inquiry@bocsci.com
Country: United States
ProdList: 19743
Advantage: 58

TargetMol Chemicals Inc.

Tel: +1-781-999-5354 +1-00000000000
Email: marketing@targetmol.com
Country: United States
ProdList: 19892
Advantage: 58

Career Henan Chemica Co

Tel: +86-0371-86658258 15093356674;
Fax: 0371-86658258
Email: laboratory@coreychem.com
Country: China
ProdList: 30255
Advantage: 58

ChemeGen(Shanghai) Biotechnology Co.,Ltd.

Tel: 18818260767
Fax: QQ 3610331285
Email: sales@chemegen.com
Country: China
ProdList: 11289
Advantage: 58

BioBioPha Co., Ltd.

Tel: 0871-65217109
Fax: 0871-65215563
Email: y.liu@mail.biobiopha.com
Country: China
ProdList: 1388
Advantage: 58

Shaanxi Dideu Medichem Co. Ltd

Tel: 029-61856359 18690052321
Fax: 029-88380327
Email: 1027@dideu.com
Country: China
ProdList: 10010
Advantage: 58

10140-70-2, curvularinRelated Search:

NYSTATIN A1 TRIHYDRATE curvularin 4-Hexanoylresorcinol Methyl 3,5-dihydroxyphenylacetate

curvularin

2H-3-Benzoxacyclododecin-2,10(1H)-dione, 4,5,6,7,8,9-hexahydro-11,13-dihydroxy-4-methyl-,(4S)-

S-Curvularin, NSC 166071

(S)-Curvularin

10140-70-2

Antibiotic