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BETA-CYANO-L-ALANINE

Product Name
BETA-CYANO-L-ALANINE
CAS No.
6232-19-5
Chemical Name
BETA-CYANO-L-ALANINE
Synonyms
H-CPA-OH;3-CYANO-L-ALANINE;(S)-2-Amino-3-cyanopropanoic acid;L-CNAla;H-ALA(3-CN)-OH;H-b-Cyano-Ala-OH;H-β-Cyano-Ala-OH;β-Cyano-L-Ala-OH;H-β-Cyano-Ala-OH;B-cyano-L-alanine
CBNumber
CB3134375
Molecular Formula
C4H6N2O2
Formula Weight
114.1
MOL File
6232-19-5.mol
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BETA-CYANO-L-ALANINE Property

Melting point:
217 °C
storage temp. 
-20°C
solubility 
PBS (pH 7.2): 10 mg/ml
form 
A crystalline solid
color 
White to yellow
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Safety

WGK Germany 
3
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
C9650
Product name
β-Cyano-L-alanine
Purity
≥95%
Packaging
250mg
Price
$611
Updated
2024/03/01
Cayman Chemical
Product number
10010947
Product name
β-cyano-L-Alanine
Purity
≥98%
Packaging
10mg
Price
$9
Updated
2024/03/01
Cayman Chemical
Product number
10010947
Product name
β-cyano-L-Alanine
Purity
≥98%
Packaging
50mg
Price
$30
Updated
2024/03/01
Cayman Chemical
Product number
10010947
Product name
β-cyano-L-Alanine
Purity
≥98%
Packaging
100mg
Price
$50
Updated
2024/03/01
Cayman Chemical
Product number
10010947
Product name
β-cyano-L-Alanine
Purity
≥98%
Packaging
250mg
Price
$109
Updated
2024/03/01
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BETA-CYANO-L-ALANINE Chemical Properties,Usage,Production

Description

Hydrogen sulfide (H2S) is a naturally-occurring gasotransmitter with vasodilator and inflammatory modulating activity. H2S is synthesized naturally in a range of mammalian tissues principally by the activity of two enzymes, cystathionine γ lyase (CSE) and cystathionine β synthetase (CBS). β-cyano-L-Alanine (BCA) is a reversible inhibitor of the H2S-synthesizing enzyme CSE. BCA blocks H2S synthesis in rat liver preparations with an IC50 value of 6.5 μM and increases blood pressure in anaesthetized rats induced with hemorrhagic shock by inhibiting endogenous H2S synthesis. BCA at 50 mg/kg blocked both L-cysteine- and LPS-induced hyperalgesia in rats.

Chemical Properties

White to off-white powder

Uses

β-L-cyanoalanine is an amino acid that promotes seed germination in A. albus seeds. Beta-Cyano-L-alanine in the diet of adult locusts causes a decrease in the hemolymph volume thereby affecting water balance responses. L-β-cyanoalanine is an inhibitor of vitamin B6.

Definition

ChEBI: A cyanoamino acid that is the 3-cyano-derivative of L-alanine.

Biochem/physiol Actions

β-Cyano-L-alanine (BCA) is used as a cystathione γ-lyase (CSE) inhibitor to study the physiological roles of hydrogen sulfide in processes such as angiogenesis and hypertension.

BETA-CYANO-L-ALANINE Preparation Products And Raw materials

Raw materials

Preparation Products

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BETA-CYANO-L-ALANINE Suppliers

3B Pharmachem (Wuhan) International Co.,Ltd.
Tel
821-50328103-801 18930552037
Fax
86-21-50328109
Email
3bsc@sina.com
Country
China
ProdList
15839
Advantage
69
Shanghai Hanhong Scientific Co.,Ltd.
Tel
021-54306202 13764082696
Email
info@hanhongsci.com
Country
China
ProdList
42958
Advantage
64
Chemsky (shanghai) International Co.,Ltd
Tel
021-50135380
Email
shchemsky@sina.com
Country
China
ProdList
15402
Advantage
60
9ding chemical ( Shanghai) Limited
Tel
4009209199
Fax
86-021-52271987
Email
sales@9dingchem.com
Country
China
ProdList
18209
Advantage
56
Guangzhou Isun Pharmaceutical Co., Ltd
Tel
020-39119399 18927568969
Fax
020-39119999
Email
isunpharm@qq.com
Country
China
ProdList
4428
Advantage
55
Jiangsu Aikon Biopharmaceutical R&D co.,Ltd.
Tel
025-66113011 18112977050
Email
cb6@aikonchem.com
Country
China
ProdList
16684
Advantage
50
Sigma-Aldrich
Tel
021-61415566 800-8193336
Email
orderCN@merckgroup.com
Country
China
ProdList
51456
Advantage
80
BOC Sciences
Tel
16314854226
Email
info@bocsci.com
Country
United States
ProdList
9923
Advantage
65
Shanghai GL Peptide Ltd.
Tel
+86-21-61263340; 17609490614 13764994101
Fax
021-61263399
Email
fisherwang@glschina.com
Country
China
ProdList
8465
Advantage
55
Changzhou Hopschain Chemical Co.,Ltd.
Tel
0519-85528066 13775048983
Fax
0519-85528066
Email
sales@hopschem.com
Country
China
ProdList
31553
Advantage
55

6232-19-5, BETA-CYANO-L-ALANINERelated Search:


  • H-ALA(3-CN)-OH
  • H-ALA(BETA-CN)-OH
  • H-BETA-CYANO-ALA-OH
  • H-BETA-CYANO-L-ALA-OH
  • BETA-CYANO-ALANINE
  • BETA-CYANO-L-ALANINE
  • 3-CYANO-L-ALANINE
  • B-cyano-L-alanine
  • H-CPA-OH
  • (2S)-2-amino-3-cyanopropanoic acid
  • (S)-2-Amino-3-cyanopropanoic acid
  • H-b-Cyano-Ala-OH
  • [S,(-)]-3-Cyano-2-aminopropionic acid
  • L-CNAla
  • H-β-Cyano-Ala-OH
  • β-Cyano-L-alanine≥ 98% (TLC)
  • β-Cyano-L-Ala-OH
  • L-Alanine, 3-cyano-
  • β-cyano-L-Alanine
  • H-β-Cyano-Ala-OH
  • inhibit,β cyano L Alanine,βcyanoLAlanine,Endogenous Metabolite,Inhibitor
  • 6232-19-5
  • Biochemicals and Reagents
  • A - H
  • Amino Acids and Peptides
  • BioChemical
  • Modified Amino Acids
  • A - H
  • Amino Acids
  • Modified Amino Acids