niga-ichigoside F1
- Product Name
- niga-ichigoside F1
- CAS No.
- 95262-48-9
- Chemical Name
- niga-ichigoside F1
- Synonyms
- DotoriosideII;niga-ichigoside F1;Urs-12-en-28-oic acid, 2,3,19,23-tetrahydroxy-, β-D-glucopyranosyl ester, (2α,3β,4α)-
- CBNumber
- CB31363365
- Molecular Formula
- C36H58O11
- Formula Weight
- 666.843
- MOL File
- 95262-48-9.mol
niga-ichigoside F1 Property
- Melting point:
- 232-234 °C
- Boiling point:
- 775.0±60.0 °C(Predicted)
- Density
- 1.35±0.1 g/cm3(Predicted)
- pka
- 12.52±0.70(Predicted)
- form
- Solid
- color
- White to off-white
N-Bromosuccinimide Price
- Product number
- SHG0005806
- Product name
- NIGA-ICHIGOSIDE F1
- Purity
- 95.00%
- Packaging
- 5MG
- Price
- $495.69
- Updated
- 2021/12/16
- Product number
- 4348
- Product name
- Niga-ichigoside F1
- Packaging
- 1mg
- Price
- $119
- Updated
- 2021/12/16
- Product number
- CFN91060
- Product name
- Niga-ichigosideF1
- Packaging
- 10mg
- Price
- $318
- Updated
- 2021/12/16
- Product number
- 4348
- Product name
- Niga-ichigoside F1
- Packaging
- 5mg
- Price
- $390
- Updated
- 2021/12/16
- Product number
- 4348
- Product name
- Niga-ichigoside F1
- Packaging
- 20mg
- Price
- $890
- Updated
- 2021/12/16
niga-ichigoside F1 Chemical Properties,Usage,Production
Uses
Niga-ichigoside F1, an orally active ursane triterpenoid, has antihyperlipidemic and antioxidant activities. Niga-ichigoside F1 can prevent high-fat diet (HFD)-induced hepatic steatosis[1].
Definition
ChEBI: 19alpha-hydroxyasiatic acid-28-O-beta-D-glucopyrannoside is a triterpenoid saponin that is 19alpha-hydroxyasiatic acid attached to a beta-D-glucopyranosyl residue at position 28 via a glycosidic linkage. It has been isolated from the leaves of Rosa laevigata. It has a role as a plant metabolite. It is a triterpenoid saponin, a pentacyclic triterpenoid, a monosaccharide derivative, a beta-D-glucoside and a tetrol. It is functionally related to a 19alpha-hydroxyasiatic acid. It derives from a hydride of an ursane.
in vivo
Niga-ichigoside F1 (40 mg/kg; oral gavage; for 12 weeks) alleviates hepatic steatosis, possibly by significantly interacting with high-fat diet (HFD) to regulate lipid metabolism genes (including Srebp1c, Acc1, Fasn, Scd1, Cpt1a and Fabp5) in four-week-old male C57BL/6J mice[1].
References
[1] Shu-Fang Xia, et al. Niga-ichigoside F1 ameliorates high-fat diet-induced hepatic steatosis in male mice by Nrf2 activation. Food Funct. 2018 Feb 21;9(2):906-916. DOI:10.1039/c7fo01051f
niga-ichigoside F1 Preparation Products And Raw materials
Raw materials
Preparation Products
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