ChemicalBook > CAS DataBase List > niga-ichigoside F1

niga-ichigoside F1

Product Name
niga-ichigoside F1
CAS No.
95262-48-9
Chemical Name
niga-ichigoside F1
Synonyms
DotoriosideII;niga-ichigoside F1;Urs-12-en-28-oic acid, 2,3,19,23-tetrahydroxy-, β-D-glucopyranosyl ester, (2α,3β,4α)-
CBNumber
CB31363365
Molecular Formula
C36H58O11
Formula Weight
666.843
MOL File
95262-48-9.mol
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niga-ichigoside F1 Property

Melting point:
232-234 °C
Boiling point:
775.0±60.0 °C(Predicted)
Density 
1.35±0.1 g/cm3(Predicted)
pka
12.52±0.70(Predicted)
form 
Solid
color 
White to off-white
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

American Custom Chemicals Corporation
Product number
SHG0005806
Product name
NIGA-ICHIGOSIDE F1
Purity
95.00%
Packaging
5MG
Price
$495.69
Updated
2021/12/16
AvaChem
Product number
4348
Product name
Niga-ichigoside F1
Packaging
20mg
Price
$890
Updated
2021/12/16
AvaChem
Product number
4348
Product name
Niga-ichigoside F1
Packaging
1mg
Price
$119
Updated
2021/12/16
Arctom
Product number
CFN91060
Product name
Niga-ichigosideF1
Packaging
10mg
Price
$318
Updated
2021/12/16
AvaChem
Product number
4348
Product name
Niga-ichigoside F1
Packaging
5mg
Price
$390
Updated
2021/12/16
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niga-ichigoside F1 Chemical Properties,Usage,Production

Uses

Niga-ichigoside F1, an orally active ursane triterpenoid, has antihyperlipidemic and antioxidant activities. Niga-ichigoside F1 can prevent high-fat diet (HFD)-induced hepatic steatosis[1].

Definition

ChEBI: 19alpha-hydroxyasiatic acid-28-O-beta-D-glucopyrannoside is a triterpenoid saponin that is 19alpha-hydroxyasiatic acid attached to a beta-D-glucopyranosyl residue at position 28 via a glycosidic linkage. It has been isolated from the leaves of Rosa laevigata. It has a role as a plant metabolite. It is a triterpenoid saponin, a pentacyclic triterpenoid, a monosaccharide derivative, a beta-D-glucoside and a tetrol. It is functionally related to a 19alpha-hydroxyasiatic acid. It derives from a hydride of an ursane.

in vivo

Niga-ichigoside F1 (40 mg/kg; oral gavage; for 12 weeks) alleviates hepatic steatosis, possibly by significantly interacting with high-fat diet (HFD) to regulate lipid metabolism genes (including Srebp1c, Acc1, Fasn, Scd1, Cpt1a and Fabp5) in four-week-old male C57BL/6J mice[1].

References

[1] Shu-Fang Xia, et al. Niga-ichigoside F1 ameliorates high-fat diet-induced hepatic steatosis in male mice by Nrf2 activation. Food Funct. 2018 Feb 21;9(2):906-916. DOI:10.1039/c7fo01051f

niga-ichigoside F1 Preparation Products And Raw materials

Raw materials

Preparation Products

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