4-[4-[2-(4-hydroxy-3,5-ditert-butyl-phenyl)sulfanylpropan-2-ylsulfanyl]-2,6-ditert-butyl-phenoxy]-4-oxo-butanoic acid Property

Melting point:

139 - 142°C

Boiling point:

659.5±55.0 °C(Predicted)

Density 

1.13±0.1 g/cm3(Predicted)

storage temp. 

2-8°C

solubility 

Chloroform (Slightly), Methanol (Slightly)

pka

4.27±0.17(Predicted)

form 

Solid

color 

White to Light Yellow

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

4-[4-[2-(4-hydroxy-3,5-ditert-butyl-phenyl)sulfanylpropan-2-ylsulfanyl]-2,6-ditert-butyl-phenoxy]-4-oxo-butanoic acid Chemical Properties,Usage,Production

Uses

An antioxidant and anti-inflammatory.

Definition

ChEBI: Succinobucol is a benzoate ester and a member of phenols.

Biological Activity

Succinobucol is a metabolically stable derivative of the antioxidant drug probucol th at poses a distinct pharmacological from. Succinobucol is an orally active vascular protectant th at exhibits antiatherosclerotic properties in multiple animal models and in humans. It inhibits the release of proinflammatory cytokines, TNF-a, IL-1b, and IL-6 in hPBMC activated by LPS.