Ammothamnine

Product Name: Ammothamnine
CAS No.: 16837-52-8
Chemical Name: Ammothamnine
Synonyms: OXYMATRINE;Kurainone;cis-matrine;ammothamnine;MATRINE OXIDE;OXYMATRINE(P);Oxymatrine,(S);Pachycarpidine;Oxymatrine CRS;matrine,1-oxide
CBNumber: CB3150469
Molecular Formula: C15H24N2O2
Formula Weight: 264.36
MOL File: 16837-52-8.mol

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Ammothamnine Property

Melting point:: 208℃
storage temp.: Inert atmosphere,2-8°C
solubility: methanol: soluble10mg/mL, clear, colorless
pka: 4.87±0.20(Predicted)
form: powder
color: white to off-white
Stability:: Hygroscopic
InChIKey: XVPBINOPNYFXID-LHDUFFHYSA-N

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Safety

Hazard Codes: Xn
Risk Statements: 22-20/22
Safety Statements: 24/25
WGK Germany: 3
RTECS: OQ1770000
HS Code: 29399990
Hazardous Substances Data: 16837-52-8(Hazardous Substances Data)

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

Precautionary statements

P270Do not eat, drink or smoke when using this product.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P330Rinse mouth.

P403Store in a well-ventilated place.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: Y0002015
Product name: Oxymatrine
Purity: European Pharmacopoeia (EP) Reference Standard
Packaging: Y0002015
Price: $150
Updated: 2023/06/20

Sigma-Aldrich

Product number: PHL89748
Product name: Oxymatrine
Purity: phyproof? Reference Substance
Packaging: 25MG
Price: $272
Updated: 2023/06/20

Alfa Aesar

Product number: H37340
Product name: Oxymatrine
Purity: 98%
Packaging: 250mg
Price: $129.65
Updated: 2024/03/01

Alfa Aesar

Product number: H37340
Product name: Oxymatrine
Purity: 98%
Packaging: 1g
Price: $369.65
Updated: 2024/03/01

Cayman Chemical

Product number: 14915
Product name: Oxymatrine
Purity: ≥98%
Packaging: 50mg
Price: $49
Updated: 2024/03/01

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Ammothamnine Chemical Properties,Usage,Production

Description

An alkaloid from Sophora angustifolia var. flavescens S. and Z., the bas'e crystal_x0002_lizes as the monohydrate having the lower melting point given above. It is dextrorotatory with [α]¹⁹_D + 47.7° (EtOH) and yields crystalline salts and derivatives: hydrobromide, m.p. 21SoC; aurichloride, m.p. 207°C (dec.); perchlorate, m.p. 240°C (dec.); picrate, m.p. 21SoC and the methochloride aurichloride, m.p. 18SoC (dec.). Ochiai and Ito have shown that it is formed by the action of hydrogen peroxide on Matrine (q.v.), indicating that its structure is matrine-N-oxide.

Description

Oxymatrine is a natural alkaloid isolated from the root of S. flavescens, an herb used in traditional Chinese herbal medicine. It has antiviral properties, inhibiting the replication of hepatitis B alone and in combination with lamivudine. Oxymatrine also prevents fibrosis in a number of organs including liver, at least in part by interfering with TGF-β signaling. This compound also induces apoptosis in certain cancer cells and ameliorates inflammation by impairing the translocation of nuclear factors-κB.

Uses

Oxymatrine is a an anti-tumor agent triggering apoptosis in human leukemia cells.

Uses

antifungal, hepatoprotectant

Definition

ChEBI: Ammothamnine is an alkaloid and a tertiary amine oxide.

References

Kondo et al., Arch. Pharm., 275,493 (1937)
Ochiai, Ito., Ber., 81,938 (1938)

Ammothamnine Preparation Products And Raw materials

Raw materials

Preparation Products

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Ammothamnine Suppliers

China 416 Europe 2 Germany 1 India 3 Japan 1 South Korea 2 United Kingdom 9 United States 35 Global 470

Nanjing Duolong Bio-tech Co.,Ltd.

Tel: 18905173768
Fax: 025-83263139
Email: sales@dolonchem.com
Country: China
ProdList: 2297
Advantage: 50

Shaanxi Pioneer Biotech Co., Ltd.

Tel: 13720616393；029-84385017-8003 13720616393
Fax: 029-84385017
Email: sales@pioneerbiotech.com
Country: China
ProdList: 1065
Advantage: 56

Shanghai Boyle Chemical Co., Ltd.

Tel: 021-50182298 021-50180596
Fax: +86-21-57758967
Email: sales@boylechem.com
Country: China
ProdList: 2210
Advantage: 55

3B Pharmachem (Wuhan) International Co.,Ltd.

Tel: 821-50328103-801 18930552037
Fax: 86-21-50328109
Email: 3bsc@sina.com
Country: China
ProdList: 15848
Advantage: 69

Chembest Research Laboratories Limited

Tel: 021-20908456
Fax: 021-58180499
Email: sales@BioChemBest.com
Country: China
ProdList: 6011
Advantage: 61

BeiJing Hwrk Chemicals Limted

Tel: 0757-86329057 18501085097
Fax: 010-89508210
Email: sales3.gd@hwrkchemical.com
Country: China
ProdList: 7583
Advantage: 55

Energy Chemical

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Email: sales8178@energy-chemical.com
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Beijing Ouhe Technology Co., Ltd

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Adamas Reagent, Ltd.

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Country: China
ProdList: 14113
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Shanghai Hanhong Scientific Co.,Ltd.

Tel: 021-54306202 13764082696;
Email: info@hanhongsci.com
Country: China
ProdList: 42982
Advantage: 64

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View Lastest Price from Ammothamnine manufacturers

Shaanxi Haibo Biotechnology Co., Ltd

Product: Ammothamnine 16837-52-8
Price: US $0.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 2000ton
Release date: 2023-12-05

Wuhan Boyuan Import & Export Co., LTD

Product: (1R,2R,9S,13S,17S)-13-Oxido-7-aza-13-azoniatetracyclo[7.7.1.02,7.013,17]heptadecan-6-one 16837-52-8
Price: US $18.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 5000tons
Release date: 2024-04-07

Hebei Duling International Trade Co. LTD

Product: Ammothamnine 16837-52-8
Price: US $50.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 1
Release date: 2022-10-18

16837-52-8, AmmothamnineRelated Search:

Iron oxide NITRIC OXIDE Zinc oxide Magnesium oxide SophoraAlkaloidsTannate Propylene oxide Matrine ETHYLENE OXIDE 13,14-Didehydromatridin-15-one Oxyresveratrol oxypaeoniflora OXYPEUCEDANIN Oxyepiberberine oxysophoridine OXYSOPHOCARPINE (Diethoxymethyl)diphenylphosphine oxide Rotundine Quercetin dihydrate

OXYMATRINE

1-oxide,(1-beta)-matridin-15-on

1H,5H,10H-Dipyrido[2,1-f:3',2',1'-ij][1,6]naphthyridin-10-one, dodecahydro-, 4-oxide, (4R,7aS,13aR,13bR,13cS)-

Ammothamnine Oxymatrine

Oxymatrine, 98%, from Sophora flavescens Aiton

(4R,7aS,13aR,13bR,13cS)-dodecahydro-4-oxide-1H,5H,10H-dipyrido[2,1-f:3',2',1'-ij][1,6]naphthyridin-10-one

Oxymatrine 16837-52-8

matrine,1-oxide

matrine1beta-oxide

ammothamnine

(6AS,11AR,11BR,11CS)-3A-OXY-DODECAHYDRO-3A,7A-DIAZA-BENZO[DE]ANTHRACEN-8-ONE

matrine n-oxide

MATRINE OXIDE

Kurainone

OXYMATRINE, 98.0% BY HPLC

Oxymatrine std.

OXYMATRINE(P)

Matridin-15-one,1-oxide, (1β)-

Oxymatrine，Matrine N-oxide，Ammothamnine

Matrine N-oxide. Ammothamnine. Pachycarpidine

Oxymatrine,(S)

Dodecahydro-1,8-dihydroxy-7,14-methano-4H,6H-dipyrido[1,2-a:1',2'-e][1,5]diazocin-4-one

OxyMatrine(Matrine N-oxide)

Pachycarpidine

cis-matrine

Oxymatrine CRS

Oxymatrine Standard

Ammothamnine USP/EP/BP

(1R,2R,9S,13S,17S)-13-Oxido-7-aza-13-azoniatetracyclo[7.7.1.02,7.013,17]heptadecan-6-one

(4S,41S,7aS,13aR,13bR)-10-Oxododecahydro-1H,5H-dipyrido[2,1-f:3',2',1'-ij][1,6]naphthyridine 4(41H)-oxide

oxymatrine?pesticide

Oxymatrine Marine

16837-52-8

6837-52-8

C15H24N2O2

Pyrazoles

Inhibitors

reference standards from Chinese medicinal herbs (TCM).

standardized herbal extract

Plant extracts

chemical reagent

pharmaceutical intermediate

phytochemical

Plant extract

Alkaloids

Natural Plant Extract

Pharmaceutical material and intermeidates

16837-52-8