ChemicalBook > CAS DataBase List > Sophocarpine Monohydrate

Sophocarpine Monohydrate

Product Name
Sophocarpine Monohydrate
CAS No.
145572-44-7
Chemical Name
Sophocarpine Monohydrate
Synonyms
SOPHOCARPINE;Sophocarpinpe;Sophora alkaloids;Matridine-13-ene-15-one;sophocarpine 145572-44-7;Sophocarpine Monohydrate;13,14-didehydromatridin-15-one;Sophocarpine monohydrate, 10 mM in DMSO;13,14-Didehydromatridin-15-one USP/EP/BP;Matridin-15-one, 13,14-didehydro-, monohydrate (9CI)
CBNumber
CB7170221
Molecular Formula
C15H22N2O
Formula Weight
246.35
MOL File
145572-44-7.mol
More
Less

Sophocarpine Monohydrate Property

Melting point:
8l-2°C
storage temp. 
-20°C Freezer
solubility 
Acetone; Dichloromethane
form 
Solid
color 
Pale brownish
More
Less

Safety

HS Code 
2939.80.0000
More
Less

Hazard and Precautionary Statements (GHS)

More
Less

N-Bromosuccinimide Price

TCI Chemical
Product number
O0505
Product name
Sophocarpine Monohydrate
Purity
>98.0%(HPLC)
Packaging
25mg
Price
$24
Updated
2025/07/31
TCI Chemical
Product number
O0505
Product name
Sophocarpine Monohydrate
Purity
>98.0%(HPLC)
Packaging
100mg
Price
$62
Updated
2025/07/31
TRC
Product number
S676825
Product name
Sophocarpine Monohydrate
Packaging
10mg
Price
$120
Updated
2021/12/16
Usbiological
Product number
300995
Product name
Sophocarpine
Packaging
20mg
Price
$405
Updated
2021/12/16
ChemScene
Product number
CS-0008947
Product name
Sophocarpine Monohydrate
Purity
>99.0%
Packaging
5mg
Price
$50
Updated
2021/12/16
More
Less

Sophocarpine Monohydrate Chemical Properties,Usage,Production

Description

A tetracyclic alkaloid present in Sophora species, this base crystallizes from H20 as the monohydrate, m.p. 54-5°C which becomes anhydrous in vacuo. It has [α]18D - 29.44° (EtOH) and yields the following salts: hydrochloride, m.p. > 300°C; hydriodide, m.p. 277-9°C; aurichloride, m.p. l66-7°C; platinichloride, m.p. 207-212°C (dec.); picrate, m.p. ISS-7°C and the methiodide, m.p. 200-2°C. Reduction of the base by electrolysis yields a crystalline, volatile base, ClsH26N2, b.p. l53-4°C/5 mm; [α]D - 26.2° (EtOH) and giving a methiodide with a melting point above 300°C. Attempted degradation by the Hofmann process has proved unsuccessful.

Chemical Properties

White needle-shaped crystals, soluble in organic solvents such as methanol, ethanol, DMSO, etc., derived from Sophora flavescens, a plant of the genus Macleaya in the Papaveraceae family.

Uses

Sophocarpine Monohydrate alleviates non-alcoholic steatohepatitis, which is a resultant effect of non-alcoholic fatty lifer disease. Admission of this compound results in a decrease in liver weight and serum lipids. Antiviral agent, Sophocarpine also displays a profound effect against coxsackievirus and therapeutical effects of viral myocarditis.

IC 50

PI3K

References

Orekhov, Proskurnina., Ber., 67,77 (1934)
Proskurnina, Kuzuvkov., Dokl. Akad. Nauk SSSR, 91, 1145 (1953)
Okuda et al., Chern. & Ind., 1326 (1962)

Sophocarpine Monohydrate Preparation Products And Raw materials

Raw materials

Preparation Products

More
Less

Sophocarpine Monohydrate Suppliers

Adamas Reagent, Ltd.
Tel
400-6009262 16621234537
Fax
021-64823266
Email
chenyj@titansci.com
Country
China
ProdList
14101
Advantage
59
Shandong Xiya Chemical Co., Ltd
Tel
4009903999 13355009207
Fax
0539-6365991
Email
3007715519@qq.com
Country
China
ProdList
18729
Advantage
57
Sichuan Kulinan Technology Co., Ltd
Tel
400-1166-196 18981987031
Fax
028-84555506 800101999
Email
cdhxsj@163.com
Country
China
ProdList
11705
Advantage
57
Shenzhen Sungening Bio-Tech Co., Ltd
Tel
+86-0755-89668383
Fax
+86-0755-89594066/4038
Email
sales@sungening.com
Country
China
ProdList
1319
Advantage
65
Dalian Meilun Biotech Co., Ltd.
Tel
0411-62910999 13889544652
Email
sales@meilune.com
Country
China
ProdList
4747
Advantage
58
ShangHai YuanYe Biotechnology Co., Ltd.
Tel
021-61312847 13636370518
Fax
021-55068248
Email
shyysw007@163.com
Country
China
ProdList
4999
Advantage
60
Chengdu Ai Keda Chemical Technology Co., Ltd.
Tel
4008-755-333 18080918076
Fax
028-86757656
Email
800078821@qq.com
Country
China
ProdList
9718
Advantage
55
Chengdu Climax Biotech Co., Ltd.
Tel
028-83311324 1278112614
Fax
028-83311324
Email
climaxbiotech@gmail.com
Country
China
ProdList
925
Advantage
58
Nanjing Spring & Autumn Biological Engineering Co., Ltd.
Tel
025-84430028 13815430202
Email
sale02@cqherb.com
Country
China
ProdList
294
Advantage
59
Beijing HuaMeiHuLiBiological Chemical
Tel
010-56205725
Fax
010-65763397
Email
waley188@sohu.com
Country
China
ProdList
12335
Advantage
58
More
Less

View Lastest Price from Sophocarpine Monohydrate manufacturers

NanJing Spring & Autumn Biological Engineering CO., LTD.
Product
sophocarpine 145572-44-7 145572-44-7
Price
US $12.50/mg
Min. Order
20mg
Purity
≥98%
Supply Ability
1000.00 kgs
Release date
2019-07-11
Career Henan Chemical Co
Product
Sophocarpine 145572-44-7
Price
US $1.00/KG
Min. Order
1KG
Purity
98%
Supply Ability
200KG
Release date
2020-01-09

145572-44-7, Sophocarpine MonohydrateRelated Search:


  • SOPHOCARPINE
  • 13,14-didehydromatridin-15-one
  • (6AS,11AR,11BR,11CS)-2,3,5,6,6A,7,11,11A,11B,11C-DECAHYDRO-1H,4H-3A,7A-DIAZA-BENZO[DE]ANTHRACEN-8-ONE
  • Matridine-13-ene-15-one
  • (41S,7aS,13aR,13bR)-2,3,41,6,7,7a,8,13,13a,13b-Decahydro-1H,5H,10H-dipyrido[2,1-f:3',2',1'-ij][1,6]naphthyridin-10-one hydrate
  • Sophocarpine Monohydrate
  • Sophocarpinpe
  • Sophora alkaloids
  • sophocarpine 145572-44-7
  • 13,14-Didehydromatridin-15-one USP/EP/BP
  • Matridin-15-one, 13,14-didehydro-, monohydrate (9CI)
  • Sophocarpine monohydrate, 10 mM in DMSO
  • 145572-44-7
  • Inhibitors
  • chemical reagent
  • pharmaceutical intermediate
  • phytochemical
  • reference standards from Chinese medicinal herbs (TCM).
  • standardized herbal extract