ChemicalBook > CAS DataBase List > Sophocarpine Monohydrate

Sophocarpine Monohydrate

Product Name
Sophocarpine Monohydrate
CAS No.
145572-44-7
Chemical Name
Sophocarpine Monohydrate
Synonyms
SOPHOCARPINE;Sophocarpinpe;Sophora alkaloids;Matridine-13-ene-15-one;sophocarpine 145572-44-7;Sophocarpine Monohydrate;13,14-didehydromatridin-15-one;Sophocarpine monohydrate, 10 mM in DMSO;13,14-Didehydromatridin-15-one USP/EP/BP;Matridin-15-one, 13,14-didehydro-, monohydrate (9CI)
CBNumber
CB7170221
Molecular Formula
C15H22N2O
Formula Weight
246.35
MOL File
145572-44-7.mol
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Sophocarpine Monohydrate Property

Melting point:
8l-2°C
storage temp. 
-20°C Freezer
solubility 
Acetone; Dichloromethane
form 
Solid
color 
Pale brownish
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Safety

HS Code 
2939.80.0000
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

TCI Chemical
Product number
O0505
Product name
Sophocarpine Monohydrate
Purity
>98.0%(HPLC)
Packaging
25mg
Price
$24
Updated
2025/07/31
TCI Chemical
Product number
O0505
Product name
Sophocarpine Monohydrate
Purity
>98.0%(HPLC)
Packaging
100mg
Price
$62
Updated
2025/07/31
TRC
Product number
S676825
Product name
Sophocarpine Monohydrate
Packaging
10mg
Price
$120
Updated
2021/12/16
Usbiological
Product number
300995
Product name
Sophocarpine
Packaging
20mg
Price
$405
Updated
2021/12/16
ChemScene
Product number
CS-0008947
Product name
Sophocarpine Monohydrate
Purity
>99.0%
Packaging
5mg
Price
$50
Updated
2021/12/16
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Sophocarpine Monohydrate Chemical Properties,Usage,Production

Description

A tetracyclic alkaloid present in Sophora species, this base crystallizes from H20 as the monohydrate, m.p. 54-5°C which becomes anhydrous in vacuo. It has [α]18D - 29.44° (EtOH) and yields the following salts: hydrochloride, m.p. > 300°C; hydriodide, m.p. 277-9°C; aurichloride, m.p. l66-7°C; platinichloride, m.p. 207-212°C (dec.); picrate, m.p. ISS-7°C and the methiodide, m.p. 200-2°C. Reduction of the base by electrolysis yields a crystalline, volatile base, ClsH26N2, b.p. l53-4°C/5 mm; [α]D - 26.2° (EtOH) and giving a methiodide with a melting point above 300°C. Attempted degradation by the Hofmann process has proved unsuccessful.

Chemical Properties

White needle-shaped crystals, soluble in organic solvents such as methanol, ethanol, DMSO, etc., derived from Sophora flavescens, a plant of the genus Macleaya in the Papaveraceae family.

Uses

Sophocarpine Monohydrate alleviates non-alcoholic steatohepatitis, which is a resultant effect of non-alcoholic fatty lifer disease. Admission of this compound results in a decrease in liver weight and serum lipids. Antiviral agent, Sophocarpine also displays a profound effect against coxsackievirus and therapeutical effects of viral myocarditis.

IC 50

PI3K

References

Orekhov, Proskurnina., Ber., 67,77 (1934)
Proskurnina, Kuzuvkov., Dokl. Akad. Nauk SSSR, 91, 1145 (1953)
Okuda et al., Chern. & Ind., 1326 (1962)

Sophocarpine Monohydrate Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from Sophocarpine Monohydrate manufacturers

NanJing Spring & Autumn Biological Engineering CO., LTD.
Product
sophocarpine 145572-44-7 145572-44-7
Price
US $12.50/mg
Min. Order
20mg
Purity
≥98%
Supply Ability
1000.00 kgs
Release date
2019-07-11
Career Henan Chemical Co
Product
Sophocarpine 145572-44-7
Price
US $1.00/KG
Min. Order
1KG
Purity
98%
Supply Ability
200KG
Release date
2020-01-09

145572-44-7, Sophocarpine MonohydrateRelated Search:


  • SOPHOCARPINE
  • 13,14-didehydromatridin-15-one
  • (6AS,11AR,11BR,11CS)-2,3,5,6,6A,7,11,11A,11B,11C-DECAHYDRO-1H,4H-3A,7A-DIAZA-BENZO[DE]ANTHRACEN-8-ONE
  • Matridine-13-ene-15-one
  • (41S,7aS,13aR,13bR)-2,3,41,6,7,7a,8,13,13a,13b-Decahydro-1H,5H,10H-dipyrido[2,1-f:3',2',1'-ij][1,6]naphthyridin-10-one hydrate
  • Sophocarpine Monohydrate
  • Sophocarpinpe
  • Sophora alkaloids
  • sophocarpine 145572-44-7
  • 13,14-Didehydromatridin-15-one USP/EP/BP
  • Matridin-15-one, 13,14-didehydro-, monohydrate (9CI)
  • Sophocarpine monohydrate, 10 mM in DMSO
  • 145572-44-7
  • Inhibitors
  • chemical reagent
  • pharmaceutical intermediate
  • phytochemical
  • reference standards from Chinese medicinal herbs (TCM).
  • standardized herbal extract