ChemicalBook > CAS DataBase List > 13,14-Didehydromatridin-15-one

13,14-Didehydromatridin-15-one

Product Name
13,14-Didehydromatridin-15-one
CAS No.
145572-44-7
Chemical Name
13,14-Didehydromatridin-15-one
Synonyms
SOPHOCARPINE;Sophocarpinpe;Sophora alkaloids;Matridine-13-ene-15-one;sophocarpine 145572-44-7;Sophocarpine Monohydrate;13,14-didehydromatridin-15-one;13,14-Didehydromatridin-15-one USP/EP/BP;Matridin-15-one, 13,14-didehydro-, monohydrate (9CI);(6AS,11AR,11BR,11CS)-2,3,5,6,6A,7,11,11A,11B,11C-DECAHYDRO-1H,4H-3A,7A-DIAZA-BENZO[DE]ANTHRACEN-8-ONE
CBNumber
CB7170221
Molecular Formula
C15H22N2O
Formula Weight
246.35
MOL File
145572-44-7.mol
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13,14-Didehydromatridin-15-one Property

Melting point:
8l-2°C
storage temp. 
-20°C Freezer
solubility 
Acetone; Dichloromethane
form 
Solid
color 
Pale brownish
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Safety

HS Code 
2939.80.0000
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

TCI Chemical
Product number
O0505
Product name
Sophocarpine Monohydrate
Purity
>98.0%(HPLC)
Packaging
25mg
Price
$25
Updated
2024/03/01
TCI Chemical
Product number
O0505
Product name
Sophocarpine Monohydrate
Purity
>98.0%(HPLC)
Packaging
100mg
Price
$65
Updated
2024/03/01
TRC
Product number
S676825
Product name
Sophocarpine Monohydrate
Packaging
10mg
Price
$120
Updated
2021/12/16
Usbiological
Product number
300995
Product name
Sophocarpine
Packaging
20mg
Price
$405
Updated
2021/12/16
ChemScene
Product number
CS-0008947
Product name
Sophocarpine Monohydrate
Purity
>99.0%
Packaging
5mg
Price
$50
Updated
2021/12/16
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13,14-Didehydromatridin-15-one Chemical Properties,Usage,Production

Description

A tetracyclic alkaloid present in Sophora species, this base crystallizes from H20 as the monohydrate, m.p. 54-5°C which becomes anhydrous in vacuo. It has [α]18D - 29.44° (EtOH) and yields the following salts: hydrochloride, m.p. > 300°C; hydriodide, m.p. 277-9°C; aurichloride, m.p. l66-7°C; platinichloride, m.p. 207-212°C (dec.); picrate, m.p. ISS-7°C and the methiodide, m.p. 200-2°C. Reduction of the base by electrolysis yields a crystalline, volatile base, ClsH26N2, b.p. l53-4°C/5 mm; [α]D - 26.2° (EtOH) and giving a methiodide with a melting point above 300°C. Attempted degradation by the Hofmann process has proved unsuccessful.

Uses

Sophocarpine Monohydrate alleviates non-alcoholic steatohepatitis, which is a resultant effect of non-alcoholic fatty lifer disease. Admission of this compound results in a decrease in liver weight and serum lipids. Antiviral agent, Sophocarpine also displays a profound effect against coxsackievirus and therapeutical effects of viral myocarditis.

References

Orekhov, Proskurnina., Ber., 67,77 (1934)
Proskurnina, Kuzuvkov., Dokl. Akad. Nauk SSSR, 91, 1145 (1953)
Okuda et al., Chern. & Ind., 1326 (1962)

13,14-Didehydromatridin-15-one Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from 13,14-Didehydromatridin-15-one manufacturers

NanJing Spring & Autumn Biological Engineering CO., LTD.
Product
sophocarpine 145572-44-7 145572-44-7
Price
US $12.50/mg
Min. Order
20mg
Purity
≥98%
Supply Ability
1000.00 kgs
Release date
2019-07-11
Career Henan Chemical Co
Product
Sophocarpine 145572-44-7
Price
US $1.00/KG
Min. Order
1KG
Purity
98%
Supply Ability
200KG
Release date
2020-01-09

145572-44-7, 13,14-Didehydromatridin-15-oneRelated Search:


  • SOPHOCARPINE
  • 13,14-didehydromatridin-15-one
  • (6AS,11AR,11BR,11CS)-2,3,5,6,6A,7,11,11A,11B,11C-DECAHYDRO-1H,4H-3A,7A-DIAZA-BENZO[DE]ANTHRACEN-8-ONE
  • Matridine-13-ene-15-one
  • (41S,7aS,13aR,13bR)-2,3,41,6,7,7a,8,13,13a,13b-Decahydro-1H,5H,10H-dipyrido[2,1-f:3',2',1'-ij][1,6]naphthyridin-10-one hydrate
  • Sophocarpine Monohydrate
  • Sophocarpinpe
  • Sophora alkaloids
  • sophocarpine 145572-44-7
  • 13,14-Didehydromatridin-15-one USP/EP/BP
  • Matridin-15-one, 13,14-didehydro-, monohydrate (9CI)
  • 145572-44-7
  • Inhibitors
  • chemical reagent
  • pharmaceutical intermediate
  • phytochemical
  • reference standards from Chinese medicinal herbs (TCM).
  • standardized herbal extract