ChemicalBook > CAS DataBase List > 4-METHYL-1H-IMIDAZOLE-2-CARBOXYLICACID

4-METHYL-1H-IMIDAZOLE-2-CARBOXYLICACID

Product Name: 4-METHYL-1H-IMIDAZOLE-2-CARBOXYLICACID
CAS No.: 70631-93-5
Chemical Name: 4-METHYL-1H-IMIDAZOLE-2-CARBOXYLICACID
Synonyms: 5-Methyl-1H-iMidazole-2-carboxylic acid;Imidazole-2-carboxylic acid, 4-methyl-;4-Methylimidazole-2-carboxylic Acid;4-METHYL-1H-IMIDAZOLE-2-CARBOXYLICACID;4-methyl-3H-imidazole-2-carboxylic acid;1H-Imidazole-2-carboxylic acid, 5-methyl-;4-methyl-1H-imidazole-2-carboxylic acid(SALTDATA: 1.2H2O 0.08NaCl)
CBNumber: CB31511652
Molecular Formula: C5H6N2O2
Formula Weight: 126.11
MOL File: 70631-93-5.mol

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4-METHYL-1H-IMIDAZOLE-2-CARBOXYLICACID Property

storage temp.: 2-8°C
Appearance: Off-white to light brown Solid
InChI: InChI=1S/C5H6N2O2/c1-3-2-6-4(7-3)5(8)9/h2H,1H3,(H,6,7)(H,8,9)
InChIKey: JYKNMRPMJXDBJS-UHFFFAOYSA-N
SMILES: C1(C(O)=O)NC(C)=CN=1

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Safety

Hazard Codes: Xi
Risk Statements: 36
Safety Statements: 26
HazardClass: IRRITANT

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

TRC

Product number: M328088
Product name: 5-Methyl-1H-imidazole-2-carboxylicAcid
Packaging: 50mg
Price: $1200
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: CHM0162779
Product name: 4-METHYL-1H-IMIDAZOLE-2-CARBOXYLIC ACID HYDRATE
Purity: 95.00%
Packaging: 5G
Price: $1443.75
Updated: 2021/12/16

Matrix Scientific

Product number: 064442
Product name: 4-Methyl-1H-imidazole-2-carboxylic acid
Packaging: 1g
Price: $435
Updated: 2021/12/16

AK Scientific

Product number: Y9876
Product name: 4-Methyl-1H-imidazole-2-carboxylicacid
Packaging: 1g
Price: $637
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: CHM0162779
Product name: 4-METHYL-1H-IMIDAZOLE-2-CARBOXYLIC ACID HYDRATE
Purity: 95.00%
Packaging: 0.5G
Price: $726
Updated: 2021/12/16

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4-METHYL-1H-IMIDAZOLE-2-CARBOXYLICACID Chemical Properties,Usage,Production

Uses

5-Methyl-1H-imidazole-2-carboxylic acid (cas# 70631-93-5) is a useful research chemical. It is in the chemical composition of steam and solvent crude oil extracts from azadirachta indica leaves. It is also in the slurry composition for chemical mechanical polishing of metal cable.

Definition

ChEBI: 5-methyl-imidazole-2-carboxylic acid is an imidazolyl carboxylic acid that is 1H-imidazole with methyl and carboxylic acid group substituents at positions 5 and 2 respectively. It has a role as a metabolite.

Synthesis

40253-44-9

70631-93-5

General procedure for the synthesis of 4-methyl-1H-imidazole-2-carboxylic acid from ethyl 4-methyl-1H-imidazole-2-carboxylate: ethyl 4-methyl-1H-imidazole-2-carboxylate (77.0 g, 0.5 mol) was dissolved in anhydrous ethanol (600 mL) at room temperature, and 250 mL of 40% aqueous sodium hydroxide was subsequently added. The reaction mixture was heated to 50 °C and maintained at this temperature for the reaction. Upon completion of the reaction, it was cooled to room temperature, neutralized and acidified with 37% concentrated hydrochloric acid to pH=6. The solvent was removed by distillation under reduced pressure and the resulting residue was purified by column chromatography using dichloromethane/methanol (10:1, v/v) as eluent to give the final 4-methyl-1H-imidazole-2-carboxylic acid (60.2 g, 96% yield) as a white solid.

References

[1] Patent: CN104016925, 2016, B. Location in patent: Paragraph 0028-0030; 0038; 0039
[2] Journal of Heterocyclic Chemistry, 2018, vol. 55, # 11, p. 2619 - 2622

4-METHYL-1H-IMIDAZOLE-2-CARBOXYLICACID Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from 4-METHYL-1H-IMIDAZOLE-2-CARBOXYLICACID manufacturers

Career Henan Chemical Co

Product: 4-METHYL-1H-IMIDAZOLE-2-CARBOXYLICACID 70631-93-5
Price: US $7.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: JD 816
Release date: 2019-09-02

70631-93-5, 4-METHYL-1H-IMIDAZOLE-2-CARBOXYLICACIDRelated Search:

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4-METHYL-1H-IMIDAZOLE-2-CARBOXYLICACID

4-methyl-1H-imidazole-2-carboxylic acid(SALTDATA: 1.2H2O 0.08NaCl)

5-Methyl-1H-iMidazole-2-carboxylic acid

4-methyl-3H-imidazole-2-carboxylic acid

Imidazole-2-carboxylic acid, 4-methyl-

1H-Imidazole-2-carboxylic acid, 5-methyl-

4-Methylimidazole-2-carboxylic Acid

70631-93-5