(S)-2-(Aminomethyl)-1-Cbz-pyrrolidine
- Product Name
- (S)-2-(Aminomethyl)-1-Cbz-pyrrolidine
- CAS No.
- 119020-03-0
- Chemical Name
- (S)-2-(Aminomethyl)-1-Cbz-pyrrolidine
- Synonyms
- BUTTPARK 93\50-51;N-CBZ-4-AMINOMETHYLPIPERIDINE;1-CBZ-2-AMINOMETHYL PYRROLIDINE;4-AMINOMETHYL-1-N-CBZ-PIPERIDINE;2-(Aminomethyl)-1-Cbz-pyrrolidine;(S)-1-CBZ-2-AMINOMETHYLPYRROLIDINE;1-N-CBZ-2-(AMINOMETHYL)PYRROLIDINE;(S)-2-(Aminomethyl)-1-Cbz-pyrrolidine;(S)-2-AMINOMETHYL-1-N-CBZ-PYRROLIDINE;(S)-1-N-CBZ-2-(AMINOMETHYL)PYRROLIDINE
- CBNumber
- CB3151325
- Molecular Formula
- C13H18N2O2
- Formula Weight
- 234.29
- MOL File
- 119020-03-0.mol
(S)-2-(Aminomethyl)-1-Cbz-pyrrolidine Property
- Boiling point:
- 370.5±25.0 °C(Predicted)
- Density
- 1.155±0.06 g/cm3(Predicted)
- storage temp.
- Keep in dark place,Inert atmosphere,2-8°C
- pka
- 9.91±0.29(Predicted)
- Appearance
- Colorless to light yellow Liquid
- CAS DataBase Reference
- 119020-03-0(CAS DataBase Reference)
Safety
- Hazard Codes
- Xn
- Risk Statements
- 36/37/38-41-37/38-22
- Safety Statements
- 26-36/37/39-39
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- A635033
- Product name
- 2-Aminomethyl-pyrrolidine-1-carboxylicAcidBenzylEster
- Packaging
- 100mg
- Price
- $65
- Updated
- 2021/12/16
- Product number
- A635033
- Product name
- 2-Aminomethyl-pyrrolidine-1-carboxylicAcidBenzylEster
- Packaging
- 500mg
- Price
- $220
- Updated
- 2021/12/16
- Product number
- FA56379
- Product name
- 2-Aminomethyl-pyrrolidine-1-carboxylic acid benzyl ester
- Packaging
- 1g
- Price
- $230
- Updated
- 2021/12/16
- Product number
- FA56379
- Product name
- 2-Aminomethyl-pyrrolidine-1-carboxylic acid benzyl ester
- Packaging
- 2g
- Price
- $368
- Updated
- 2021/12/16
- Product number
- FA56379
- Product name
- 2-Aminomethyl-pyrrolidine-1-carboxylic acid benzyl ester
- Packaging
- 5G
- Price
- $588.8
- Updated
- 2021/12/16
(S)-2-(Aminomethyl)-1-Cbz-pyrrolidine Chemical Properties,Usage,Production
Uses
(S)-Benzyl 2-(aminomethyl)pyrrolidine-1-carboxylate was a useful reagent in preparation of trifluoro-N-[(S)-pyrrolidinylmethyl]methanesulfonamide.
Synthesis
141774-67-6
119020-03-0
GENERAL METHOD: Under stirring conditions, azide derivatives 9a or 9b (4.03 mmol) were dissolved in THF (1 mL), followed by the addition of solid triphenylphosphine (Ph3P, 4.03 mmol) and water (H2O, 6.04 mmol). The reaction mixture was stirred continuously for 12 h at room temperature. After completion of the reaction, the solvent was removed by concentration under reduced pressure. The crude product was purified by rapid column chromatography on silica gel with the eluent being a solvent mixture of methanol-dichloromethane (9:1, v/v).
References
[1] Synthetic Communications, 2011, vol. 41, # 17, p. 2517 - 2523
[2] Synthesis (Germany), 2013, vol. 45, # 17, p. 2458 - 2468
[3] Tetrahedron Letters, 2010, vol. 51, # 1, p. 209 - 212
[4] Tetrahedron Letters, 1991, vol. 32, # 49, p. 7183 - 7186
(S)-2-(Aminomethyl)-1-Cbz-pyrrolidine Preparation Products And Raw materials
Raw materials
Preparation Products
(S)-2-(Aminomethyl)-1-Cbz-pyrrolidine Suppliers
- Tel
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- Fax
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- interchim@interchim.com
- Country
- France
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- 6302
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View Lastest Price from (S)-2-(Aminomethyl)-1-Cbz-pyrrolidine manufacturers
- Product
- (S)-1-Cbz-2-aminomethylpyrrolidine 119020-03-0
- Price
- US $1.10-9.90/kg
- Min. Order
- 1kg
- Purity
- 99%min
- Supply Ability
- 100kg
- Release date
- 2025-08-18
- Product
- (S)-2-(Aminomethyl)-1-Cbz-pyrrolidine 119020-03-0
- Price
- US $1.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 200kg
- Release date
- 2019-12-24