H-SER-PHE-LEU-LEU-ARG-OH

Product Name: H-SER-PHE-LEU-LEU-ARG-OH
CAS No.: 141685-53-2
Chemical Name: H-SER-PHE-LEU-LEU-ARG-OH
Synonyms: SFLLR;SER-PHE-LEU-LEU-ARG;H-SER-PHE-LEU-LEU-ARG-OH;Thrombin Receptor Activator for Peptide 5 (TRAP-5);L-Seryl-L-phenylalanyl-L-leucyl-L-leucyl-L-arginine;L-Arginine, L-seryl-L-phenylalanyl-L-leucyl-L-leucyl-;SFLLR, Coagulation Factor II Receptor (1-5) (huMan), PAR-1 (1-5) (huMan), ThroMbin Receptor (1-5) (huMan), ThroMbin Receptor Activator Peptide 5, Proteinase Activated Receptor 1 (1-5) (huMan)
CBNumber: CB3151835
Molecular Formula: C30H50N8O7
Formula Weight: 634.77
MOL File: 141685-53-2.mol

More

Less

H-SER-PHE-LEU-LEU-ARG-OH Property

Density: 1.32±0.1 g/cm3(Predicted)
storage temp.: -15°C
solubility: insoluble in EtOH; ≥14.63 mg/mL in H2O; ≥63.5 mg/mL in DMSO
form: solid
pka: 3.34±0.10(Predicted)

More

Less

Hazard and Precautionary Statements (GHS)

More

Less

N-Bromosuccinimide Price

ApexBio Technology

Product number: A1036
Product name: ThrombinReceptorActivatorforPeptide5(TRAP-5)
Packaging: 5mg
Price: $45
Updated: 2021/12/16

ApexBio Technology

Product number: A1036
Product name: ThrombinReceptorActivatorforPeptide5(TRAP-5)
Packaging: 10mg
Price: $75
Updated: 2021/12/16

ChemScene

Product number: CS-0044800
Product name: ThrombinReceptorActivatorforPeptide5TRAP-5
Packaging: 1mg
Price: $80
Updated: 2021/12/16

ApexBio Technology

Product number: A1036
Product name: ThrombinReceptorActivatorforPeptide5(TRAP-5)
Packaging: 25mg
Price: $105
Updated: 2021/12/16

ChemScene

Product number: CS-0044800
Product name: ThrombinReceptorActivatorforPeptide5TRAP-5
Packaging: 5mg
Price: $180
Updated: 2021/12/16

More

Less

H-SER-PHE-LEU-LEU-ARG-OH Chemical Properties,Usage,Production

Biological Activity

thrombin receptor activator for peptide 5 (trap-5),(c30h50n8o7), a peptide with the sequence nh2-ser-phe-leu-leu-arg-cooh, mw= 634.76. coagulation factor ii (thrombin) receptor is a g protein-coupled receptor involved in the regulation of thrombotic response. proteolytic cleavage leads to the activation of the receptor(1). thrombin signalling in platelets contributes to hemostasis and thrombosis. endothelial pars participate in the regulation of vascular tone and permeability while in vascular smooth muscle they mediate contraction, proliferation, and hypertrophy. pars contribute to the pro-inflammatory response observed in atherosclerosis and restenosis. recent research has also implicated these novel receptors in muscle growth and bone cell differentiation and proliferation(2). in t cells, activation of par1, par2 and par3 induce tyrosine phosphorylation of vav1. activation of pars also led to an increase in tyrosine phosphorylation of zap-70 and slp-76, two key proteins in t cell receptor (tcr) signalling(3).figure1 formula of thrombin receptor activator for peptide 5 (trap-5)figure2 structure of thrombin receptor

References

1. Bahou WF, Nierman WC, Durkin AS, Potter CL, Demetrick DJ (September 1993). "Chromosomal assignment of the human thrombin receptor gene: localization to region q13 of chromosome 5". Blood 82 (5): 1532–7.2. Martorell L, Martínez-González J, Rodríguez C, Gentile M, Calvayrac O, Badimon L (February 2008). "Thrombin and protease-activated receptors (PARs) in atherothrombosis". Thromb. Haemost. 99 (2): 305–15.3. Bar-Shavit R, Maoz M, Yongjun Y, Groysman M, Dekel I, Katzav S (January 2002). "Signalling pathways induced by protease-activated receptors and integrins in T cells". Immunology 105 (1): 35–46.

H-SER-PHE-LEU-LEU-ARG-OH Preparation Products And Raw materials

Raw materials

Preparation Products

More

Less

H-SER-PHE-LEU-LEU-ARG-OH Suppliers

China 81 Germany 1 United States 11 Global 93

GL Biochem (Shanghai) Ltd

Tel: 21-61263452 13641803416
Fax: 86-21-61263399
Email: ymbetter@glbiochem.com
Country: China
ProdList: 9981
Advantage: 64

Shanghai Hanhong Scientific Co.,Ltd.

Tel
Country: China
ProdList: 42982
Advantage: 64

Chemsky (shanghai) International Co.,Ltd

Tel: 021-50135380
Email: shchemsky@sina.com
Country: China
ProdList: 15421
Advantage: 60

ApexBio Technology LLC

Tel: +1-832-696-8203
Fax: +1-832-641-3177
Email: info@apexbt.com
Country: United States
ProdList: 477
Advantage: 60

Wuxi Zhongkun Biochemical Technology Co., Ltd.

Tel: 0510-85629785 18013409632
Fax: 051085625359
Email: sales@reading-chemicals.com
Country: China
ProdList: 15185
Advantage: 58

Creative Peptides

Tel
Email: info@creative-peptides.com
Country: United States
ProdList: 6084
Advantage: 56

Nanjing Leon Biological Technology Co., Ltd.

Tel: 17705183659
Fax: 84523390
Email: sales@njleonbiotech.com
Country: China
ProdList: 5503
Advantage: 55

Nanjing Peptide Biotech Ltd.

Tel: 025-58361106-805 13082558573
Fax: 025-58361106-806
Email: liugang@njpeptide.com
Country: China
ProdList: 9961
Advantage: 55

Hangzhou Peptidego Biotech Co.,Ltd.

Tel: 0571-87213919
Fax: 0571-87213919
Email: eric@peptidego.com
Country: China
ProdList: 6347
Advantage: 58

Fan De(Beijing) Biotechnology Co., Ltd.

Tel: 15911056312
Email: liming@bio-fount.com
Country: China
ProdList: 9730
Advantage: 58

More

Less

View Lastest Price from H-SER-PHE-LEU-LEU-ARG-OH manufacturers

Henan Aochuang Chemical Co.,Ltd.

Product: H-SER-PHE-LEU-LEU-ARG-OH 141685-53-2
Price: US $0.00-0.00/kg
Min. Order: 1kg
Purity: 98%
Supply Ability: 1Ton
Release date: 2022-10-10

Career Henan Chemical Co

Product: H-SER-PHE-LEU-LEU-ARG-OH 141685-53-2
Price: US $7.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 100kg
Release date: 2020-02-13

141685-53-2, H-SER-PHE-LEU-LEU-ARG-OHRelated Search:

FLLRN TRAP-6 H-SER-PHE-LEU-LEU-ARG-NH2 H-SER-PHE-LEU-LEU-ARG-ASN-PRO-OH H-SER-PHE-LEU-LEU-ARG-ASN-PRO-ASN-ASP-LYS-TYR-GLU-PRO-PHE-NH2 TRAP-5 H-SER-PHE-LEU-LEU-ARG-ASN-NH2 L(+)-Arginine Argon H-LEU-ARG-OH H-LEU-LEU-ALA-OH H-SER-PHE-LEU-LEU-ARG-OH H-LEU-LEU-GLY-OH LEUPEPTIN

H-SER-PHE-LEU-LEU-ARG-OH

SFLLR, Coagulation Factor II Receptor (1-5) (huMan), PAR-1 (1-5) (huMan), ThroMbin Receptor (1-5) (huMan), ThroMbin Receptor Activator Peptide 5, Proteinase Activated Receptor 1 (1-5) (huMan)

SFLLR

SER-PHE-LEU-LEU-ARG

Thrombin Receptor Activator for Peptide 5 (TRAP-5)

L-Arginine, L-seryl-L-phenylalanyl-L-leucyl-L-leucyl-

L-Seryl-L-phenylalanyl-L-leucyl-L-leucyl-L-arginine

141685-53-2

C30H50N8O7

Peptide

Cardiovescular