H-SER-PHE-LEU-LEU-ARG-OH

ChemicalBook > CAS DataBase List > H-SER-PHE-LEU-LEU-ARG-OH

H-SER-PHE-LEU-LEU-ARG-OH

Product Name: H-SER-PHE-LEU-LEU-ARG-OH
CAS No.: 141685-53-2
Chemical Name: H-SER-PHE-LEU-LEU-ARG-OH
Synonyms: SFLLR;SER-PHE-LEU-LEU-ARG;H-SER-PHE-LEU-LEU-ARG-OH;Thrombin Receptor Activator for Peptide 5 (TRAP-5);L-Seryl-L-phenylalanyl-L-leucyl-L-leucyl-L-arginine;L-Arginine, L-seryl-L-phenylalanyl-L-leucyl-L-leucyl-;SFLLR, Coagulation Factor II Receptor (1-5) (huMan), PAR-1 (1-5) (huMan), ThroMbin Receptor (1-5) (huMan), ThroMbin Receptor Activator Peptide 5, Proteinase Activated Receptor 1 (1-5) (huMan)
CBNumber: CB3151835
Molecular Formula: C30H50N8O7
Formula Weight: 634.77
MOL File: 141685-53-2.mol

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H-SER-PHE-LEU-LEU-ARG-OH Property

Density: 1.32±0.1 g/cm3(Predicted)
storage temp.: -15°C
solubility: insoluble in EtOH; ≥14.63 mg/mL in H2O; ≥63.5 mg/mL in DMSO
form: solid
pka: 3.34±0.10(Predicted)

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

ApexBio Technology

Product number: A1036
Product name: ThrombinReceptorActivatorforPeptide5(TRAP-5)
Packaging: 5mg
Price: $45
Updated: 2021/12/16

ApexBio Technology

Product number: A1036
Product name: ThrombinReceptorActivatorforPeptide5(TRAP-5)
Packaging: 10mg
Price: $75
Updated: 2021/12/16

ChemScene

Product number: CS-0044800
Product name: ThrombinReceptorActivatorforPeptide5TRAP-5
Packaging: 1mg
Price: $80
Updated: 2021/12/16

ApexBio Technology

Product number: A1036
Product name: ThrombinReceptorActivatorforPeptide5(TRAP-5)
Packaging: 25mg
Price: $105
Updated: 2021/12/16

ChemScene

Product number: CS-0044800
Product name: ThrombinReceptorActivatorforPeptide5TRAP-5
Packaging: 5mg
Price: $180
Updated: 2021/12/16

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H-SER-PHE-LEU-LEU-ARG-OH Chemical Properties,Usage,Production

Biological Activity

thrombin receptor activator for peptide 5 (trap-5),(c30h50n8o7), a peptide with the sequence nh2-ser-phe-leu-leu-arg-cooh, mw= 634.76. coagulation factor ii (thrombin) receptor is a g protein-coupled receptor involved in the regulation of thrombotic response. proteolytic cleavage leads to the activation of the receptor(1). thrombin signalling in platelets contributes to hemostasis and thrombosis. endothelial pars participate in the regulation of vascular tone and permeability while in vascular smooth muscle they mediate contraction, proliferation, and hypertrophy. pars contribute to the pro-inflammatory response observed in atherosclerosis and restenosis. recent research has also implicated these novel receptors in muscle growth and bone cell differentiation and proliferation(2). in t cells, activation of par1, par2 and par3 induce tyrosine phosphorylation of vav1. activation of pars also led to an increase in tyrosine phosphorylation of zap-70 and slp-76, two key proteins in t cell receptor (tcr) signalling(3).figure1 formula of thrombin receptor activator for peptide 5 (trap-5)figure2 structure of thrombin receptor

References

1. Bahou WF, Nierman WC, Durkin AS, Potter CL, Demetrick DJ (September 1993). "Chromosomal assignment of the human thrombin receptor gene: localization to region q13 of chromosome 5". Blood 82 (5): 1532–7.2. Martorell L, Martínez-González J, Rodríguez C, Gentile M, Calvayrac O, Badimon L (February 2008). "Thrombin and protease-activated receptors (PARs) in atherothrombosis". Thromb. Haemost. 99 (2): 305–15.3. Bar-Shavit R, Maoz M, Yongjun Y, Groysman M, Dekel I, Katzav S (January 2002). "Signalling pathways induced by protease-activated receptors and integrins in T cells". Immunology 105 (1): 35–46.

H-SER-PHE-LEU-LEU-ARG-OH Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from H-SER-PHE-LEU-LEU-ARG-OH manufacturers

Henan Aochuang Chemical Co.,Ltd.

Product: H-SER-PHE-LEU-LEU-ARG-OH 141685-53-2
Price: US $0.00-0.00/kg
Min. Order: 1kg
Purity: 98%
Supply Ability: 1Ton
Release date: 2022-10-10

Career Henan Chemical Co

Product: H-SER-PHE-LEU-LEU-ARG-OH 141685-53-2
Price: US $7.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 100kg
Release date: 2020-02-13

141685-53-2, H-SER-PHE-LEU-LEU-ARG-OHRelated Search:

FLLRN TRAP-6 H-SER-PHE-LEU-LEU-ARG-NH2 H-SER-PHE-LEU-LEU-ARG-ASN-PRO-OH H-SER-PHE-LEU-LEU-ARG-ASN-PRO-ASN-ASP-LYS-TYR-GLU-PRO-PHE-NH2 TRAP-5 H-SER-PHE-LEU-LEU-ARG-ASN-NH2 L(+)-Arginine Argon H-LEU-ARG-OH H-LEU-LEU-ALA-OH H-SER-PHE-LEU-LEU-ARG-OH H-LEU-LEU-GLY-OH LEUPEPTIN

H-SER-PHE-LEU-LEU-ARG-OH

SFLLR, Coagulation Factor II Receptor (1-5) (huMan), PAR-1 (1-5) (huMan), ThroMbin Receptor (1-5) (huMan), ThroMbin Receptor Activator Peptide 5, Proteinase Activated Receptor 1 (1-5) (huMan)

SFLLR

SER-PHE-LEU-LEU-ARG

Thrombin Receptor Activator for Peptide 5 (TRAP-5)

L-Arginine, L-seryl-L-phenylalanyl-L-leucyl-L-leucyl-

L-Seryl-L-phenylalanyl-L-leucyl-L-leucyl-L-arginine

141685-53-2

C30H50N8O7

Peptide

Cardiovescular