methyl 2,5-dichloroisonicotinate
- Product Name
- methyl 2,5-dichloroisonicotinate
- CAS No.
- 623585-74-0
- Chemical Name
- methyl 2,5-dichloroisonicotinate
- Synonyms
- methyl 2,5-dichloroisonicotinate;Methyl 2,5-dichloropyridine-4-carboxylate;2,5-dichloroisonicotinic acid methyl ester;4-Pyridinecarboxylic acid, 2,5-dichloro-, methyl ester
- CBNumber
- CB31524858
- Molecular Formula
- C7H5Cl2NO2
- Formula Weight
- 206.03
- MOL File
- 623585-74-0.mol
methyl 2,5-dichloroisonicotinate Property
- Melting point:
- 28-29°
- storage temp.
- under inert gas (nitrogen or Argon) at 2-8°C
- Appearance
- White to off-white Solid-liquid mixture
Safety
- HazardClass
- IRRITANT
- HS Code
- 2933399990
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Danger
- Hazard statements
-
H226Flammable liquid and vapour
H290May be corrosive to metals
H314Causes severe skin burns and eye damage
- Precautionary statements
-
P210Keep away from heat/sparks/open flames/hot surfaces. — No smoking.
P233Keep container tightly closed.
P234Keep only in original container.
P240Ground/bond container and receiving equipment.
P241Use explosion-proof electrical/ventilating/lighting/…/equipment.
P242Use only non-sparking tools.
P243Take precautionary measures against static discharge.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P270Do not eat, drink or smoke when using this product.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P301+P330+P331IF SWALLOWED: Rinse mouth. Do NOT induce vomiting.
P303+P361+P353IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.
P370+P378In case of fire: Use … for extinction.
P390Absorb spillage to prevent material damage.
P403+P235Store in a well-ventilated place. Keep cool.
P405Store locked up.
P406Store in corrosive resistant/… container with a resistant inner liner.
P501Dispose of contents/container to..…
N-Bromosuccinimide Price
- Product number
- M695780
- Product name
- Methyl2,5-dichloroisonicotinate
- Packaging
- 2.5g
- Price
- $45
- Updated
- 2021/12/16
- Product number
- Y15204
- Product name
- Methyl2,5-dichloroisonicotinate
- Purity
- 98%
- Packaging
- 1g
- Price
- $35
- Updated
- 2021/12/16
- Product number
- 048062
- Product name
- Methyl 2,5-dichloroisonicotinate
- Purity
- >95%
- Packaging
- 500mg
- Price
- $120
- Updated
- 2021/12/16
- Product number
- Y15204
- Product name
- Methyl2,5-dichloroisonicotinate
- Purity
- 98%
- Packaging
- 5g
- Price
- $140
- Updated
- 2021/12/16
- Product number
- Z0736
- Product name
- Methyl2,5-dichloropyridine-4-carboxylate
- Packaging
- 1g
- Price
- $157
- Updated
- 2021/12/16
methyl 2,5-dichloroisonicotinate Chemical Properties,Usage,Production
Synthesis
67-56-1
88912-26-9
623585-74-0
General procedure for the synthesis of methyl 2,5-dichloroisonicotinate from methanol and 2,5-dichloroisonicotinic acid: concentrated sulfuric acid (0.5 mL) was slowly added to a methanolic solution of 2,5-dichloroisonicotinic acid, the reaction mixture was heated to reflux and the reaction was maintained for 12 hours. Upon completion of the reaction, the mixture was cooled to room temperature, neutralized to pH neutral with aqueous sodium bicarbonate and subsequently extracted with ethyl acetate. The organic phases were combined and the solvent was removed by evaporation under reduced pressure to afford the target product methyl 2,5-dichloroisonicotinate (6-2) in 89% yield.
References
[1] Bioorganic and Medicinal Chemistry Letters, 2008, vol. 18, # 19, p. 5186 - 5189
[2] Patent: WO2008/141385, 2008, A1. Location in patent: Page/Page column 83
[3] Patent: WO2013/72825, 2013, A1. Location in patent: Page/Page column 55
methyl 2,5-dichloroisonicotinate Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from methyl 2,5-dichloroisonicotinate manufacturers
- Product
- Methyl 2,5-dichloropyridine-4-carboxylate 623585-74-0
- Price
- US $2600.00/g
- Min. Order
- 1g
- Purity
- 99 %
- Supply Ability
- 500 Kg
- Release date
- 2024-11-12
- Product
- methyl 2,5-dichloroisonicotinate 623585-74-0
- Price
- US $1.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 200kg
- Release date
- 2020-01-09