TALIPEXOLE

Product Name: TALIPEXOLE
CAS No.: 101626-70-4
Chemical Name: TALIPEXOLE
Synonyms: Domin;Talipexol;TALIPEXOLE;Talipexolum;Talipexolum [latin];Talipexol [spanish];TALIPEXOLE USP/EP/BP;6-Allyl-5,6,7,8-tetrahydro-4H-thiazolo[4,5-d]azepin-2-amine;6-Allyl-2-amino-5,6,7,8-tetrahydro-4H-thiazolo[4,5-d]azepine;6-Allyl-5,6,7,8-tetrahydro-4H-[1,3]thiazolo[4,5-d]azepin-2-amine
CBNumber: CB3153213
Molecular Formula: C10H15N3S
Formula Weight: 209.31
MOL File: 101626-70-4.mol

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TALIPEXOLE Property

Boiling point:: 364.6±37.0 °C(Predicted)
Density: 1.167±0.06 g/cm3(Predicted)
storage temp.: Store at -20°C
solubility: Soluble in DMSO
form: Powder
pka: 7.22±0.20(Predicted)

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

American Custom Chemicals Corporation

Product number: API0009175
Product name: TALIPEXOLE
Purity: 95.00%
Packaging: 5MG
Price: $490
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: API0009175
Product name: TALIPEXOLE
Purity: 95.00%
Packaging: 10MG
Price: $520
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: API0009175
Product name: TALIPEXOLE
Purity: 95.00%
Packaging: 50MG
Price: $920
Updated: 2021/12/16

AvaChem

Product number: 2567B
Product name: Talipexole
Packaging: 1g
Price: $2900
Updated: 2021/12/16

Crysdot

Product number: CD31004840
Product name: Talipexole
Purity: 98+%
Packaging: 5mg
Price: $76
Updated: 2021/12/16

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TALIPEXOLE Chemical Properties,Usage,Production

Description

Domin was launched in Japan for Parkinson's disease. The compound is readily accessible in two steps from I-allylhexahydro-4H-azepin4-one. Its antiparkinson activity resides in the fact that talipexole is a selective agonist for presynaptic dopamine D₂ receptors with no D₁ receptor activity. It is a clonidine-like α₂-adrenoreptor agonist and has fewer GI side effects than bromocriptine the most widely used dopamine angonist. Also it is 70 times more potent than bromocriptine and has a more rapid onset of action. In addition to its anti-tremor activity there was a sedative effect but no emesis. The latter probably a result of talipexole's 5-HT₃ receptor antagonistic activity. Its metabolites have no biological activity, there was no development of tolerence and its effect could be enhanced by L-dopa.

Originator

Boehringer Ingelheim (Germany)

Definition

ChEBI: 6-prop-2-enyl-4,5,7,8-tetrahydrothiazolo[4,5-d]azepin-2-amine is an azepine.

brand name

Domin

TALIPEXOLE Preparation Products And Raw materials

Raw materials

Preparation Products

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TALIPEXOLE Suppliers

China 20 Europe 2 Germany 1 United Kingdom 4 United States 9 Global 36

LGM Pharma

Tel: 1-(800)-881-8210
Fax: 615-250-9817
Email: inquiries@lgmpharma.com
Country: United States
ProdList: 2127
Advantage: 70

MedChemexpress LLC

Tel: 021-58955995
Fax: 609-228-5909
Email: sales@medchemexpress.cn
Country: United States
ProdList: 4863
Advantage: 58

LETOPHARM LIMITED

Tel: +86-21-5821 5861
Fax: +86-21-5106 2861
Email: sales@letopharm.com
Country: China
ProdList: 2384
Advantage: 58

Tianjin Kailiqi Biotechnology Co., Ltd.

Tel: 15076683720
Fax: 022-23754520
Email: klq@cw-bio.com
Country: China
ProdList: 3444
Advantage: 55

Beijing Solarbio Science & Tecnology Co., Ltd.

Tel: 010-50973130 4009686088
Email: 3193328036@qq.com
Country: China
ProdList: 29797
Advantage: 68

Amadis Chemical Company Limited

Tel: 571-89925085
Fax: 0086-571-89925065
Email: sales@amadischem.com
Country: China
ProdList: 131981
Advantage: 58

Musechem

Tel: +1-800-259-7612
Fax: +1-800-259-7612
Email: info@musechem.com
Country: United States
ProdList: 4662
Advantage: 60

TargetMol Chemicals Inc.

Tel: +1-781-999-5354 +1-00000000000
Email: marketing@targetmol.com
Country: United States
ProdList: 19892
Advantage: 58

Dideu Industries Group Limited

Tel: +86-29-89586680 +86-15129568250
Email: 1026@dideu.com
Country: China
ProdList: 29016
Advantage: 58

Shaanxi Dideu Medichem Co. Ltd

Tel: +86-029-89586680 +86-18192503167
Fax: +86-29-88380327
Email: 1026@dideu.com
Country: China
ProdList: 9231
Advantage: 58

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View Lastest Price from TALIPEXOLE manufacturers

Dideu Industries Group Limited

Product: TALIPEXOLE 101626-70-4
Price: US $1.10/g
Min. Order: 1g
Purity: 99.9%
Supply Ability: 100 Tons Min
Release date: 2021-06-11

101626-70-4, TALIPEXOLERelated Search:

ARANIDIPINE Bendamustine Donepezil CALYXOL ISO-TALIPEXOLE, DIHYDROCHLORIDE TALIPEXOLE DIDHYDROCHLORIDE,Talipexole, 5,6,7,8-Tetrahydro-6-(2-propenyl)-4H-thiazolo[4,5-d]azepine-2-amine dihydrochloride,talipexole hydrochloride 2-(4-METHYL-THIAZOL-5-YL)-ETHYLAMINE TALIPEXOLE 2-(THIAZOL-4-YL)ETHYLAMINE AMTHAMINE DIHYDROBROMIDE 5,6,7,8-TETRAHYDRO-4H-THIAZOLO[4,5-D]AZEPINE 2-(2-AMINOTHIAZOL-4-YL)ETHYLAMINE

TALIPEXOLE

5，6，7，8-Tetrahydro-6-(2-propenyl)-4H-thiazolo[4，5-d]azepin-2-amine

Domin

6-Allyl-2-amino-5,6,7,8-tetrahydro-4H-thiazolo[4,5-d]azepine

6-Allyl-5,6,7,8-tetrahydro-4H-thiazolo[4,5-d]azepin-2-amine

Talipexol

Talipexol [spanish]

Talipexolum

Talipexolum [latin]

4H-Thiazolo[4,5-d]azepin-2-amine, 5,6,7,8-tetrahydro-6-(2-propen-1-yl)-

TALIPEXOLE USP/EP/BP

6-Allyl-5,6,7,8-tetrahydro-4H-[1,3]thiazolo[4,5-d]azepin-2-amine

101626-70-4