5-BROMO-2,3-DIHYDRO-ISOINDOL-1-ONE

Product Name: 5-BROMO-2,3-DIHYDRO-ISOINDOL-1-ONE
CAS No.: 552330-86-6
Chemical Name: 5-BROMO-2,3-DIHYDRO-ISOINDOL-1-ONE
Synonyms: 5-Bromo-1-isoindolinone;3-DIHYDRO-ISOINDOL-1-ONE;5-bromo isoinoline-1-one;5-BroMo-1-oxo-isoindoline;5-Bromo-1-Isoindolinone,96%;5-BroMo-1-isoindolinone, 96%;5-Bromoisoindolin-1-one≥ 98%(GC);4-BroMo-2,3-dihydroisoindol-1-one;5-BROMO-2,3-DIHYDRO-ISOINDOL-1-ONE;5-bromo-2,3-dihydroisoindole-1-one
CBNumber: CB31559892
Molecular Formula: C8H6BrNO
Formula Weight: 212.04
MOL File: 552330-86-6.mol

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5-BROMO-2,3-DIHYDRO-ISOINDOL-1-ONE Property

Melting point:: 267 °C
Boiling point:: 448.4±45.0 °C(Predicted)
Density: 1.666±0.06 g/cm3(Predicted)
storage temp.: Sealed in dry,Room Temperature
form: powder to crystal
pka: 13.75±0.20(Predicted)
color: White to Light yellow to Light red
InChI: InChI=1S/C8H6BrNO/c9-6-1-2-7-5(3-6)4-10-8(7)11/h1-3H,4H2,(H,10,11)
InChIKey: WJNKJYJCWXMBNV-UHFFFAOYSA-N
SMILES: C1(=O)C2=C(C=C(Br)C=C2)CN1

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Safety

HS Code: 2933998090

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

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N-Bromosuccinimide Price

TCI Chemical

Product number: B5328
Product name: 5-Bromoisoindolin-1-one
Purity: >98.0%(GC)
Packaging: 1g
Price: $84
Updated: 2025/07/31

TRC

Product number: B695420
Product name: 5-Bromoisoindolin-1-one
Packaging: 1g
Price: $70
Updated: 2021/12/16

Matrix Scientific

Product number: 073506
Product name: 5-Bromo-2,3-dihydroisoindol-1-one
Purity: 95+%
Packaging: 1g
Price: $49
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FB63118
Product name: 5-Bromo-2,3-dihydroisoindol-1-one
Packaging: 1g
Price: $76
Updated: 2021/12/16

Matrix Scientific

Product number: 073506
Product name: 5-Bromo-2,3-dihydroisoindol-1-one
Purity: 95+%
Packaging: 5g
Price: $145
Updated: 2021/12/16

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5-BROMO-2,3-DIHYDRO-ISOINDOL-1-ONE Chemical Properties,Usage,Production

Chemical Properties

Pink Solid

Uses

5-Bromoisoindolin-1-one was one of the reagents in discovering a new, selective 3-aminopyrazole based MK2-inhibitors.

Synthesis

78471-43-9

552330-86-6

The general procedure for the synthesis of 5-bromo-2,3-dihydroisoindol-1-one from 4-bromo-2-bromomethylbenzoic acid methyl ester was as follows: 4-bromo-2-bromomethylbenzoic acid methyl ester (3.70 g) was suspended in a methanol solution of 2 M ammonia (36 mL) and concentrated ammonium hydroxide (12 mL) and the reaction was carried out for 18 hours. After completion of the reaction, the solid product was collected by filtration to afford 5-bromo-2,3-dihydroisoindol-1-one as a colorless solid (2.3 g, 90% yield). The product was characterized by 1H NMR (300 MHz, CDCl3): δ 7.68 (m, 3H), 4.44 (s, 2H).

References

[1] Patent: WO2006/20879, 2006, A1. Location in patent: Page/Page column 66-67
[2] Patent: WO2015/52264, 2015, A1. Location in patent: Paragraph 0637; 0638
[3] Patent: WO2008/23161, 2008, A1. Location in patent: Page/Page column 121
[4] Patent: WO2005/73205, 2005, A1. Location in patent: Page/Page column 25
[5] Patent: US2007/49603, 2007, A1. Location in patent: Page/Page column 91-92

5-BROMO-2,3-DIHYDRO-ISOINDOL-1-ONE Preparation Products And Raw materials

Raw materials

Preparation Products

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5-BROMO-2,3-DIHYDRO-ISOINDOL-1-ONE Suppliers

Americas 1 Canada 1 China 194 Europe 1 India 3 Japan 1 United Kingdom 2 United States 16 Global 219

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View Lastest Price from 5-BROMO-2,3-DIHYDRO-ISOINDOL-1-ONE manufacturers

Career Henan Chemical Co

Product: 5-BROMO-2,3-DIHYDRO-ISOINDOL-1-ONE 552330-86-6
Price: US $1.00/KG
Min. Order: 1KG
Purity: 95%
Supply Ability: 500KG
Release date: 2018-08-19

Career Henan Chemical Co

Product: 5-BROMO-2,3-DIHYDRO-ISOINDOL-1-ONE 552330-86-6
Price: US $1.00/KG
Min. Order: 1KG
Purity: 95%
Supply Ability: 500KG
Release date: 2018-08-19

552330-86-6, 5-BROMO-2,3-DIHYDRO-ISOINDOL-1-ONERelated Search:

1,2-Bis(tetrabromophthalimido) ethane 3,4,5,6-TETRABROMOPHTHALIMIDE 4-Bromophthalimide 4-(5-BROMO-1,3-DIOXO-1,3-DIHYDRO-2H-ISOINDOL-2-YL)BUTANOIC ACID 3-(5-BROMO-1,3-DIOXO-1,3-DIHYDRO-2H-ISOINDOL-2-YL)PROPANOIC ACID 2-BENZYL-5-BROMOISOINDOLINE-1,3-DIONE (5-BROMO-1,3-DIOXO-1,3-DIHYDRO-ISOINDOL-2-YL)-ACETIC ACID AURORA 17308 (6-BROMO-3-OXO-2,3-DIHYDRO-1 H-ISOINDOL-1-YL)-ACETIC ACID AURORA 17476 N,N'-(methylenedi-p-phenylene)bis[3,4,5,6,-tetrabromophthalimide] AURORA 17477 AURORA 17474 2-(5-BROMO-1,3-DIOXO-1,3-DIHYDRO-ISOINDOL-2-YL)-3-METHYL-BUTYRIC ACID AURORA 22131 4,5,6,7-TETRABROMO-2-(OXIRAN-2-YLMETHYL)ISOINDOLINE-1,3-DIONE AURORA 17475 AURORA 9580

5-BROMO-2,3-DIHYDRO-ISOINDOL-1-ONE

5-BroMo-1-isoindolinone, 96%

4-BroMo-2,3-dihydroisoindol-1-one

5-BroMo-1-oxo-isoindoline

1H-Isoindol-1-one, 5-broMo-2,3-dihydro-

5-BroMo-2,3-dihydro-1H-isoindol-1-one

5-Bromo-2,3-dihydro-1-oxo-1H-isoindole

5-Bromo-1-Isoindolinone,96%

5-Bromoisoindolin-1-one≥ 98%(GC)

5-Bromo-2,3-dihydro-1H-isoindol-1-one 98%

3-DIHYDRO-ISOINDOL-1-ONE

5-bromo-2,3-dihydroisoindole-1-one

6(5H)-Phenanthridinone,3,11-dibromo-

5-bromo isoinoline-1-one

5-Bromo-2,3-dihydroisoindol-1-one, 98%min

5-Bromo-1-isoindolinone

552330-86-6