ChemicalBook > CAS DataBase List > (1R,3s,5S)-3-(3-Isopropyl-5-methyl-4H-1,2,4-triazol-4-yl)-8-azabicyclo[3.2.1]octane
(1R,3s,5S)-3-(3-Isopropyl-5-methyl-4H-1,2,4-triazol-4-yl)-8-azabicyclo[3.2.1]octane
- Product Name
- (1R,3s,5S)-3-(3-Isopropyl-5-methyl-4H-1,2,4-triazol-4-yl)-8-azabicyclo[3.2.1]octane
- CAS No.
- 423165-07-5
- Chemical Name
- (1R,3s,5S)-3-(3-Isopropyl-5-methyl-4H-1,2,4-triazol-4-yl)-8-azabicyclo[3.2.1]octane
- Synonyms
- UK 408027;Maraviroc Intermediate 2;Maraviroc interMediate(Tropinone);(1R,3s,5S)-3-(3-Isopropyl-5-methyl-4H-1,2,4-triazol-4-yl)-8-...;Des[1-(4,4-difluorocyclohexanecarboxamido)-1-phenylpropyl] Maraviroc;3-(3-isopropyl-5-methyl-4H-1,2,4-triazol-4-yl)-8-azabicyclo[3.2.1]octane;exo-3-(3-Isopropyl-5-methyl-4H-1,2,4-triazol-4-yl)-8-azabicyclo[3.2.1]octane;3-(3-Isopropyl-5-methyl-4H-1,2,4-triazol-4-yl)-exo-8-azabicyclo[3.2.1]octane;(1R,5S)-3-(3-methyl-5-propan-2-yl-1,2,4-triazol-4-yl)-8-azabicyclo[3.2.1]octane;(3-exo)-3-(3-Isopropyl-5-methyl-4H-1,2,4-triazol-4-yl]-8-azabicyclo[3.2.1]octane
- CBNumber
- CB31564885
- Molecular Formula
- C13H22N4
- Formula Weight
- 234.35
- MOL File
- 423165-07-5.mol
More
Less
(1R,3s,5S)-3-(3-Isopropyl-5-methyl-4H-1,2,4-triazol-4-yl)-8-azabicyclo[3.2.1]octane Property
- Melting point:
- 117 ºC
- Boiling point:
- 402.4±55.0 °C(Predicted)
- Density
- 1.31
- storage temp.
- Keep in dark place,Inert atmosphere,2-8°C
- solubility
- Chloroform
- form
- Solid
- pka
- 10.71±0.40(Predicted)
- color
- Off-White to Pale Yellow
- InChI
- InChI=1/C13H22N4/c1-8(2)13-16-15-9(3)17(13)12-6-10-4-5-11(7-12)14-10/h8,10-12,14H,4-7H2,1-3H3/t10-,11+,12-
- InChIKey
- CEIRCCADSFHOQD-ZSBIGDGJNA-N
- SMILES
- C(C1=NN=C(C)N1[C@@H]1C[C@H]2CC[C@H](N2)C1)(C)C |&1:7,9,12,r|
More
Less
Safety
- HS Code
- 2933592000
More
Less
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H332Harmful if inhaled
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
More
Less
N-Bromosuccinimide Price
TRC
- Product number
- D288810
- Product name
- Des[1-(4,4-difluorocyclohexanecarboxamido)-1-phenylpropyl]Maraviroc
- Packaging
- 10mg
- Price
- $235
- Updated
- 2021/12/16
AK Scientific
- Product number
- 5843AB
- Product name
- (1R,3s,5S)-3-(3-Isopropyl-5-methyl-4H-1,2,4-triazol-4-yl)-8-azabicyclo[3.2.1]octane
- Packaging
- 5g
- Price
- $437
- Updated
- 2021/12/16
American Custom Chemicals Corporation
- Product number
- APN0000582
- Product name
- MARAVIROC INTERMEDIATE
- Purity
- 95.00%
- Packaging
- 1MG
- Price
- $837.38
- Updated
- 2021/12/16
Medical Isotopes, Inc.
- Product number
- 8909
- Product name
- Des[1-(4,4-difluorocyclohexanecarboxamido)-1-phenylpropyl]Maraviroc
- Packaging
- 1mg
- Price
- $975
- Updated
- 2021/12/16
Ark Pharm
- Product number
- AK103286
- Product name
- exo-3-(3-Isopropyl-5-methyl-4H-1,2,4-triazol-4-yl)-8-azabicyclo[3.2.1]octane
- Purity
- 95+%
- Packaging
- 100mg
- Price
- $60
- Updated
- 2021/12/16
More
Less
(1R,3s,5S)-3-(3-Isopropyl-5-methyl-4H-1,2,4-triazol-4-yl)-8-azabicyclo[3.2.1]octane Chemical Properties,Usage,Production
Chemical Properties
Off-White to Pale Yellow Solid
Uses
A metabolite of Maraviroc.
Synthesis
A solution of 8-benzyl-3-(3-isopropyl-5-methyl-[1,2,4]triazol-4-yl)-8-aza-bicyclo[3.2.1]octane (2.0 g, 6.17 mmol) in methanol (30 mL) was treated with 10% palladium on carbon (0.25 g) under a hydrogen atmosphere (50 psi) at ambient temperature, overnight. The mixture was filtered through a pad of Celite and the filtrate was concentrated to give (1R,3s,5S)-3-(3-Isopropyl-5-methyl-4H-1,2,4-triazol-4-yl)-8-azabicyclo[3.2.1]octane. Yield: 1.36 g (94%).
(1R,3s,5S)-3-(3-Isopropyl-5-methyl-4H-1,2,4-triazol-4-yl)-8-azabicyclo[3.2.1]octane Preparation Products And Raw materials
Raw materials
Preparation Products
More
Less
(1R,3s,5S)-3-(3-Isopropyl-5-methyl-4H-1,2,4-triazol-4-yl)-8-azabicyclo[3.2.1]octane Suppliers
More
Less
View Lastest Price from (1R,3s,5S)-3-(3-Isopropyl-5-methyl-4H-1,2,4-triazol-4-yl)-8-azabicyclo[3.2.1]octane manufacturers
Henan Fengda Chemical Co., Ltd
- Product
- (1R,3s,5S)-3-(3-Isopropyl-5-methyl-4H-1,2,4-triazol-4-yl)-8-azabicyclo[3.2.1]octane 423165-07-5
- Price
- US $101.00-1.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- g-kg-tons, free sample is available
- Release date
- 2023-12-28
Hebei Yanxi Chemical Co., Ltd.
- Product
- (1R,3s,5S)-3-(3-Isopropyl-5-methyl-4H-1,2,4-triazol-4-yl)-8-azabicyclo[3.2.1]octane 423165-07-5
- Price
- US $0.00/kg
- Min. Order
- 1kg
- Purity
- 0.99
- Supply Ability
- 20tons
- Release date
- 2023-10-07
Honest Joy Holdings Limited
- Product
- (1R,3s,5S)-3-(3-Isopropyl-5-methyl-4H-1,2,4-triazol-4-yl)-8-azabicyclo[3.2.1]octane 423165-07-5
- Price
- US $0.00/KG
- Min. Order
- 1KG
- Purity
- 98.8%
- Supply Ability
- 100 tons
- Release date
- 2022-01-17
423165-07-5, (1R,3s,5S)-3-(3-Isopropyl-5-methyl-4H-1,2,4-triazol-4-yl)-8-azabicyclo[3.2.1]octaneRelated Search:
Bensulfuron methyl
Thiophanate-methyl
ISOPROPYL LAURATE
Isopropyl alcohol
2,2,4-Trimethylpentane
1-OCTANESULFONIC ACID, SODIUM SALT, MONOHYDRATE
N-OCTANE
1-Bromooctane
Methyl acrylate
Methylparaben
Kresoxim-methyl
Methyl
Methyl bromide
6-ACETHYOXY-8-METHYL-8-AZABICYCLO(3.2.1)OCTAN-3-ONE
2-CARBOMETHOXY-3-TROPINONE
(+/-)-exo-6-Hydroxytropinone
N-Carbethoxy-4-tropinone
N-Boc-Nortropinone