N-Carbethoxy-4-tropinone

Product Name: N-Carbethoxy-4-tropinone
CAS No.: 32499-64-2
Chemical Name: N-Carbethoxy-4-tropinone
Synonyms: n-(carboethoxy)tropinone;N-CARBETHOXY-4-TROPINONE;N-Carbethoxy-4-nortropinone;N-(CARBOETHOXY)NORTROPINONE;N-(ETHOXYCARBONYL)TROPINONE;Ethyl 3-Oxo-8-Azabicyclo(3.;N-CARBETHOXY-4-TROPINONE,98%;N-(ETHOXYCAZBONYL)NORTROPINONE;N-(Ethoxycarbonyl)tropinone,99%;N-ethoxycarbonylnortropan-3-one
CBNumber: CB0306544
Molecular Formula: C10H15NO3
Formula Weight: 197.23
MOL File: 32499-64-2.mol

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N-Carbethoxy-4-tropinone Property

Boiling point:: 152-153°C 11mm
Density: 1.1575 (rough estimate)
refractive index: 1.4876-1.4896
Flash point:: 152-153°C/11mm
storage temp.: Sealed in dry,Room Temperature
pka: -1.66±0.20(Predicted)
form: Liquid
color: Clear slightly yellow to light brown
BRN: 1530944
CAS DataBase Reference: 32499-64-2(CAS DataBase Reference)

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Safety

Safety Statements: 24/25
HS Code: 29399990

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

TCI Chemical

Product number: E0834
Product name: N-(Ethoxycarbonyl)nortropinone
Purity: >98.0%(GC)
Packaging: 5g
Price: $156
Updated: 2025/07/31

TCI Chemical

Product number: E0834
Product name: N-(Ethoxycarbonyl)nortropinone
Purity: >98.0%(GC)
Packaging: 25g
Price: $623
Updated: 2025/07/31

TRC

Product number: C176220
Product name: N-Carbethoxy-4-tropinone
Packaging: 100mg
Price: $45
Updated: 2021/12/16

TRC

Product number: C176220
Product name: N-Carbethoxy-4-tropinone
Packaging: 500mg
Price: $65
Updated: 2021/12/16

TRC

Product number: C176220
Product name: N-Carbethoxy-4-tropinone
Packaging: 1g
Price: $75
Updated: 2021/12/16

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N-Carbethoxy-4-tropinone Chemical Properties,Usage,Production

Chemical Properties

CLEAR SLIGHTLY YELLOW TO LIGHT BROWN LIQUID

Synthesis

532-24-1

541-41-3

32499-64-2

To a dry 500 mL round-bottomed flask were added a stirrer, 8-methyl-8-azabicyclo[3.2.1]octan-3-one (10.0 g, 0.072 mol) and potassium carbonate (0.050 g). Anhydrous toluene (90 mL) was added, followed by slow dropwise addition of ethyl chloroformate (21 mL, 0.22 mol) via syringe. A condenser tube and nitrogen bubbler were installed and the reaction was heated to reflux with stirring overnight. Upon completion of the reaction, the mixture was concentrated under reduced pressure and the resulting brown oil was dissolved in dichloromethane (100 mL) and washed with water (100 mL). The organic and aqueous layers were separated in a partition funnel and the aqueous layer was extracted with dichloromethane (3 x 50 mL). The organic phases were combined, dried over anhydrous sodium sulfate, filtered and concentrated under reduced pressure. The residue was purified by silica gel column chromatography (eluent: ethyl acetate/hexane, 1:3) to afford ethyl 3-oxo-8-azabicyclo[3.2.1]octane-8-carboxylate (13.1 g, 92% yield) as a light yellow oil.1H NMR (δ): 4.51 (br s, 2H), 4.16 (q, J = 7.2 Hz, 2H), 2.63 (br s , 2H), 2.31 (dd, J = 17.4, 1.6 Hz, 2H), 2.07-2.03 (m, 2H), 1.65 (d, J = 7.6 Hz, 2H), 1.25 (t, J = 7.2 Hz, 3H).13C NMR (δ): 208.3, 154.1, 61.6, 53.2, 49.1, 29.5 (2), 28.8 (2), 14.8 (2), 28.8 (2), 29.5 (2), 29.5 (2), 28.8 (2), 28.8 (2), 28.8 (2), 29.5 (2) 28.8 (2), 14.9.

References

[1] Bioorganic and Medicinal Chemistry Letters, 2003, vol. 13, # 4, p. 629 - 632
[2] Journal of Heterocyclic Chemistry, 2004, vol. 41, # 4, p. 569 - 574
[3] Bioorganic and Medicinal Chemistry, 2011, vol. 19, # 24, p. 7551 - 7558
[4] Patent: CN105294674, 2016, A. Location in patent: Paragraph 0147; 0148; 0149
[5] Patent: WO2018/140876, 2018, A1. Location in patent: Page/Page column 216

N-Carbethoxy-4-tropinone Preparation Products And Raw materials

Raw materials

Preparation Products

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N-Carbethoxy-4-tropinone Suppliers

Americas 1 Belgium 1 China 93 Europe 1 Germany 2 India 5 Japan 3 Switzerland 1 United Kingdom 9 United States 24 Global 140

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View Lastest Price from N-Carbethoxy-4-tropinone manufacturers

Hebei Yanxi Chemical Co., Ltd.

Product: N-Carbethoxy-4-tropinone 32499-64-2
Price: US $0.00/kg
Min. Order: 1kg
Purity: 0.99
Supply Ability: 20 tons
Release date: 2023-10-07

Hebei Yanxi Chemical Co., Ltd.

Product: N-Carbethoxy-4-tropinone 32499-64-2
Price: US $0.00/kg
Min. Order: 1kg
Purity: 0.99
Supply Ability: 20 tons
Release date: 2023-10-07

Zhuozhou Wenxi import and Export Co., Ltd

Product: N-Carbethoxy-4-tropinone 32499-64-2
Price: US $15.00-10.00/KG
Min. Order: 1KG
Purity: 99%+ HPLC
Supply Ability: Monthly supply of 1 ton
Release date: 2021-08-11

32499-64-2, N-Carbethoxy-4-tropinoneRelated Search:

Tris(trimethylsilyl)phosphate N-Carbobenzyloxyglycine N-OCTANE Oxyfluorfen 3-Nitroacetophenone Ethylparaben Oxygen-fluorine acid Tropinone Tropisetron hydrochloride Ethanol Tropisetron Levofloxacin carboxylic acid Ethyl acetate Acetophenone (1R,3s,5S)-3-(3-Isopropyl-5-methyl-4H-1,2,4-triazol-4-yl)-8-azabicyclo[3.2.1]octane Diethyl ether N-Boc-Nortropinone Cycloheptanone

n-(carboethoxy)tropinone

3-Oxo-8-azabicylo[3.2.1]octane-8-carboxylic acid

ethyl 3-oxo-8-azabicyclo(3.2.1)octane-8-carboxylate

N-(Carboethoxy)tropinone~3-Oxo-8-azabicyclo[3.2.1]octane-8-carboxylic acid ethyl ester

N-ethoxycarbonylnortropan-3-one

N-(Ethoxycarbonyl)tropinone,99%

N-(ETHOXYCAZBONYL)NORTROPINONE

N-(Ethoxycarbonyl)nortropinone, 99%

N-CARBETHOXY-4-TROPINONE,98%

Ethyl 3-Oxo-8-Azabicyclo(3.

N-Carbethoxy-4-nortropinone

N-(CARBOETHOXY)NORTROPINONE

N-(ETHOXYCARBONYL)TROPINONE

N-CARBETHOXY-4-TROPINONE

3-Oxo-8-azabicylo[3.2.1]octane-8-carboxylic acid ethyl ester

8-(Ethoxycarbonyl)-8-azabicyclo[3.2.1]octan-3-one

3-OXO-8-AZABICYCLO[3.2.1]OCTANE-8-CARBOXYLIC ACID ETHYL ESTER

8-Azabicyclo[3.2.1]octane-8-carboxylic acid, 3-oxo-, ethyl ester

N-(Ethoxycarbonyl)nortropinone 97%

(1S,5R)-3-oxo-8-azabicyclo[3.2.1]octane-8-carboxylic acid ethyl ester

ETHYL 3-OXONORTROPANE-8-CARBOXYLATE

N-(Ethoxycarbonyl)nortropinone&gt

32499-64-2

C10H15NO3

Miscellaneous Biochemicals