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Tropisetron hydrochloride

Product Name
Tropisetron hydrochloride
CAS No.
105826-92-4
Chemical Name
Tropisetron hydrochloride
Synonyms
TROPISETRON HCL;Novaban;SDZ-ICS 930;Novaban / ICS 205930;TropisetronHcl/Mesylate;ropisetronhydrochloride;α-L-Rhamnose monohydrate;Tropisetran hydrochloride;TROPISETRON HYDROCHLORIDE;Triopisetron hydrochloride
CBNumber
CB9761399
Molecular Formula
C17H21ClN2O2
Formula Weight
320.81
MOL File
105826-92-4.mol
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Tropisetron hydrochloride Property

Melting point:
283-285°C
RTECS 
NL6012520
storage temp. 
2-8°C
solubility 
H2O: >10mg/mL
form 
solid
color 
White to Light yellow
Water Solubility 
Soluble in water
Merck 
14,9783
InChI
InChI=1/C17H20N2O2.ClH/c1-19-11-6-7-12(19)9-13(8-11)21-17(20)15-10-18-16-5-3-2-4-14(15)16;/h2-5,10-13,15H,6-9H2,1H3;1H/t11-,12+,13?,15?;
InChIKey
ZAOQBEAHJFSJLY-NBVCILBMNA-N
SMILES
C12C=CC=CC=1N=CC2C(=O)OC1C[C@]2([H])N(C)[C@@]([H])(CC2)C1.Cl |&1:14,18,r|
CAS DataBase Reference
105826-92-4(CAS DataBase Reference)
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Safety

RIDADR 
2811
WGK Germany 
3
HazardClass 
6.1
PackingGroup 
III
HS Code 
29399990
Toxicity
mouse,LD50,intravenous,37900ug/kg (37.9mg/kg),Gekkan Yakuji. Pharmaceuticals Monthly. Vol. 40, Pg. 2445, 1998.
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H301Toxic if swalloed

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P321Specific treatment (see … on this label).

P405Store locked up.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
Y0000616
Product name
Tropisetron hydrochloride
Purity
European Pharmacopoeia (EP) Reference Standard
Packaging
y0000616
Price
$220
Updated
2024/03/01
Sigma-Aldrich
Product number
T104
Product name
Tropisetron monohydrochloride
Purity
solid, ≥98% (HPLC)
Packaging
50mg
Price
$344.8
Updated
2024/03/01
TCI Chemical
Product number
T2743
Product name
Tropisetron Hydrochloride
Purity
>98.0%(HPLC)(T)
Packaging
1g
Price
$133
Updated
2024/03/01
TCI Chemical
Product number
T2743
Product name
Tropisetron Hydrochloride
Purity
>98.0%(HPLC)(T)
Packaging
5g
Price
$455
Updated
2024/03/01
Alfa Aesar
Product number
J62807
Product name
3-Tropanylindole-3-carboxylate hydrochloride
Packaging
100mg
Price
$206.65
Updated
2024/03/01
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Tropisetron hydrochloride Chemical Properties,Usage,Production

Chemical Properties

White to Off-White Crystalline Solid

Uses

Specific serotonin (5-HT3) receptor antagonist. Antiemetic.

Uses

A selective 5-HT3 serotonin receptor antagonist

Definition

ChEBI: A hydrochloride obtained by combining equimolar amounts of tropisetron and hydrogen chloride.

Biological Activity

Potent, orally active 5-HT 3 receptor antagonist. Antiemetic.

Biochem/physiol Actions

Tropisetron a selective serotonin 5-HT3 receptor antagonist is used mainly as an antiemetic to treat nausea and vomiting following chemotherapy . In the treatment of fibromyalgia syndrome (FMS) tropisetron reduced not only pain perception but also had a favourable effect on cardiac dysfunction during treatment.

storage

Room temperature (desiccate)

Tropisetron hydrochloride Preparation Products And Raw materials

Raw materials

Preparation Products

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Tropisetron hydrochloride Suppliers

Jinan Rouse Industry Co., Ltd.
Tel
0531-0531-82929600 18615510361
Fax
053182921652
Email
sale@rousechem.com
Country
China
ProdList
175
Advantage
58
J & K SCIENTIFIC LTD.
Tel
010-82848833 400-666-7788
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
94838
Advantage
76
Meryer (Shanghai) Chemical Technology Co., Ltd.
Tel
4006608290; 18621169109
Fax
86-21-61259102
Email
market03@meryer.com
Country
China
ProdList
40241
Advantage
62
3B Pharmachem (Wuhan) International Co.,Ltd.
Tel
821-50328103-801 18930552037
Fax
86-21-50328109
Email
3bsc@sina.com
Country
China
ProdList
15848
Advantage
69
Chembest Research Laboratories Limited
Tel
021-20908456
Fax
021-58180499
Email
sales@BioChemBest.com
Country
China
ProdList
6013
Advantage
61
TCI (Shanghai) Development Co., Ltd.
Tel
021-67121386
Fax
021-67121385
Email
Sales-CN@TCIchemicals.com
Country
China
ProdList
24539
Advantage
81
Energy Chemical
Tel
021-021-58432009 400-005-6266
Fax
021-58436166
Email
sales8178@energy-chemical.com
Country
China
ProdList
44751
Advantage
61
Beijing Mediking Biopharm Co., Ltd
Tel
010-81769521,89753524,81760121 15901403431
Fax
+86-10-81769652
Email
sales01@mediking.cn
Country
China
ProdList
99
Advantage
68
Capot Chemical Co., Ltd
Tel
+86 (0) 571 85 58 67 18
Fax
0086-571-85864795
Email
sales@capotchem.com
Country
China
ProdList
18217
Advantage
66
Ascent Scientific
Tel
4401179829988
Fax
4402030 700 369
Email
customerservice@ascentscientific.co.uk
Country
United Kingdom
ProdList
279
Advantage
60
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View Lastest Price from Tropisetron hydrochloride manufacturers

Henan Fengda Chemical Co., Ltd
Product
Tropisetron hydrochloride 105826-92-4
Price
US $122.00-1.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
g-kg-tons, free sample is available
Release date
2024-01-11
Hebei Duling International Trade Co. LTD
Product
Tropisetron hydrochloride 105826-92-4
Price
US $24.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
1000kg
Release date
2023-03-15
WUHAN FORTUNA CHEMICAL CO., LTD
Product
Tropisetron hydrochloride 105826-92-4
Price
US $0.00/Kg/Bag
Min. Order
1KG
Purity
99%-101%,EP
Supply Ability
10kg
Release date
2021-08-05

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