Tropisetron hydrochloride

Product Name: Tropisetron hydrochloride
CAS No.: 105826-92-4
Chemical Name: Tropisetron hydrochloride
Synonyms: TROPISETRON HCL;Novaban;SDZ-ICS 930;Novaban / ICS 205930;TropisetronHcl/Mesylate;ropisetronhydrochloride;α-L-Rhamnose monohydrate;Tropisetran hydrochloride;TROPISETRON HYDROCHLORIDE;Triopisetron hydrochloride
CBNumber: CB9761399
Molecular Formula: C17H21ClN2O2
Formula Weight: 320.81
MOL File: 105826-92-4.mol

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Tropisetron hydrochloride Property

Melting point:: 283-285°C
RTECS: NL6012520
storage temp.: 2-8°C
solubility: H2O: >10mg/mL
form: solid
color: White to Light yellow
Water Solubility: Soluble in water
Merck: 14,9783
InChI: InChI=1/C17H20N2O2.ClH/c1-19-11-6-7-12(19)9-13(8-11)21-17(20)15-10-18-16-5-3-2-4-14(15)16;/h2-5,10-13,15H,6-9H2,1H3;1H/t11-,12+,13?,15?;
InChIKey: ZAOQBEAHJFSJLY-NBVCILBMNA-N
SMILES: C12C=CC=CC=1N=CC2C(=O)OC1C[C@]2([H])N(C)[C@@]([H])(CC2)C1.Cl |&1:14,18,r|
CAS DataBase Reference: 105826-92-4(CAS DataBase Reference)

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Safety

RIDADR: 2811
WGK Germany: 3
HazardClass: 6.1
PackingGroup: III
HS Code: 29399990
Toxicity: mouse,LD50,intravenous,37900ug/kg (37.9mg/kg),Gekkan Yakuji. Pharmaceuticals Monthly. Vol. 40, Pg. 2445, 1998.

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H301Toxic if swalloed

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P321Specific treatment (see … on this label).

P405Store locked up.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: Y0000616
Product name: Tropisetron hydrochloride
Purity: European Pharmacopoeia (EP) Reference Standard
Packaging: y0000616
Price: $220
Updated: 2024/03/01

Sigma-Aldrich

Product number: T104
Product name: Tropisetron monohydrochloride
Purity: solid, ≥98% (HPLC)
Packaging: 50mg
Price: $344.8
Updated: 2024/03/01

TCI Chemical

Product number: T2743
Product name: Tropisetron Hydrochloride
Purity: >98.0%(HPLC)(T)
Packaging: 1g
Price: $133
Updated: 2024/03/01

TCI Chemical

Product number: T2743
Product name: Tropisetron Hydrochloride
Purity: >98.0%(HPLC)(T)
Packaging: 5g
Price: $455
Updated: 2024/03/01

Alfa Aesar

Product number: J62807
Product name: 3-Tropanylindole-3-carboxylate hydrochloride
Packaging: 100mg
Price: $206.65
Updated: 2024/03/01

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Tropisetron hydrochloride Chemical Properties,Usage,Production

Chemical Properties

White to Off-White Crystalline Solid

Uses

Specific serotonin (5-HT3) receptor antagonist. Antiemetic.

Uses

A selective 5-HT3 serotonin receptor antagonist

Definition

ChEBI: A hydrochloride obtained by combining equimolar amounts of tropisetron and hydrogen chloride.

Biological Activity

Potent, orally active 5-HT 3 receptor antagonist. Antiemetic.

Biochem/physiol Actions

Tropisetron a selective serotonin 5-HT3 receptor antagonist is used mainly as an antiemetic to treat nausea and vomiting following chemotherapy . In the treatment of fibromyalgia syndrome (FMS) tropisetron reduced not only pain perception but also had a favourable effect on cardiac dysfunction during treatment.

storage

Room temperature (desiccate)

Tropisetron hydrochloride Preparation Products And Raw materials

Raw materials

Preparation Products

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Tropisetron hydrochloride Suppliers

Canada 1 China 263 Europe 2 France 2 Germany 3 India 6 Japan 1 South Korea 1 Switzerland 1 United Kingdom 11 United States 33 Global 324

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View Lastest Price from Tropisetron hydrochloride manufacturers

Henan Fengda Chemical Co., Ltd

Product: Tropisetron hydrochloride 105826-92-4
Price: US $122.00-1.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: g-kg-tons, free sample is available
Release date: 2024-01-11

Hebei Duling International Trade Co. LTD

Product: Tropisetron hydrochloride 105826-92-4
Price: US $24.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 1000kg
Release date: 2023-03-15

WUHAN FORTUNA CHEMICAL CO., LTD

Product: Tropisetron hydrochloride 105826-92-4
Price: US $0.00/Kg/Bag
Min. Order: 1KG
Purity: 99%-101%,EP
Supply Ability: 10kg
Release date: 2021-08-05

105826-92-4, Tropisetron hydrochlorideRelated Search:

Indole Tropisetron Methyl salicylate Topotecan hydrochloride Indole-3-butyric acid Indometacin Kresoxim-methyl Indole-3-acetic acid 1-AdaMantanethylaMine Tribenuron methyl RESMETHRIN Thiophanate-methyl Methyl 8-Azabicyclo[3.2.1]octan-3-ol, 8-methyl-, hydrochloride (1:1), (3-endo)- TROPISETRON IMPURITY B Sibutramine hydrochloride Methyl bromide Tramadol hydrochloride

3-TROPANYLINDOLE-3-CARBOXYLATE HYDROCHLORIDE

(3-ENDO)-8-METHYL-8-AZABICYCLO[3.2.1]OCT-3-YL 1H-INDOLE-3-CARBOXYLIC ACID ESTER MONOHYDROCHLORIDE

TROPISETRON HYDROCHLORIDE 98.5-101.5%

TropisetronHcl/Mesylate

1H-Indole-3-carboxylic acid, (3-endo)-8-methyl-8-azabicyclo[3.2.1]oct-3-yl ester, hydrochloride (1:1)

1H-Indole-3-carboxylic acid (3-endo)-8-methyl-8-azabicyclo[3.2.1]oct-3-yl ester hydrochloride

Novaban

SDZ-ICS 930

3-Tropanylindole-3-carboxylate monohydrochloride, ICS-205,930, Navoban, 1H-Indole-3-carboxylic acid (3-endo)-8-methyl-8-azabicyclo[3.2.1]oct-3-yl ester monohydrochloride

Tropisetron monohydrochloride

Novaban / ICS 205930

Tropisetran hydrochloride

(3-endo)-8-Methyl-8-azabicyclo[3.2.1]oct-3-yl 1H-Indole-3-carboxylate Hydrochloride

3-Tropanylindole-3-carboxylate monohydrochloride

Tropisetron hydrochloride, >=99%

TROPISETRON HCL

TROPISETRON HYDROCHLORIDE

(1S)-8-methyl-8-azabicyclo[3.2.1]octan-3-yl 1H-indole-3-carboxylate hydrochloride

Tropisetron monohydrochloride, 99%, a 5-HT3 receptor antagonist and α7-nicotinic receptor agonist

Tropisetron hydrochloride CRS

(1R,3R,5S)-8-methyl-8-azabicyclo[3.2.1]octan-3-yl 1H-indole-3-carboxylate hydrochloride

ropisetronhydrochloride

Tropisetron hydrochloride USP/EP/BP

Triopisetron hydrochloride

endo-8-Methyl-8-azabicyclo[3.2.1]octan-3-yl 1H-indole-3-carboxylate hydrochloride

Tropisetron HCl (SDZ-ICS-930 HCl)

CAS 105826-92-4 Tropisetron hydrochloride

α-L-Rhamnose monohydrate

Tropisetron Hydrochloride, ≥ 98.0%

105826-92-4

105825-92-4

89656-68-4

C17H20N2O2ClH

C17H20N2O2HCl

Serotonin

Serotonin receptor

Heterocycles

Intermediates & Fine Chemicals

Pharmaceuticals

NAVOBAN

zjh

Antiemetic