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Tropisetron hydrochloride

Product Name
Tropisetron hydrochloride
CAS No.
105826-92-4
Chemical Name
Tropisetron hydrochloride
Synonyms
TROPISETRON HCL;Novaban;SDZ-ICS 930;Novaban / ICS 205930;TropisetronHcl/Mesylate;ropisetronhydrochloride;α-L-Rhamnose monohydrate;Tropisetran hydrochloride;TROPISETRON HYDROCHLORIDE;Triopisetron hydrochloride
CBNumber
CB9761399
Molecular Formula
C17H21ClN2O2
Formula Weight
320.81
MOL File
105826-92-4.mol
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Tropisetron hydrochloride Property

Melting point:
283-285°C
RTECS 
NL6012520
storage temp. 
2-8°C
solubility 
H2O: >10mg/mL
form 
solid
color 
White to Light yellow
Water Solubility 
Soluble in water
Merck 
14,9783
InChI
InChI=1/C17H20N2O2.ClH/c1-19-11-6-7-12(19)9-13(8-11)21-17(20)15-10-18-16-5-3-2-4-14(15)16;/h2-5,10-13,15H,6-9H2,1H3;1H/t11-,12+,13?,15?;
InChIKey
ZAOQBEAHJFSJLY-NBVCILBMNA-N
SMILES
C12C=CC=CC=1N=CC2C(=O)OC1C[C@]2([H])N(C)[C@@]([H])(CC2)C1.Cl |&1:14,18,r|
CAS DataBase Reference
105826-92-4(CAS DataBase Reference)
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Safety

RIDADR 
2811
WGK Germany 
3
HazardClass 
6.1
PackingGroup 
III
HS Code 
29399990
Toxicity
mouse,LD50,intravenous,37900ug/kg (37.9mg/kg),Gekkan Yakuji. Pharmaceuticals Monthly. Vol. 40, Pg. 2445, 1998.
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H301Toxic if swalloed

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P321Specific treatment (see … on this label).

P405Store locked up.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
Y0000616
Product name
Tropisetron hydrochloride
Purity
European Pharmacopoeia (EP) Reference Standard
Packaging
y0000616
Price
$220
Updated
2024/03/01
Sigma-Aldrich
Product number
T104
Product name
Tropisetron monohydrochloride
Purity
solid, ≥98% (HPLC)
Packaging
50mg
Price
$344.8
Updated
2024/03/01
TCI Chemical
Product number
T2743
Product name
Tropisetron Hydrochloride
Purity
>98.0%(HPLC)(T)
Packaging
1g
Price
$133
Updated
2024/03/01
TCI Chemical
Product number
T2743
Product name
Tropisetron Hydrochloride
Purity
>98.0%(HPLC)(T)
Packaging
5g
Price
$455
Updated
2024/03/01
Alfa Aesar
Product number
J62807
Product name
3-Tropanylindole-3-carboxylate hydrochloride
Packaging
100mg
Price
$206.65
Updated
2024/03/01
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Tropisetron hydrochloride Chemical Properties,Usage,Production

Chemical Properties

White to Off-White Crystalline Solid

Uses

Specific serotonin (5-HT3) receptor antagonist. Antiemetic.

Uses

A selective 5-HT3 serotonin receptor antagonist

Definition

ChEBI: A hydrochloride obtained by combining equimolar amounts of tropisetron and hydrogen chloride.

Biological Activity

Potent, orally active 5-HT 3 receptor antagonist. Antiemetic.

Biochem/physiol Actions

Tropisetron a selective serotonin 5-HT3 receptor antagonist is used mainly as an antiemetic to treat nausea and vomiting following chemotherapy . In the treatment of fibromyalgia syndrome (FMS) tropisetron reduced not only pain perception but also had a favourable effect on cardiac dysfunction during treatment.

storage

Room temperature (desiccate)

Tropisetron hydrochloride Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from Tropisetron hydrochloride manufacturers

Henan Fengda Chemical Co., Ltd
Product
Tropisetron hydrochloride 105826-92-4
Price
US $122.00-1.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
g-kg-tons, free sample is available
Release date
2024-01-11
Hebei Duling International Trade Co. LTD
Product
Tropisetron hydrochloride 105826-92-4
Price
US $24.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
1000kg
Release date
2023-03-15
WUHAN FORTUNA CHEMICAL CO., LTD
Product
Tropisetron hydrochloride 105826-92-4
Price
US $0.00/Kg/Bag
Min. Order
1KG
Purity
99%-101%,EP
Supply Ability
10kg
Release date
2021-08-05

105826-92-4, Tropisetron hydrochlorideRelated Search:

Indole Tropisetron Methyl salicylate Topotecan hydrochloride Indole-3-butyric acid Indometacin Kresoxim-methyl Indole-3-acetic acid 1-AdaMantanethylaMine Tribenuron methyl RESMETHRIN Thiophanate-methyl Methyl 8-Azabicyclo[3.2.1]octan-3-ol, 8-methyl-, hydrochloride (1:1), (3-endo)- TROPISETRON IMPURITY B Sibutramine hydrochloride Methyl bromide Tramadol hydrochloride

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