2-(CHLOROMETHYL)-1-METHYL-1H-IMIDAZOLE HYDROCHLORIDE

Product Name: 2-(CHLOROMETHYL)-1-METHYL-1H-IMIDAZOLE HYDROCHLORIDE
CAS No.: 78667-04-6
Chemical Name: 2-(CHLOROMETHYL)-1-METHYL-1H-IMIDAZOLE HYDROCHLORIDE
Synonyms: 2-Chloromethyl-1-methyl-1H-imida;2-CHLOROMETHYL-1-METHYL-1H-IMIDAZOLE HCL;2-(Chloromethyl)-1-methylimidazole hydrochloride;1-Methyl-2-(chloromethyl)imidazole hydrochloride;2-(CHLOROMETHYL)-1-METHYL-1H-IMIDAZOLE HYDROCHLORIDE;2-(Chloromethyl)-1-methyl-1H-imidazole hydrochloride 95%;1H-IMidazole,2-(chloroMethyl)-1-Methyl-, hydrochloride (1:1)
CBNumber: CB3168271
Molecular Formula: C5H8Cl2N2
Formula Weight: 167.04
MOL File: 78667-04-6.mol

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2-(CHLOROMETHYL)-1-METHYL-1H-IMIDAZOLE HYDROCHLORIDE Property

Melting point:: 175 °C
storage temp.: under inert gas (nitrogen or Argon) at 2-8°C
form: powder
color: Beige

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Safety

HS Code: 2933299090

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

TRC

Product number: C587955
Product name: 2-(Chloromethyl)-1-Methyl-1H-ImidazoleHydrochloride
Packaging: 50mg
Price: $45
Updated: 2021/12/16

SynQuest Laboratories

Product number: 3H32-5-N7
Product name: 2-(Chloromethyl)-1-methyl-1H-imidazolehydrochloride
Packaging: 250mg
Price: $48
Updated: 2021/12/16

Matrix Scientific

Product number: 133696
Product name: 2-(Chloromethyl)-1-methyl-1H-imidazolehydrochloride
Purity: 95%+
Packaging: 100mg
Price: $64
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FC124223
Product name: 2-(Chloromethyl)-1-methyl-1H-imidazole hydrochloride
Packaging: 250mg
Price: $85
Updated: 2021/12/16

Matrix Scientific

Product number: 133696
Product name: 2-(Chloromethyl)-1-methyl-1H-imidazolehydrochloride
Purity: 95%+
Packaging: 500mg
Price: $136
Updated: 2021/12/16

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2-(CHLOROMETHYL)-1-METHYL-1H-IMIDAZOLE HYDROCHLORIDE Chemical Properties,Usage,Production

Synthesis

17334-08-6

78667-04-6

General procedure for the synthesis of 2-(chloromethyl)-1-methyl-1H-imidazole hydrochloride (BB7) from 1-methyl-2-hydroxymethyl-1H-imidazole (BB6): to a solution of BB6 (35.5 g, 316.96 mmol) in dichloromethane (DCM, 1500 mL) was slowly added thionyl chloride (SOCl2, 330 mL, 4436 mmol ). The reaction mixture was gradually warmed to room temperature and stirred continuously for 5 hours. Upon completion of the reaction, the mixture was concentrated to remove the solvent. The residue was washed sequentially with dichloromethane (DCM, 2 × 500 mL) and ether (Et2O, 2 × 200 mL) to give the final target product BB7 (50 g, 95% yield) as an off-white solid. Thin-layer chromatography (TLC) showed an Rf value of 0.4 (unfolding agent: ethyl acetate).1H NMR (400 MHz, DMSO-d6) data were as follows: δ 7.76 (1H, apparent double peaks), 7.70 (1H, apparent double peaks), 5.17 (2H, single peak), 3.87 (3H, single peak); mass spectrometry (MS) showed an m/z of 131 ([M+H]+ ).

References

[1] Patent: US2012/322722, 2012, A1
[2] Tetrahedron Letters, 2011, vol. 52, # 41, p. 5308 - 5310
[3] Tetrahedron, 1996, vol. 52, # 48, p. 15171 - 15188
[4] Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1993, # 19, p. 2291 - 2302
[5] Tetrahedron Letters, 2013, vol. 54, # 45, p. 6087 - 6089

2-(CHLOROMETHYL)-1-METHYL-1H-IMIDAZOLE HYDROCHLORIDE Preparation Products And Raw materials

Raw materials

Preparation Products

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2-(CHLOROMETHYL)-1-METHYL-1H-IMIDAZOLE HYDROCHLORIDE Suppliers

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View Lastest Price from 2-(CHLOROMETHYL)-1-METHYL-1H-IMIDAZOLE HYDROCHLORIDE manufacturers

Career Henan Chemical Co

Product: 2-(CHLOROMETHYL)-1-METHYL-1H-IMIDAZOLE HYDROCHLORIDE 78667-04-6
Price: US $6.60/KG
Min. Order: 1KG
Purity: 97%-99%
Supply Ability: 1kg -1000kg
Release date: 2020-01-02

78667-04-6, 2-(CHLOROMETHYL)-1-METHYL-1H-IMIDAZOLE HYDROCHLORIDERelated Search:

2-(CHLOROMETHYL)-1-METHYL-1H-IMIDAZOLE HYDROCHLORIDE 1-BENZYL-2-(CHLOROMETHYL)-1H-IMIDAZOLE HCL 3-METHYLUNDECANE 2-(CHLOROMETHYL)-1-METHYL-1H-IMIDAZOLE IMIDAZOLE HYDROCHLORIDE 8-CHLORO-2-CHLOROMETHYL-6-TRIFLUOROMETHYL-IMIDAZO[1,2-A]PYRIDINE 1-BENZYL-2-CHLOROMETHYL-1H-BENZOIMIDAZOLE HYDROCHLORIDE 8-CHLORO-2-(CHLOROMETHYL)IMIDAZO[1,2-A]PYRIDINE 6,8-DICHLORO-IMIDAZO[1,2-A]PYRIDINE-2-CARBALDEHYDE ethyl 6,8-dichloroimidazo[1,2-a]pyridine-2-carboxylate 5-CHLORO-2-(CHLOROMETHYL)-1-METHYL-1H-IMIDAZOLE HYDROCHLORIDE 5-(Chloromethyl)-4-methyl-1H-imidazole hydrochloride 2-[6-CHLORO-2-(CHLOROMETHYL)-1H-BENZIMIDAZOL-1-YL]ETHANOL [4-(6,8-DICHLORO-2-METHYL-IMIDAZO[1,2-A]PYRIDIN-3-YL)-THIAZOL-2-YL]-HYDRAZINE 1-(4-CHLOROBENZYL)-2-(CHLOROMETHYL)-1H-IMIDAZOLE HYDROCHLORIDE 2-(1,3-BENZODIOXOL-5-YL)-3,8-DICHLORO-6-(TRIFLUOROMETHYL)IMIDAZO[1,2-A]PYRIDINE 8-CHLORO-2-(3,4-DICHLOROPHENYL)-6-(TRIFLUOROMETHYL)IMIDAZO[1,2-A]PYRIDINE 6,8-dichloro-2-(chloromethyl)imidazo[1,2-a]pyridine

2-(Chloromethyl)-1-methyl-1H-imidazole hydrochloride 95%

2-CHLOROMETHYL-1-METHYL-1H-IMIDAZOLE HCL

2-(CHLOROMETHYL)-1-METHYL-1H-IMIDAZOLE HYDROCHLORIDE

1-Methyl-2-(chloromethyl)imidazole hydrochloride

2-(Chloromethyl)-1-methylimidazole hydrochloride

1H-IMidazole,2-(chloroMethyl)-1-Methyl-, hydrochloride (1:1)

2-Chloromethyl-1-methyl-1H-imida

78667-04-6