IMIDAZOLE HYDROCHLORIDE
- Product Name
- IMIDAZOLE HYDROCHLORIDE
- CAS No.
- 1467-16-9
- Chemical Name
- IMIDAZOLE HYDROCHLORIDE
- Synonyms
- Imidazolium chloride;1H-iMidazole hydrochloride;AMerican CustoM CheMicals Corporation;ImidazoleHCl;Imidazole salt;Imidazole-HCl 98%;midazole hydrochloride;IMIDAZOLE HYDROCHLORIDE;GLYOXALINE, HYDROCHLORIDE;Imidazole hydrochloride 99%
- CBNumber
- CB5212747
- Molecular Formula
- C3H5ClN2
- Formula Weight
- 104.54
- MOL File
- 1467-16-9.mol
IMIDAZOLE HYDROCHLORIDE Property
- Melting point:
- 158-161 °C(lit.)
- storage temp.
- Inert atmosphere,Room Temperature
- solubility
- H2O: 50 mg/mL, clear, colorless
- form
- solid
- color
- Pale yellow
- PH
- 9.0-10.0
- BRN
- 3678283
- Stability:
- Stable. Hygroscopic. Incompatible with strong oxidizing agents.
- InChI
- InChI=1S/C3H4N2.ClH/c1-2-5-3-4-1;/h1-3H,(H,4,5);1H
- InChIKey
- JDIIGWSSTNUWGK-UHFFFAOYSA-N
- SMILES
- C1NC=NC=1.Cl
- CAS DataBase Reference
- 1467-16-9(CAS DataBase Reference)
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
- Precautionary statements
-
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P332+P313IF SKIN irritation occurs: Get medical advice/attention.
P337+P313IF eye irritation persists: Get medical advice/attention.
N-Bromosuccinimide Price
- Product number
- I3386
- Product name
- Imidazole hydrochloride
- Packaging
- 100g
- Price
- $58.2
- Updated
- 2025/07/31
- Product number
- I3386
- Product name
- Imidazole hydrochloride
- Packaging
- 500g
- Price
- $179
- Updated
- 2025/07/31
- Product number
- I387618
- Product name
- Imidazole hydrochloride
- Packaging
- 2.5g
- Price
- $75
- Updated
- 2021/12/16
- Product number
- I387618
- Product name
- Imidazole hydrochloride
- Packaging
- 500mg
- Price
- $60
- Updated
- 2021/12/16
- Product number
- OR924059
- Product name
- Imidazole hydrochloride
- Purity
- 99%
- Packaging
- 100g
- Price
- $48
- Updated
- 2021/12/16
IMIDAZOLE HYDROCHLORIDE Chemical Properties,Usage,Production
Chemical Properties
white powder
Uses
Imidazole hydrochloride is a useful research chemical.
Uses
Imidazole hydrochloride has been used:
- in double immunohistochemistry
- to determine the activity of octopine dehydrogenase (ODH) in Mytilus galloprovincialis
- to study the cytoskeletal features during in vitro fertilization after intracytoplasmic sperm injection (ICSI) among humans
- as a reagent in the synthesis of a probe for monitoring herpes simplex virus type 1 thymidine kinase (HSV1-tk) reporter gene expression in rodents
Synthesis
288-32-4
75-44-5
1467-16-9
530-62-1
In a flask, 68.22 g of imidazole was suspended in 505 g of xylene. The mixture was heated to reflux and 5 g of the xylene/water azeotropic mixture was removed by distillation to achieve dehydration. Subsequently, the temperature of the reaction system was lowered to 66°C and 25.2 grams of phosgene was added dropwise at a rate of 50.4 grams/hour over 30 minutes. After about 15 minutes, the viscosity of the reaction mixture increased significantly, exhibiting a chewing gum-like consistency. During the phosgene dropwise addition, the by-product imidazole hydrochloride precipitated in the form of yellow globules. After maintaining this temperature and continuing stirring for 1 hour, the reaction temperature was raised to 130 °C, at which time the imidazole hydrochloride transformed into a brown molten state. The melt was discharged from the reaction system at 130°C and solidified to a dark green solid upon cooling. The supernatant xylene phase was cooled to 0 °C, the precipitated crystals were filtered and dried at 20 mbar and 50 °C. A white crystalline N,N'-carbonyl diimidazole with a small amount of black impurities (Hazen color number: 489) was finally obtained with a purity of 96.8%, corresponding to 70% of the theoretical yield.
References
[1] Patent: US2005/272937, 2005, A1. Location in patent: Page/Page column 4
[2] Patent: US2005/272937, 2005, A1. Location in patent: Page/Page column 4
[3] Patent: US2005/272937, 2005, A1. Location in patent: Page/Page column 3-4; 5
IMIDAZOLE HYDROCHLORIDE Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from IMIDAZOLE HYDROCHLORIDE manufacturers
- Product
- IMIDAZOLE HYDROCHLORIDE 1467-16-9
- Price
- US $0.00-0.00/KG
- Min. Order
- 1KG
- Purity
- 98%
- Supply Ability
- 1ton
- Release date
- 2022-09-26
- Product
- IMIDAZOLE HYDROCHLORIDE 1467-16-9
- Price
- US $15.00-10.00/KG
- Min. Order
- 1KG
- Purity
- 99%+ HPLC
- Supply Ability
- Monthly supply of 1 ton
- Release date
- 2021-07-11
- Product
- IMIDAZOLE HYDROCHLORIDE 1467-16-9
- Price
- US $15.00-10.00/KG
- Min. Order
- 1KG
- Purity
- 99%+ HPLC
- Supply Ability
- Monthly supply of 1 ton
- Release date
- 2021-07-09