17ALPHA-HYDROXYPREGNENOLONE
- Product Name
- 17ALPHA-HYDROXYPREGNENOLONE
- CAS No.
- 387-79-1
- Chemical Name
- 17ALPHA-HYDROXYPREGNENOLONE
- Synonyms
- NSC 63853;17-OH PREG;17alpha-Hydroxy;17-OH Pregnenolone;Dronedarone HCl-d6;Hydroxypregnenolone;17a-Hydroxypregnolone;17A-HYDROXYPREGENOLONE;17-HYDROXYPREGNENOLONE;17α-Hydroxypregnenolone
- CBNumber
- CB3175435
- Molecular Formula
- C21H32O3
- Formula Weight
- 332.48
- MOL File
- 387-79-1.mol
17ALPHA-HYDROXYPREGNENOLONE Property
- Melting point:
- 273℃
- Flash point:
- 9℃
- storage temp.
- -20°C
- solubility
- Chloroform (Slightly), DMSO (Slightly, Heated, Sonicated)
- form
- Solid
- Boiling point:
- 478.4±45.0 °C(Predicted)
- Density
- 1.15±0.1 g/cm3(Predicted)
- pka
- 13.02±0.70(Predicted)
- color
- White to Off-White
- CAS DataBase Reference
- 387-79-1(CAS DataBase Reference)
Safety
- Hazard Codes
- F,T
- Risk Statements
- 11-23/24/25-39/23/24/25
- Safety Statements
- 7-16-36/37-45
- RIDADR
- UN1230 - class 3 - PG 2 - Methanol
- WGK Germany
- 3
- RTECS
- TU5548000
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Danger
- Hazard statements
-
H225Highly Flammable liquid and vapour
H370Causes damage to organs
- Precautionary statements
-
P210Keep away from heat/sparks/open flames/hot surfaces. — No smoking.
P260Do not breathe dust/fume/gas/mist/vapours/spray.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P301+P310IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.
P311Call a POISON CENTER or doctor/physician.
N-Bromosuccinimide Price
- Product number
- H5002
- Product name
- 17α-Hydroxypregnenolone
- Packaging
- 5g
- Price
- $562
- Updated
- 2024/03/01
- Product number
- H-105
- Product name
- 17α-Hydroxypregnenolone solution
- Purity
- 100?μg/mL in methanol, ampule of 1?mL, certified reference material, Cerilliant?
- Packaging
- 1mL
- Price
- $128
- Updated
- 2024/03/01
- Product number
- S518034
- Product name
- 3BETA,17ALPHA-DIHYDROXYPREGN-5-EN-20-ONE
- Purity
- AldrichCPR
- Packaging
- 250MG
- Price
- $28.6
- Updated
- 2022/05/15
- Product number
- R199400
- Product name
- 3-BETA,17-ALPHA-DIHYDROXYPREGN-5-EN-20-ONE
- Purity
- AldrichCPR
- Packaging
- 1MG
- Price
- $28.6
- Updated
- 2022/05/15
- Product number
- 29181
- Product name
- 17α-hydroxy Pregnenolone
- Packaging
- 100mg
- Price
- $44
- Updated
- 2024/03/01
17ALPHA-HYDROXYPREGNENOLONE Chemical Properties,Usage,Production
Description
17α-hydroxy Pregnenolone is a metabolite of pregnenolone and a precursor in the biosynthesis of dehydroepiandrosterone (DHEA; ). It is formed from pregnenolone by cytochrome P450 (CYP) isoform CYP17A1 hydroxylase activity and then converted to dehydroepiandrosterone by CYP17A1-mediated 17,20-lyase activity. Plasma levels of 17α-hydroxy pregnenolone are elevated in patients with type II 3β-hydroxysteroid dehydrogenase deficiency, a form of congenital adrenal hyperplasia.
Uses
17α-hydroxypregnenolone has been used as a substrate for the enzyme 3β‐hydroxysteroid dehydrogenase (3β‐HSD) expressed in COS1 cells.
General Description
17α-hydroxypregnenolone is a derived from pregnenolone.
Biochem/physiol Actions
17α-hydroxypregnenolone acts as a precursor for cortisol and sex steroids.
17ALPHA-HYDROXYPREGNENOLONE Preparation Products And Raw materials
Raw materials
Preparation Products
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