Nitrapyrin Property

Melting point:

62-63°C

Boiling point:

136-138°C

Density 

1.8732 (rough estimate)

vapor pressure 

2.8 x 10^-3 mmHg at 20 °C (quoted, Verschueren, 1983)

refractive index 

1.6000 (estimate)

Flash point:

100 °C

storage temp. 

Keep in dark place,Sealed in dry,Room Temperature

solubility 

Soluble in 10 mg/ml ethanol.

form 

Powder

pka

-3.75±0.10(Predicted)

Specific Gravity

1.579 (25℃)

color 

White

Water Solubility 

Insoluble. <0.01 g/100 mL at 18 ºC

Merck 

14,6574

BRN 

1618997

Henry's Law Constant

2.13 x 10^-3 atm?m³/mol (approximate - calculated from water solubility and vapor pressure)

Exposure limits

NIOSH REL: 10 mg/m3, STEL 20 mg/m3 (total), 5 mg/m3 (respirable fraction); OSHA PEL: 15 mg/m3 (total), 5 mg/m3 (respirable fraction); ACGIH TLV: TWA 10 mg/m3.

InChIKey

DCUJJWWUNKIJPH-UHFFFAOYSA-N

LogP

3.325-3.41 at 23.5℃

CAS DataBase Reference

1929-82-4(CAS DataBase Reference)

NIST Chemistry Reference

Pyridine, 2-chloro-6-(trichloromethyl)-(1929-82-4)

EPA Substance Registry System

Nitrapyrin (1929-82-4)

Safety

Hazard Codes 

Xn;N,Xi,N,Xn

Risk Statements 

22-51/53-36/37/38

Safety Statements 

24-61-37/39-26

RIDADR 

UN 2811

OEB

B

OEL

TWA: 10 mg/m3 (total), STEL: 20 mg/m3 (total)

WGK Germany 

2

RTECS 

US7525000

TSCA 

Yes

HazardClass 

6.1(b)

PackingGroup 

III

HS Code 

29333990

Toxicity

LC50 for channel catfish 5.8 mg/L (Worthing and Hance, 1991); acute oral LD50 for rats 1,230 mg/kg (Verschueren, 1983), 940 mg/kg (RTECS, 1985).

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H302Harmful if swallowed

H311Toxic in contact with skin

H411Toxic to aquatic life with long lasting effects

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P273Avoid release to the environment.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

Nitrapyrin Chemical Properties,Usage,Production

Uses

2-​Chloro-​6-​(trichloromethyl)​pyridine is a nitrification inhibitor used to limit NO and N2O emissions from crops. Improves nitrogen use efficiency. Environmental toxin on US EPA Toxic Release Inventory list (TRI) list.

Chemical Properties

Crystals.

Physical properties

Colorless to white crystalline solid with a mild, sweet odor

Uses

2-Chloro-6-(trichloromethyl)pyridine is

Uses

Fertilizer additive to control nitrification and prevent loss of soil nitrogen.

Uses

Bactericide used to inhibit Nitrosomonas spp. from oxidizing ammonium ions in soil.

Definition

ChEBI: Nitrapyrin is a chloropyridine that is 2-chloropyridine which is substituted by a trichloromethyl group at position 6. It is a nitrification inhibitor that is co-applied with nitrogen fertilizer in agroecosystems. It has a role as a nitrification inhibitor, an antibacterial agent and an agrochemical.

General Description

Colorless crystals or off-white crystalline solid.

Air & Water Reactions

Insoluble in water.

Reactivity Profile

Nitrapyrin is a base. Reacts exothermically with acids.

Hazard

Liver damage. Questionable carcinogen.

Fire Hazard

Flash point data for Nitrapyrin are not available. Nitrapyrin is probably combustible.

Flammability and Explosibility

Non flammable

Agricultural Uses

Nitrapyrin, also called N serve, is a nitrification inhibitor

Safety Profile

Poison by ingestion. Moderately toxic by skin contact. Experimental reproductive effects. Mutation data reported. When heated to decomposition it emits very toxic fumes of Cland NOx.

Environmental Fate

Biological. 6-Chloropicolinic acid and carbon dioxide were reported as biodegradation products (Verschueren, 1983).
Soil. Hydrolyzes in soil to 6-chloropyridine-2-carboxylic acid (Worthing and Hance, 1991).
Photolytic. Photolysis of nitrapyrin in water yielded 6-chloropicolinic acid, 6-hydroxypicolinic acid and an unidentified polar material (Verschueren, 1983).
Chemical/Physical. Emits toxic fumes of nitrogen oxides and chlorides when heated to decomposition (Sax and Lewis, 1987; Lewis, 1990).