ChemicalBook > CAS DataBase List > N-(2-Acetamido)iminodiacetic acid

N-(2-Acetamido)iminodiacetic acid

Product Name
N-(2-Acetamido)iminodiacetic acid
CAS No.
26239-55-4
Chemical Name
N-(2-Acetamido)iminodiacetic acid
Synonyms
ADA;ADA,97%;ADA,98+%;ADA buffe;ADA BUFFER;Adogen 342D;ADA FREE ACID;ADA buffe ADA;ADA SIGMAULTRA;Einecs 247-530-0
CBNumber
CB3183520
Molecular Formula
C6H10N2O5
Formula Weight
190.15
MOL File
26239-55-4.mol
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N-(2-Acetamido)iminodiacetic acid Property

Melting point:
219 °C (dec.)(lit.)
Boiling point:
325.64°C (rough estimate)
Density 
1.4957 (rough estimate)
vapor pressure 
0Pa at 25℃
refractive index 
1.5010 (estimate)
storage temp. 
room temp
solubility 
1 M NaOH: 0.05 M at 20 °C, clear, colorless
form 
Powder
color 
White to almost white
PH
1.5-3.0 (25℃, 0.01M in H2O)
pka
6.6(at 25℃)
PH Range
6.0 - 7.2
Water Solubility 
soluble
λmax
λ: 260 nm Amax: 0.20
λ: 280 nm Amax: 0.05
Merck 
14,147
BRN 
1787181
InChIKey
QZTKDVCDBIDYMD-UHFFFAOYSA-N
LogP
-3.12 at 20℃
CAS DataBase Reference
26239-55-4(CAS DataBase Reference)
EPA Substance Registry System
Glycine, N-(2-amino-2-oxoethyl)-N-(carboxymethyl)- (26239-55-4)
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Safety

Safety Statements 
24/25
WGK Germany 
3
TSCA 
Yes
HazardClass 
IRRITANT
HS Code 
29241900
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
00307
Product name
ADA
Purity
BioUltra, ≥99.0% (T)
Packaging
5g
Price
$40.7
Updated
2023/06/20
Sigma-Aldrich
Product number
8.41227
Product name
N-(2-Acetamido)-iminodiacetic acid
Purity
for synthesis
Packaging
25g
Price
$76.6
Updated
2023/06/20
Sigma-Aldrich
Product number
00307
Product name
ADA
Purity
BioUltra, ≥99.0% (T)
Packaging
25g
Price
$107
Updated
2023/06/20
TCI Chemical
Product number
A0699
Product name
N-(2-Acetamido)iminodiacetic Acid
Purity
>98.0%(T)
Packaging
25g
Price
$43
Updated
2024/03/01
TCI Chemical
Product number
A0699
Product name
N-(2-Acetamido)iminodiacetic Acid
Purity
>98.0%(T)
Packaging
500g
Price
$398
Updated
2024/03/01
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N-(2-Acetamido)iminodiacetic acid Chemical Properties,Usage,Production

Description

N-(2-Acetamido)iminodiacetic acid is a zwitterionic buffer used in biochemistry and molecular biology. It is one of the Good buffers developed in the 1960′s to provide buffers in the pH range of 6.15 - 8.35 for wide applicability to biochemical studies. The pioneering publication by Good and co-workers describes the synthesis of ADA and its physical properties. The useful range of ADA buffer in aqueous solution is 6.0 - 7.2.

Chemical Properties

N-(2-Acetamido)iminodiacetic acid is white to almost white powder

Uses

N-(2-Acetamido)iminodiacetic acid (ADA) could prevents oxidation and irreversible denaturation of proteins while conducting gel electrophoresis. Furthermore studies suggest that ADA interferes with BCA and Lowry protein assays. Also ADA often chelates metal ions such as Mn(II), Cu(II), Ni(II), Zn(II), and Co(II) in a 2:1 at or below physiological pH values. Moreover, ADA is soluble in sodium hydroxide and absorbs UV radiation in the range below 260nm.

Uses

N-(2-Acetamido)iminodiacetic acid is buffer for biological systems and chelator for metals.

Uses

Biological buffer component with sodium hydroxide and sodium chloride (pH 5.67-7.57, useful pH range 6.4-7.4).Used to prepare immobilized pH gradients.

Application

ADA, or N-(2-Acetamido)iminodiacetic acid, can be used to study biological buffers and zwitterionic compounds. ADA has been used in a study to describe the application of scanning capacitively coupled contactless conductivity detection (SC(4)D) for the determination of pH dependant behaviour of two aminopolycarboxylates immobilised onto the surface of a monolithic capillary column.
Biological buffer component with sodium hydroxide and sodium chloride (pH 5.67-7.57, useful pH range 6.4-7.4). Used to prepare immobilized pH gradients.

Definition

ChEBI: 2,2'-[(2-amino-2-oxoethyl)imino]diacetic acid is a tricarboxylic acid amide that is a Good's buffer substance, pKa = 6.6 at 20 ℃. It is a dicarboxylic acid, a tricarboxylic acid amide and an ADA. It is functionally related to a nitrilotriacetic acid. It is a conjugate acid of a 2,2'-[(2-amino-2-oxoethyl)imino]diacetate(1-).

Flammability and Explosibility

Not classified

Purification Methods

Dissolve ADA in water, add one equivalent of NaOH solution (to final pH of 8-9), then acidify with HCl to precipitate the free acid. This is filtered off, washed with water and dried in vacuo. [Beilstein 4 IV 2441.]

N-(2-Acetamido)iminodiacetic acid Preparation Products And Raw materials

Raw materials

Preparation Products

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N-(2-Acetamido)iminodiacetic acid Suppliers

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View Lastest Price from N-(2-Acetamido)iminodiacetic acid manufacturers

WUHAN FORTUNA CHEMICAL CO., LTD
Product
N-(2-Acetamido)iminodiacetic acid 26239-55-4
Price
US $0.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
3500kg/month
Release date
2021-09-09
Watson Biotechnology Co.,Ltd
Product
N-(2-Acetamido)iminodiacetic acid 26239-55-4
Price
US $0.00-0.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
20MT
Release date
2024-08-22
Hebei Chuanghai Biotechnology Co,.LTD
Product
N- (2-Acetamido) Iminodiacetic Acid 26239-55-4
Price
US $5.00-2.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
10000kg
Release date
2024-08-15

26239-55-4, N-(2-Acetamido)iminodiacetic acidRelated Search:

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