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N-NITROSOMORPHOLINE

Product Name
N-NITROSOMORPHOLINE
CAS No.
59-89-2
Chemical Name
N-NITROSOMORPHOLINE
Synonyms
NMOR;NSC 139;nci-c02164;M2-Impurity D;N-Nitrosomorfolin;NITROSOMORPHOLINE;N-Nitrosomorpholin;4-Nitrosomorpholine;4-nitroso-morpholin;n-nitroso-morpholin
CBNumber
CB3185221
Molecular Formula
C4H8N2O2
Formula Weight
116.12
MOL File
59-89-2.mol
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N-NITROSOMORPHOLINE Property

Melting point:
29°C
Boiling point:
225℃
Density 
1.2829 (rough estimate)
refractive index 
1.4880 (estimate)
Flash point:
29 °C
storage temp. 
2-8°C
Water Solubility 
Completely soluble in water
solubility 
DMSO : 100 mg/mL (861.18 mM)
form 
<29°C Solid,>29°C Liquid
pka
-5.72±0.20(Predicted)
color 
White or Colorless to Yellow
Merck 
14,6640
Stability:
Stable, but light-sensitive. Combustible. Incompatible with strong oxidizing agents. Refrigerate, store in the dark.
IARC
2B (Vol. 17, Sup 7) 1987
EPA Substance Registry System
N-Nitrosomorpholine (59-89-2)
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Safety

Hazard Codes 
Xn,T,F
Risk Statements 
22-40-39/23/24/25-23/24/25-11
Safety Statements 
36/37-45-16-7
RIDADR 
UN 2810 6.1/PG 3
WGK Germany 
3
RTECS 
QE7525000
HS Code 
2934.99.9001
HazardClass 
6.1(b)
PackingGroup 
III
Hazardous Substances Data
59-89-2(Hazardous Substances Data)
Toxicity
LD50 orally in rats: 282 mg/kg (Druckrey)
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H301Toxic if swalloed

H351Suspected of causing cancer

Precautionary statements

P201Obtain special instructions before use.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
N7382
Product name
Nitrosomorpholine
Packaging
1ml
Price
$158
Updated
2024/03/01
Sigma-Aldrich
Product number
N7382
Product name
Nitrosomorpholine
Packaging
5ml
Price
$322.2
Updated
2024/03/01
TCI Chemical
Product number
N0466
Product name
N-Nitrosomorpholine
Purity
>99.0%(GC)
Packaging
5g
Price
$253
Updated
2024/03/01
TCI Chemical
Product number
N0466
Product name
N-Nitrosomorpholine
Purity
>99.0%(GC)
Packaging
25g
Price
$748
Updated
2024/03/01
Sigma-Aldrich
Product number
Y0000822
Product name
Molsidomine impurity B
Purity
European Pharmacopoeia (EP) Reference Standard
Packaging
y0000822
Price
$150
Updated
2024/03/01
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N-NITROSOMORPHOLINE Chemical Properties,Usage,Production

Chemical Properties

yellow crystals or gold liquid

Uses

Solvent for polyacrylonitrile; present during rubber manufacturing

Uses

N-Nitrosomorpholine, a frequently used genotoxic model carcinogen. Toxicogenomic analysis of N-Nitrosomorpholine induced changes in rat liver.

Definition

ChEBI: A nitrosamine that is morpholine in which the hydrogen attached to the nitrogen is replaced by a nitroso group. A carcinogen and mutagen, it is found in snuff tobacco.

Synthesis Reference(s)

Synthetic Communications, 22, p. 2607, 1992 DOI: 10.1080/00397919208021659

General Description

Yellow crystals. Golden liquid with many crystals at 68°F.

Air & Water Reactions

Water soluble.

Reactivity Profile

N-NITROSOMORPHOLINE is incompatible with strong oxidizing agents .

Health Hazard

ACUTE/CHRONIC HAZARDS: When heated to decomposition N-NITROSOMORPHOLINE emits toxic fumes of nitrogen oxides.

Fire Hazard

Flash point data for N-NITROSOMORPHOLINE are not available; however, N-NITROSOMORPHOLINE is probably combustible.

Biochem/physiol Actions

Tumor initiator in rodent liver, trachea, nasal cavity, esophagus, kidney, lung, and thyroid.

Safety Profile

Confirmed carcinogen with experimental carcinogenic, neoplastigenic, and tumorigenic data. Poison by ingestion, intraperitoneal, subcutaneous, and intravenous routes. Moderately toxic by inhalation. Human mutation data reported. Experimental reproductive effects. When heated to decomposition it emits toxic fumes of NOx. See also N-NITROSO COMPOUNDS.

Carcinogenicity

N-Nitrosomorpholine is reasonably anticipated to be a human carcinogen based on sufficient evidence of carcinogenicity from studies in experimental animals.

N-NITROSOMORPHOLINE Preparation Products And Raw materials

Raw materials

Preparation Products

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N-NITROSOMORPHOLINE Suppliers

TargetMol Chemicals Inc.
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United States
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View Lastest Price from N-NITROSOMORPHOLINE manufacturers

ShenZhen H&D Pharmaceutical Technology Co., LTD
Product
N-nitrosomorpholine 59-89-2
Price
US $0.00-0.00/mg
Min. Order
10mg
Purity
0.98
Supply Ability
10g
Release date
2024-04-26

59-89-2, N-NITROSOMORPHOLINERelated Search:


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