ChemicalBook > CAS DataBase List > H-ARG-SER-ARG-THR-ARG-GLN-PHE-TYR-GLY-LEU-MET-NH2

H-ARG-SER-ARG-THR-ARG-GLN-PHE-TYR-GLY-LEU-MET-NH2

Product Name
H-ARG-SER-ARG-THR-ARG-GLN-PHE-TYR-GLY-LEU-MET-NH2
CAS No.
208041-90-1
Chemical Name
H-ARG-SER-ARG-THR-ARG-GLN-PHE-TYR-GLY-LEU-MET-NH2
Synonyms
HEMOKININ-1;HK-1, MOUSE;HEK-1, MOUSE;HK-1 (MOUSE, RAT);HEK-1 (MOUSE, RAT);HEMOKININ 1 (MOUSE);H2N-RSRTRQFYGLM-AMIDE;HEMOKININ 1 (MOUSE, RAT);HEMOKININ 1 MOUSE?, >98%;Hemokinin 1 mouse,RSRTRQFYGLM, >98%
CBNumber
CB3195426
Molecular Formula
C61H100N22O15S
Formula Weight
1413.65
MOL File
208041-90-1.mol
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H-ARG-SER-ARG-THR-ARG-GLN-PHE-TYR-GLY-LEU-MET-NH2 Property

Density 
1.48±0.1 g/cm3(Predicted)
storage temp. 
−20°C
solubility 
H2O: soluble
pka
9.82±0.15(Predicted)
form 
powder
color 
white
Water Solubility 
Soluble to 2 mg/ml in water
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Safety

Safety Statements 
22-24/25
WGK Germany 
3
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

ChemScene
Product number
CS-7597
Product name
Hemokinin1mouse
Purity
98.41%
Packaging
1mg
Price
$180
Updated
2021/12/16
Biorbyt Ltd
Product number
orb372368
Product name
Hemokinin 1
Purity
> 95%
Packaging
1mg
Price
$353.6
Updated
2021/12/16
Biorbyt Ltd
Product number
orb372369
Product name
Hemokinin 1
Purity
> 95%
Packaging
1mg
Price
$353.6
Updated
2021/12/16
ChemScene
Product number
CS-7597
Product name
Hemokinin1mouse
Purity
98.41%
Packaging
5mg
Price
$540
Updated
2021/12/16
Biorbyt Ltd
Product number
orb372369
Product name
Hemokinin 1
Purity
> 95%
Packaging
5mg
Price
$688.5
Updated
2021/12/16
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H-ARG-SER-ARG-THR-ARG-GLN-PHE-TYR-GLY-LEU-MET-NH2 Chemical Properties,Usage,Production

Uses

Hemokinin 1 (mouse) is a selective agonist of neurokinin-1 receptor, with Ki of 0.175 nM and 560 nM for human NK1 receptor and human NK2 receptor, respectively.

in vivo

Hemokinin 1 (mouse) (0.01-100 nmol/kg i.v., n=10) induces a dose-related hypotension that is maximal at the dose of 10 nmol/kg. For systolic blood pressure (SBP), the ED50 value is 0.2 nmol/kg (0.1-0.4 nmol/kg) for Hemokinin 1 (mouse). For diastolic blood pressure (DBP), the ED50 value is 0.1 nmol/kg (0.07-0.2 nmol/kg) for Hemokinin 1 (mouse). Hemokinin 1 (mouse) (0.1-100 nmol/kg, i.v.) induces a dose-related salivary secretion in atropine-pretreated rats[1].

IC 50

NK1

References

[1] Francesca Bellucci, et al. Pharmacological profile of the novel mammalian tachykinin, hemokinin 1. Br J Pharmacol. 2002 Jan; 135(1): 266-274

H-ARG-SER-ARG-THR-ARG-GLN-PHE-TYR-GLY-LEU-MET-NH2 Preparation Products And Raw materials

Raw materials

Preparation Products

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H-ARG-SER-ARG-THR-ARG-GLN-PHE-TYR-GLY-LEU-MET-NH2 Suppliers

China 77 Europe 1 France 1 Germany 2 Switzerland 1 United Kingdom 1 United States 8 USA 1 Global 92
3B Pharmachem (Wuhan) International Co.,Ltd.
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821-50328103-801 18930552037
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China
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86-21-61263399
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010-50973130 18101056239
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3193328036@qq.com
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Nanjing Leon Biological Technology Co., Ltd.
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17705183659
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View Lastest Price from H-ARG-SER-ARG-THR-ARG-GLN-PHE-TYR-GLY-LEU-MET-NH2 manufacturers

Career Henan Chemical Co
Product
H-ARG-SER-ARG-THR-ARG-GLN-PHE-TYR-GLY-LEU-MET-NH2 208041-90-1
Price
US $1.00/g
Min. Order
1g
Purity
≥98%
Supply Ability
g/kg/Ton
Release date
2020-03-05

208041-90-1, H-ARG-SER-ARG-THR-ARG-GLN-PHE-TYR-GLY-LEU-MET-NH2Related Search:

GLY-LEU-MET-NH2 ARG-SER-ARG-THR-ARG-GLN-PHE-TYR-GLY-LEU-MET-NH2 TFA SALT H-ARG-SER-ARG-THR-ARG-GLN-PHE-TYR-GLY-LEU-MET-NH2

  • HK-1, MOUSE
  • HK-1 (MOUSE, RAT)
  • H-ARG-SER-ARG-THR-ARG-GLN-PHE-TYR-GLY-LEU-MET-NH2
  • H2N-RSRTRQFYGLM-AMIDE
  • HEMOKININ 1 (MOUSE)
  • HEMOKININ 1 (MOUSE, RAT)
  • HEK-1, MOUSE
  • HEK-1 (MOUSE, RAT)
  • ARG-SER-ARG-THR-ARG-GLN-PHE-TYR-GLY-LEU-MET-NH2
  • TACHYKININ 4 PRECURSOR (56-66) AMIDE [RATTUS NORVEGICUS]/[MUS MUSCULUS]
  • HEMOKININ-1
  • HeMokinin 1 (Mouse, rat) HK-1 (Mouse, rat), HEK-1 (Mouse, rat)
  • HK-1 (Mouse, rat), HEK-1 (Mouse, rat)
  • Hemokinin 1 mouse,RSRTRQFYGLM, >98%
  • HEMOKININ 1 MOUSE?, >98%
  • L-Methioninamide, L-arginyl-L-seryl-L-arginyl-L-threonyl-L-arginyl-L-glutaminyl-L-phenylalanyl-L-tyrosylglycyl-L-leucyl-
  • 208041-90-1
  • 20804-90-1
  • C61H100N22O15S
  • Tachykinin receptor